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Old 11-17-2011, 01:28 PM   #1
AmyE
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Join Date: Apr 2011
Posts: 8
Mammaglobin-A DNA vaccine

Hello-
I'm waiting to hear if I meet the requirements, have passed one of them.
Have any of you heard of this? a short phase 1 trial. My oncologist thinks it will boost my immunity, although they state no medical benefits in the information sheet given to me. Link below, I appreciate any information!
(A bit nervous since this is a Phase 1)
thanks,
Amy
they are okay with me getting the Herceptin every 3 weeks, which I am.
I also take Arimidex daily, Xgeva every 6 weeks.
I am HER2+, ER+, PR+

This is a phase I open-label study to evaluate the safety and immunogenicity of a plasmid mammaglobin-A DNA vaccine. The plasmid mammaglobin-A DNA vaccine will be formulated as a naked plasmid DNA vaccine (WUSM-MGBA-01). The hypothesis of this study is that the mammaglobin-A DNA vaccine will be safe for human administration and capable of generating measurable CD8 T cell responses to mammaglobin-A. The primary objective of this study is to demonstrate the safety of the mammaglobin-A DNA vaccine. The secondary objective is to evaluate the immunogenicity of the mammaglobin-A DNA vaccine as measured by ELISPOT analysis, a surrogate for CD8 T cell function.


http://www.clinicalconnection.com/ex...05&slID=667230

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