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Old 11-25-2014, 09:54 AM   #1
'lizbeth
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Post Effect of Aspirin and Omega-3 Fatty Acids on COX-2 Protein Levels

NEW Effect of Aspirin and Omega-3 Fatty Acids on COX-2 Protein Levels in Post-Menopausal Women
A Phase 0, Investigator Initiated Study, Evaluating the Impact of COX2 Inhibition on Human Sera Biomarkers From Obese Subjects (NCT02062255)

Summary
Postmenopausal women who are overweight are at increased risk of developing hormone-sensitive breast cancer. Scientists think this may be because obesity is linked to chronic inflammation. The cyclooxygenase-2 (COX-2) protein and the COX-2 pathway have been found to play a role in this inflammation. Previous studies suggest that aspirin and omega-3 fatty acids may reduce the risk of hormone-sensitive breast cancer by blocking the COX-2 pathway. This study is looking at the effect that aspirin and/or an omega-3 fatty acid supplement has on COX-2 protein levels in postmenopausal women (at any weight) who have or have not been diagnosed with breast cancer.
This is a Phase O trial

Participation TimeNumber of visits unavailable, over 1 month
Participating research sitesNearest research site: San Antonio, TX; 1,122 miles from 92100; 1 site total Contact information
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