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Help! drugs,radiation for mets Spine Please
Met with oncology and response back from Neurosurgeon, they are going to have a conversation about mt T-8-9 lesion that has grown, and has fluid around it again. Getting IT Herceptin 100mg per week via Omaya. Need possibly another her 2 antagonist that crosses Blood Brain Barrier. Also take Tykerb 750 daily. Failed Navelbine due to its side effects and left shift in the blood work. I know people were talking about Topotecan, but I can not find any trials or info that validated the use of it Intrathecal. Neuro wise I am so so but getting a little more symptomatic again. I had rads to the T-3-4 and T-8-9 for total of 4050cGY so do not think anymore. The last MRI showed of the T3 lesion it was not measurable. It took me over a year to start IT herceptin, and without lots of data out there trying to get anything else approved either IT or off label, is probably a no go.
Treatment options are right now continue on current therapy, and finding another drug, Neuro offered to do surgery, previously but the risk of paralysis is very high, as well as the herceptin not getting rid of it.
Thanks to all, Merry Christmas
Prayers for our families of Our Angels, and healings and Peace for the rest of us as some of us morn the loss of our love ones and face this unasked for journey in our lives.
Darita
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dx 1/06 IDC 2cm 38 at dx
2/06 L mast nodes 3/9+ SNB neg ER-/Pr - her2 + Stg 4 liver/pelvis
3/06-9/06Taxol/Carbo/zometa/Herceptin
3/07 6 brain mets WBR down to c-2
4/07 osteonecrosis jaw
1/08 mri new 9mm lesion right lower side
2/08 gamma knife 1 lesion 11/08 regamma
10/09 latent rad necrosis to brain met,
1/20/10 crani: lesion necrosis w active cells continue her add tykerb
1/11 NED just Ingrown toenail! YEAH GOD
8/11 Tykerb, herceptin weekly, elevated her2 levels, negative scans
oct -march 11 new neuro deficits lower legs
3/12 2 spinal metsTykerb, Herceptin
04/12 4050cGY rads T 2-4 & T7-9
5/12 Brain,cervical lumbar clear/thoracic slight decrease
10/12 t 2-4 shrunk t-9 grew start Xeloda, 02/13 stop xeloda,5/13 on metformin, decadron, Tykerb, iv and IT herceptin 5/30/13 total #11 #2 of 80mg dose weekly.
9/13 100mg of IT her, IV hern, 750 mg tykerb, 3mg dec.
last Mri T--3 SHRUNK t7-9 shrunk no edema. Left shift in CBC bone marrow BX negative.
10/13 Ct has shown Double left ureters with stones/cysts in them, after 3 births and lots and U/S iit takes cancer to figure out you have 2 smaller ureters going into 1 kidney!
12/13 Mri brain no new lesions, cervical and lumbar arthritis.
Tspine lesion at T3 stable, T 7-9 GROWTH lots of pain
1/29/14 HIHO HIHO its off to Neuro surgery I go
Life is Good when you wake up in the morning and take a breath and know that God has given me another day.
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