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Old 06-22-2008, 06:15 PM   #1
Patty F
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Location: Portage, IN
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Question "Fatty Tumor" Confused by path report

May 29th I had another surgery. I had found a lump and they decided to remove it. Surgeon said right after surgery that it was a fatty tumor and that is was nothing to worry about. I felt good about that. : )
I received my path report that said......Fibroadipose tissue with rare focus of angiolymphatic tumor permeation, (please see comment).
Comment: The slides demonstrate fibroadipose tissue with a rare focus of angiolymphatic tumor embolization. The patients history of breast carcinoma with nodal metestasis and lymphovascular invasion is noted. The findings are compatible with involvement by this process.

Does this mean that they are still finding cancer in the vascular or lymphs?

I have been through 4 A/C and 12 Taxol/Herceptin treatments. Why would I still have cancer in these areas after all this treatment? Does this make for a poorer prognosis for me?

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10/15/07: Diagnosed at age 46 lymph node removal (2)
ER/PR - Her2 +++
11/07: Port Installed
11/07 - 1/08: AC
1/30/08: Right Mast Stage lllC
2/28/08: Start Taxol and Herceptin weekly.
5/15/08: Finished Taxol
8/12/08: Finished 33 Rads
1/29/09: Finished Herceptin
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Old 06-23-2008, 03:39 PM   #2
chrisy
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I do not know the answers to your questions, but if this was my path report my first step would be to ASK my doctor what this means, every word of it. A lot of times these path reports just sound so scary and in the end actually mean nothing - that is, nothing BAD. Too bad they just can't say it in plain English.

Ask your doctor.
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Chris in Scotts Valley
June 2002 extensive hi grade DCIS (pre-cancer-stage 0, clean sentinal node) Mastectomy/implant - no chemo, rads. "cured?"
9/2004 Diag: Stage IV extensive liver mets (!) ER/PR- Her2+++
10/04-3/05 Weekly Taxol/Carboplatin/Herceptin , complete response!
04/05 - 4/07 Herception every 3 wks, Continue NED
04/07 - recurrence to liver - 2 spots, starting tykerb/avastin trial
06/07 8/07 10/07 Scans show stable, continue on Tykerb/Avastin
01/08 Progression in liver
02/08 Begin (TDM1) trial
08/08 NED! It's Working! Continue on TDM1
02/09 Continue NED
02/10 Continue NED. 5/10 9/10 Scans NED 10/10 Scans NED
12/10 Scans not clear....4/11 Scans suggest progression 6/11 progression confirmed in liver
07/11 - 11/11 Herceptin/Xeloda -not working:(
12/11 Begin MM302 Phase I trial - bust:(
03/12 3rd times the charm? AKT trial

5/12 Scan shows reduction! 7/12 More reduction!!!!
8/12 Whoops...progression...trying for Perjeta/Herceptin (plus some more nasty chemo!)
9/12 Start Perjeta/Herceptin, chemo on hold due to infection/wound in leg, added on cycle 2 &3
11/12 Poops! progression in liver, Stop Perjeta/Taxo/Herc
11/12 Navelbine/Herce[ptin - try for a 3 cycles, no go.
2/13 Gemzar/Carbo/Herceptin - no go.
3/13 TACE procedure
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Old 06-23-2008, 07:58 PM   #3
jones7676
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Location: I live in Christmas, MI - located on the shores of Lake Superior.
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I second Chrisy's comments. I'd have them go through the report line by line and pencil in comments or take notes. It could be just that the chemo affected the appearance of the cells or something. Biology is very complicated.....good luck on your deciphering mission.
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Barb

10/03 Radical Mastectomy 3 cm tumor - 1/17 Nodes Stage II B, Her 2 +++ ER-/PR- 11/03 4 AC 4 Taxol 12/05 Stage IV - Lung met , Bone mets - Carbo, Taxotere, Herceptin 9/06 - 2 cm brain tumor 10/06 - Tumor removal surgery - Herceptin Halted 12/06 gamma knife tumor base.1/07 Navelbine/Herceptin 4/07 Rads to R femur 5/07 Stereotactic - new 2 cm brain tumor 4/07 Start Xeloda 5/07 Tykerb added 7/07 Brain MRI clean 10/07 .055 cm brain met found. 12/07 Stereotactic -1 cm brain tumor Start Tykerb 11/07 Abraxane/Herceptin 5/08 Cisplatin, Gemcitabine/Herceptin 6/08 Stereotactic to 1cm 9/08 Stereotactic repeat (growth). 11/08 Pet Scan Good but new tiny met on L lung/dead Brain surgery (no cancer cells found/scar tissue) 1/09 Chemo restarted 2/09 Pet Scan Bad - R larger very active/active L active lymph nodes both sides of chest MRI- mets slight increase 2/09 Start Doxil/Tykerb Treatment
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Old 06-23-2008, 08:25 PM   #4
Becky
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This sounds like what had been lymphovascular invasion and it happened to occur within an area that became a fatty tumor.

If you had positive nodes then you had to have had lymphatic/vascular invasion (as the cancer had to get from the tumor to the node somehow). The only thing you have to ask your onc is - Is it a dead remnant? I would think it is after chemo (and rads I would suppose as fatty tumors are a common result of rads).

Is this the only area - did the fatty tumor form around the area and actually do you a great favor by confining this area?

I personally don't think you have anything to worry about here and that it is a fluke of a find and many of us lumpectomy gals have these dead things in us.

Keep us posted. I am curious as to what your onc will say. Call him tomorrow so you don't have to think about this any longer than that. Smile as much as you can because it does make you feel better.
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Kind regards

Becky

Found lump via BSE
Diagnosed 8/04 at age 45
1.9cm tumor, ER+PR-, Her2 3+(rt side)
2 micromets to sentinel node
Stage 2A
left 3mm DCIS - low grade ER+PR+Her2 neg
lumpectomies 9/7/04
4DD AC followed by 4 DD taxol
Used Leukine instead of Neulasta
35 rads on right side only
4/05 started Tamoxifen
Started Herceptin 4 months after last Taxol due to
trial results and 2005 ASCO meeting & recommendations
Oophorectomy 8/05
Started Arimidex 9/05
Finished Herceptin (16 months) 9/06
Arimidex Only
Prolia every 6 months for osteopenia

NED 18 years!

Said Christopher Robin to Pooh: "You must remember this: You're braver than you believe and stronger than you seem and smarter than you think"
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