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Old 09-02-2006, 12:23 AM   #1
Chelee
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Location: Southern, CA
Posts: 2,511
Estradiol level?

I had a FSH and it came back at 22 so my onc said she would put me on Femara. I mentioned to her the other cancer center said I should be on Tamoxifen since they felt I was peri-menopausal before I started chemo. (Which they are right, I was peri-meno.) My onc said instantly "Tamoxifen WILL bring your cancer back!" She was serious. She said I have to be on Femara.

Since my FSH results were 22, my onc said that it was "close enough" to be considered menopausal? I asked what the # SHOULD be at? She said they like you to be 20 or lower...but 22 is "good enough" for Femara?

(Well I read Femara doesn't do you any good if you aren't completely in menopause?) But in all honesty, I don't know? I mentioned my concern about Femara if I was NOT fully into menopause. So she ordered a drug called "Zoladex". She said it was to shut down my ovaries.

I have heard of Lupron, but not Zoladex? Is one better then another? And is 22 really LOW enough to have Femara work *without* Zoladex? Because if she is right...I rather NOT have the Zoladex. Any time I can NOT add another drug to my body...I am happy. But I don't want to take the femara if I am NOT really menopausal. Anyone have any info on this or can point me in a direction.

How come I have only heard of Lupron and NOT Zoladex...is it new? Sorry for all the questions.

Chelee
__________________
DX: 12-20-05 - Stage IIIA, Her2/Neu, 3+++,Er & Pr weakly positive, 5 of 16 pos nodes.
Rt. MRM on 1-3-06 -- No Rads due to compromised lungs.
Chemo started 2-7-06 -- TCH - - Finished 6-12-06
Finished yr of wkly herceptin 3-19-07
3-15-07 Lt side prophylactic simple mastectomy. -- Ooph 4-05-07
9-21-09 PET/CT "Recurrence" to Rt. axllia, Rt. femur, ilium. Possible Sacrum & liver? Now stage IV.
9-28-09 Loading dose of Herceptin & started Zometa
9-29-09 Power Port Placement
10-24-09 Mass 6.4 x 4.7 cm on Rt. femur head.
11-19-09 RT. Femur surgery - Rod placed
12-7-09 Navelbine added to Herceptin/Zometa.
3-23-10 Ten days of rads to RT femur. Completed.
4-05-10 Quit Navelbine--Herceptin/Zometa alone.
5-4-10 Appt. with Dr. Slamon to see what is next? Waiting on FISH results from femur biopsy.
Results to FISH was unsuccessful--this happens less then 2% of the time.
7-7-10 Recurrence to RT axilla again. Back to UCLA for options.
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Old 09-02-2006, 07:01 AM   #2
Yorkiegirl
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OK, I know that my FSH level was 62, and that meant that I was in menapause.


The higher the number for FSH means menapause.
Follicle-stimulating hormone (FSH) Menstruating women

(follicular or luteal phase):

5–20 international units per liter (IU/L)

(midcycle peak):

30–50 IU/L

Women past menopause:

Greater than 50 IU/L




My Estrodiol level was 6 , the lower the number means menapause.

Normal Values Estrodiol

Female (premenopausal): 20 to 400 pg/ml

Female (postmenopausal): 5 to 25 pg/ml
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Vicki
Texas
Biopsy Dx'd 3-23-05 Age 48
MRM 4-5-05 w/ 2 tumor's 5cm, and 6 cm (right side)
IDC (poorly differentiated infiltrating ductual carcinoma)
5+/16 nodes
Stage III A
Grade 3
ER/PR-, Her2/neu ++
Ki67 78%
Begin Chemo 5-2-05 4XAC Dose Dense , 4X Abraxane Dose Dense (ended August 05)
28 Rad's ended October 13 2005
Started Herceptin Weekly August 2005 for one year
Had a Simple mastectomy left side after Mamo showed incresed micro-calcifications. Jan. 17 2006.
Brain MRI Feb.2006--All Clear
August 28, 2006 Last Weekly Herceptin.
October 2006--Colonoscopy, 6 Polyp's removed--all B9
PET Scan July 2007
Abdominal MRI Oct. 2007---2 Right Kidney Cysts
Core Biopsy-- Lump on Scar Line 1-10-08---B9
Brain MRI 6-2008--All Clear
PET/CT Scan 6-2008
Sept. 8 2008, 4CM area removed from mastectomy scar line. Proved to be B9.
PET/CT Scan-- July 2009 --All clear
August 17,2009 ---Had Port Removed
6 Years NED -- April 5,2011
DX'd with Melanoma left arm 10-10-2011
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Old 09-02-2006, 11:57 PM   #3
Chelee
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Join Date: Feb 2006
Location: Southern, CA
Posts: 2,511
Yorkiegirl, Thanks for your reply. Its much appreciated...more then you know.

Chelee
__________________
DX: 12-20-05 - Stage IIIA, Her2/Neu, 3+++,Er & Pr weakly positive, 5 of 16 pos nodes.
Rt. MRM on 1-3-06 -- No Rads due to compromised lungs.
Chemo started 2-7-06 -- TCH - - Finished 6-12-06
Finished yr of wkly herceptin 3-19-07
3-15-07 Lt side prophylactic simple mastectomy. -- Ooph 4-05-07
9-21-09 PET/CT "Recurrence" to Rt. axllia, Rt. femur, ilium. Possible Sacrum & liver? Now stage IV.
9-28-09 Loading dose of Herceptin & started Zometa
9-29-09 Power Port Placement
10-24-09 Mass 6.4 x 4.7 cm on Rt. femur head.
11-19-09 RT. Femur surgery - Rod placed
12-7-09 Navelbine added to Herceptin/Zometa.
3-23-10 Ten days of rads to RT femur. Completed.
4-05-10 Quit Navelbine--Herceptin/Zometa alone.
5-4-10 Appt. with Dr. Slamon to see what is next? Waiting on FISH results from femur biopsy.
Results to FISH was unsuccessful--this happens less then 2% of the time.
7-7-10 Recurrence to RT axilla again. Back to UCLA for options.
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