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Old 12-05-2014, 06:53 PM   #1
Dakini52
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Join Date: Jan 2010
Location: Edmonds, WA
Posts: 202
Post CLEOPATRA for HER2

Wanted to pass along a new treatment that my oncologist discussed with me at a recent appointment. It is called CLEOPATRA and is the most current treatment for HER2 positive breast cancer. Here is a link that provides the information from the recent study:

http://www.esmo.org/Conferences/ESMO...-Breast-Cancer

Apparently it is considered to be the newest protocol for women with HER2 positive breast cancer.

Just wanted to pass it along for those who may be interested. I have been on Herceptin for 5 years and am trying to decide whether to add perjeta to my regime since I am in remission.
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Old 12-24-2014, 06:30 AM   #2
embur102
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Posts: 81
Re: CLEOPATRA for HER2

I am currently on this treatment plan for liver mets. (the brain mets are being treated separately). Had two treatments so far. I find it very rough...the extreme fatigue is the worst...I am down and out for about 7 days...have 4 more treatments to go. Supposed to be the first line "gold standard" ...we will see.

On a fun side note, my siblings had two special Cleopatra-style head coverings made for me, in honor of this study
__________________
Dx 4-12-2012
R unilat Mx 5-25-2012 (no reconstruction)
Stage 2B, Grade 3, Her2+++, Er + (15%), Pr -
4.2 cm, 2/14 nodes +
3 AC, 4 T/H
Zoladex 4 months
Oophorectomy Feb 2013
AI daily
Herceptin every 3 wks until Sept 2013
Gamma Knife June 2014, 2 cm brain met
Liver mets Oct 2014
Taxotere/herceptin/perjeta-CLEOPATRA trial Nov 2014-Mar 2015


"RISK BEING SEEN, IN ALL OF YOUR GLORY!" Jim Carrey
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Old 12-26-2014, 12:16 AM   #3
StephN
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Location: Misty woods of WA State
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Wink Re: CLEOPATRA for HER2

Embur -
Possible to show us a photo of you in one of your Cleopatra head coverings? Wonderful idea!
__________________
"When I hear music, I fear no danger. I am invulnerable. I see no foe. I am related to the earliest times, and to the latest." H.D. Thoreau
Live in the moment.

MY STORY SO FAR ~~~~
Found suspicious lump 9/2000
Lumpectomy, then node dissection and port placement
Stage IIB, 8 pos nodes of 18, Grade 3, ER & PR -
Adriamycin 12 weekly, taxotere 4 rounds
36 rads - very little burning
3 mos after rads liver full of tumors, Stage IV Jan 2002, one spot on sternum
Weekly Taxol, Navelbine, Herceptin for 27 rounds to NED!
2003 & 2004 no active disease - 3 weekly Herceptin + Zometa
Jan 2005 two mets to brain - Gamma Knife on Jan 18
All clear until treated cerebellum spot showing activity on Jan 2006 brain MRI & brain PET
Brain surgery on Feb 9, 2006 - no cancer, 100% radiation necrosis - tumor was still dying
Continue as NED while on Herceptin & quarterly Zometa
Fall-2006 - off Zometa - watching one small brain spot (scar?)
2007 - spot/scar in brain stable - finished anticoagulation therapy for clot along my port-a-catheter - 3 angioplasties to unblock vena cava
2008 - Brain and body still NED! Port removed and scans in Dec.
Dec 2008 - stop Herceptin - Vaccine Trial at U of W begun in Oct. of 2011
STILL NED everywhere in Feb 2014 - on wing & prayer
7/14 - Started twice yearly Zometa for my bones
Jan. 2015 checkup still shows NED
2015 Neuropathy in feet - otherwise all OK - still NED.
Same news for 2016 and half of 2017. Boring ...
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