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Old 08-05-2009, 05:09 PM   #1
ammebarb
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My Sis has her fourth AC Friday.

I'll be going to her home tomorrow, so we can get an early start on Friday. Hopefully, this is the last AC before she starts weekly Taxol and Herceptin. If anyone has any insights about the next regimen, please be in touch. It was helpful for us to know what to anticipate for the AC treatments. Her doc says that most tolerate the Taxol and Herceptin better than the AC, and we are surely hoping so....she had a tough time with the AC.

We've yet to figure out how I'll participate in the weekly schedule....I can't go back every week, so she may have some church friends accompany her, or her husband could take off a few hours early on Fridays. It will be hard for me not to be with her for treatments, but it's really the few days following treatments that I'm most concerned about. Did those of you who did 12 weekly taxols and herceptin need to have someone with you for the few days following treatment?

Thanks again, so very much, for being here. I'm always keeping you in my prayers.

Barb A.
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Old 08-10-2009, 12:51 PM   #2
Colleens_Husband
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Re: My Sis has her fourth AC Friday.

Barb:

Colleen had four TAC treatments, had her surgery, then had two THC treatments. Colleen said that the THC was three or four times easier than the TAC. Hopefully, your sister will find the same thing.

The adriomycin (THE 'A' in AC) is pretty old school and extremely harsh on the body, but it really shrinks tumors and is a serious cancer killer.

Best luck and wishes to your sister. She is through the hard part now, and God willing, she will have an easier time in the future.

Lee
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This happened to Colleen:

Diagnosed in September 2007
ER-/PR-/HER2 Neu+++ 2.1 cm x .9 cm spicluted tumor with three fingers, Stage 2B
Sentinal node biopsy and lymph node removal with 3/18 positive in October 2007
4 TAC infusions
lumpectomy March 2008, bad margins
Re-excision on June 3rd, 2008 with clean margins
Fitted for compression sleeve July 16, 2008
Started the first of two TCH infusions August 14, 2008
Done with chemo and now a member of the blue dot club 9/17/08
Starting radiation October 1, 2008
life is still on hold
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Old 08-10-2009, 04:21 PM   #3
Bill
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Re: My Sis has her fourth AC Friday.

Hi Barb! Your sister is truly blessed to have you in her life. My wife, Nikki, had Taxol, Herceptin, and Tykerb at the same time. She really didn't have much trouble with the Taxol and Herceptin part. She had treatments on Friday, and just slept and rested a little more and felt a little achier over the weekend. I'm sorry I can't help more.
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Old 08-10-2009, 05:07 PM   #4
ammebarb
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Re: My Sis has her fourth AC Friday.

Thank you so much for responding. We had the opportunity to ask a zillion questions of her oncologist on Friday, and are really hoping that she tolerates the Taxol and Herceptin a bit better than she did the AC. Apparently, administration of a weekly lower dose than would be given on a three week cycle helps with the side effects. I came back to my own home as day earlier than I expected because she seemed to be doing ok on this last AC. She is really, really tired and had a little break through nausea and plenty of dry mouth, but is very relieved that this part of the regimen is done.

She'll do three weekly doses of Taxol and Herceptin, then have a week off, before repeating this cycle until she has twelve Taxols.

Thanks for being so wonderfully supportive. It has really helped to have you all reading and writing. God bless!

Barb A.
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Old 08-10-2009, 11:18 PM   #5
Savta
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Re: My Sis has her fourth AC Friday.

Hi, there!

Really, the worst is over. Taxol and herceptin are a walk in the park compared to AC. There are some side effects, but nothing that will really knock you out like the AC.
As far as having a companion along during the next 12--the biggest problem I had was feeling woozy from the anti-allergy medicine they gave me Apparantly, Taxol sometimes gives off an allergic reaction, so they gave me stuff to counteract that. I also got some steriods that kind of kept me like the energizer rabbit for the first two days. And I never felt the common side effects of the taxol until I was almost done.
Go out and celebrate. You're past the first step!
All the best!!
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Old 08-10-2009, 11:18 PM   #6
rl2
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Re: My Sis has her fourth AC Friday.

