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Old 10-22-2013, 02:39 AM   #1
dawny
Senior Member
 
Join Date: Oct 2011
Location: Geelong, Australia
Posts: 250
Progression. :(

Hi my friends

I was on the TDM-1 trial here in Australia, now kicked to the curb.

I was diagnosed at stage 1V, and went straight to chemo, I had a complete response, so onc recommended against mastectomy. No rads either. I was NED for about six months before another breast lump, I then had lumpectomy and axillary dissection, whilst still only on Herceptin. After another four months, lymph nodes in my sternum reappeared, so I started TDM-1. Stable after first scans, but now another breast lump and lymph nodes.

So, I am thinking rads for sternum lymph nodes (not bone mets) and mastectomy. Thus holding on to chemo for another time, what do you think? I could start chemo now instead, but as it keeps coming back in the same spots, maybe local treatment will do the trick?

I am trying to stay positive, and I realize this is probably standard treatment for early stage, but not necessarily stage 1V.

If all goes to plan ( I am yet to have a brain ct, as that was left off the appointment list) I will be NED for Christmas! That's positive thinking for ya, right?

Sorry, this turned a little long winded, thanks for listening, and any feedback anyone would like to give

Dawn xx
__________________
Dx May 27 2011, age 43
Stage 1V 3.6cm breast lump, spot on lungs, nodes chest + neck
HER2+ ER/PR-
Abraxane weekly - 16 weeks
Herceptin every third week
September 26 2011 N.E.D!
Herceptin ongoing
8th Dec 2011 Brain MRI - clear
20th Dec 2011 bone/cat scan clear still NED
April 2012 scans show axillary node lump - ? what to do...
June 2012 Axillary node dissection 1/11 nodes affected, a wide local excision shows DCIS. Now what to do again? Watch and scan 3 monthly
April 2013, two spots in nodes to chest wall, start TDM1 (Kadcycla) as part of clinical trial
July 2013 stable
Oct 2013 progression off TDM-1 (Kadcycla)
Nov 2013 radiation to lymph nodes in sternum
Dec 2013. Mastectomy right side, pathology shows tumour was HER-2 negative, no wonder TDM-1 (Kadcycla) didn’t work!
April 2014 NED. On Herceptin only
August 2014 NED. On Herceptin only
March 2015. NED. On Herceptin only
September 2015 NED on Herceptin only
March 2016. Pulmonary embolism, Clexane injections daily forever. Still NED On Herceptin only
Nov 2016. Bone Mets in ribs - Radiation. Don’t know if bone Mets are er-/pr-/HER2+ or triple negative.
Can’t give self injections on to tablets (Xarelto) for blood clots.
2017 NED - On Herceptin only
2018 NED - On Herceptin only
2019 NED - On Herceptin only
2020 NED - On Herceptin only
2021 NED - On Herceptin only
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