I did the taxol/herceptin regimen every 3 weeks. In a way it was easier than A/C, but I found that I had a lot of bone and joint pain, especially in my lower body, which would start about 48 hours after the taxol infusion and would last about 3 days (so I had it on Weds, by Friday I was in pain, and then in bed with painkillers for the weekend). And it was quite painful. I'm not sure how many people get that side effect or if it would be less likely to occur on a weekly schedule - maybe you know by now, but I needed help for those few days.
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Old 08-12-2009, 11:28 AM   #7
Believe51
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Re: My Sis has her fourth AC Friday.

Whew, now that this is over things are going to get better for her. Besides, with a sister like you how can she go wrong? You two are quite the team and I think of you both during the course of the zillion fleeting thoughts during my day. Thank Sis personally for me, I thank her for sharing her journey with us. She has really grown on me, along with you Dearie.>>Believe51
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9/7/06Husband 50yrs=StageIV IBC/HER2+,BoneMets10/06TaxotereX10,'H'1X wk,Zometa,Tamoxifen4/12/07Last Tax5/18/07Pet=Rapid Cell Activity,No Organ Mets,Lytic Lesions,Degeneration,Some Bone Repair5/07ChemoFail6/01/07Pleural Thoracentisis=Effusions,NoMalignantCells6/19/07+7/2/07DFCI
6/25/07BrainMRI=BrainMets,Many<9mm7/10/07WBR/PelvisRad37.5Gx15&Nutritionist8/19/07T/X9/20/07BrainMRI=2<2mm10/6/07Pet=BoneProgression
10/24/07ChemoFail11/9/07A/Cx10,EndTam12/7/07Faslodex12/10/07Muga7512/13/07BlasticLesions1/7/08BrainMRI=Clear4/1/08Pet=BoneImprovement,
NoProgression,Stable4/7/08BrainPerfect5/16/08Last A/C8/26/08BrainMets=10(<9mm)9/10/08Gamma10/30/08Met=5mm12/19/08Gamma5mets5
12/22/08SpinalMets1/14/09SpinalRads2/17/09BrainMRI=NoNewMets4/20/09BoneScan5/14/09Ixempra6/1/09BrainMRI=NumerousMets6/24/09DFCIw/DrBurstein6/26/09Continue
Ixempra/Faslodex/Zometa~TM now lower7/17/09Stop Ixempra By Choice9/21/09HOSPICE10/16/09Earned His Deserved Wings And Halo=37 Month Fight w/Stage 4 IBC, Her2+++,My Hero!!
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Old 08-20-2009, 09:18 AM   #8
suzan w
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Re: My Sis has her fourth AC Friday.

good for your sister...I was so sick after my 4th A/C that my onc said no more...it is rugged stuff, but works!!!
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Suzan W.
age 54 at diagnosis
5/05 suspicious mammogram-left breast
5/05 biopsy-invasive lobular carcinoma with LCIS,8mm tumor,stage 1 grade 2, ER+ PR+ Her2+++
6/14/05 bilateral mastectomy, node neg. all scans neg.
Oncotype DX-high risk
8/05-10/05 4 rounds A/C
10/05 -10/06 1 yr. herceptin
arimidex-5 years
2/14/08 started daily self administered injections..FORTEO for severe osteoporosis
7/28/09 BRCA 1 negative BRCA2 POSITIVE
8/17/09 prophylactic salpingo-oophorectomy
10/15/10 last FORTEOinjection
RECLAST infusion(ostoeporosis)
6/14/10 5 year cancerversary!
8/2010-18%increase in bone density!
no further treatments
Oncologist says, "Go do the Happy Dance"
I say,"What a long strange trip its been"
'One day at a time'
6-14-2015. 10 YEAR CANCERVERSARY!
7-16 to 9-16. Extensive (and expensive) dental work done to save teeth. Damage from osteoporosis and chemo and long term bisphosphonate use
6-14-16. 11 YEAR CANCERVERSARY!!
7-20-16 Prolia injection for severe osteoporosis
2 days later, massive hive outbreak. This led to an eventual dx of Chronic Ideopathic Urticaria, an auto-immune disease from HELL.
6-14-17 12 YEAR CANCERVERSARY!!
still suffering from CIU. 4 hospitilizations in the past year

as of today, 10-31-17 in remission from CIU and still, CANCER FREE!!!
6-14-18 13 YEAR CANCERVERSARY!! NED!!
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