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Old 02-04-2009, 11:42 AM   #1
Carolyns
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Xeloda Side Effects

Greetings smart friends,

I start Xeloda tomorrow and am looking for advise on how to prevent side effects. First I wonder about nausea - I seem to get it easily and this medicine is taken for 2 weeks. Recently on Navelbine I used Aloxi and it worked for three days and that worked fine. Now (if I get nausea) what do I do and for how long? I got a prescription for Zofran and am going to buy ginger tea. Any thoughts or advise? Anyone usually get nausea and found that the did not have a problem with Xeloda?

I will be combining it with Tykerb. I have been on Tykerb once in combination with Herceptin and did not have much trouble there. So I am mainly concerned about Xeloda.

Thanks in advance for sharing your words of wisdom.

Carolyn
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Old 02-04-2009, 03:45 PM   #2
Sheila
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Carolyn
I never have taken Tykerb, but I took Xeloda for over a year and had no problems whatsoever...it was combined with Herceptin...I was on 2500mg a day...I believe this is the new standard...some onc. still want to use 4000 mg a day...so if you get that dose and have side effects, it can be reduced and still work. I took 1500 in the morning and 1000 at night...i believe Brenda was on Tykerb Xeloda....hopefully she will see this and reply. Good luck to you!
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Diagnosed at age 49.99999 2/21/2002 via Mammography (Calcifications)
Core Biopsy 2/22/02
L. Mastectomy 2/25/2002
Stage 1, 0.7cm IDC, Node Neg from 19 nodes Her2+++ ER PR Neg
6/2003 Reconstruction W/ Tissue Expander, Silicone Implant
9/2003 Stage IV with Mets to Supraclavicular nodes
9/2003 Began Herceptin every 3 weeks
3/2006 Xeloda 2500mg/Herceptin for recurrence to neck nodes
3/2007 Added back the Xeloda with Herceptin for continued mets to nodes
5/2007 Taken Off Xeloda, no longer working
6/14/07 Taxol/Herceptin/Avastin
3/26 - 5/28/08 Taxol Holiday Whopeeeeeeeee
5/29 2008 Back on Taxol w Herceptin q 2 weeks
4/2009 Progression on Taxol & Paralyzed L Vocal Cord from Nodes Pressing on Nerve
5/2009 Begin Rx with Navelbine/Herceptin
11/09 Progression on Navelbine
Fought for and started Tykerb/Herceptin...nodes are melting!!!!!
2/2010 Back to Avastin/Herceptin
5/2010 Switched to Metronomic Chemo with Herceptin...Cytoxan and Methotrexate
Pericardial Window Surgery to Drain Pericardial Effusion
7/2010 Back to walking a mile a day...YEAH!!!!
9/2010 Nodes are back with a vengence in neck
Qualified for TDM-1 EAP
10/6/10 Begin my miracle drug, TDM-1
Mixed response, shrinking internal nodes, progression skin mets after 3 treatments
12/6/10 Started Halaven (Eribulen) /Herceptin excellent results in 2 treatments
2/2011 I CELEBRATE my 9 YEAR MARK!!!!!!!!!!!!!
7/5/11 begin Gemzar /Herceptin for node progression
2/8/2012 Gemzar stopped, Continue Herceptin
2/20/2012 Begin Tomo Radiation to Neck Nodes
2/21/2012 I CELEBRATE 10 YEARS
5/12/2012 BeganTaxotere/ Herceptin is my next miracle for new node progression
6/28/12 Stopped Taxotere due to pregression, Started Perjeta/Herceptin
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Old 02-05-2009, 05:07 AM   #3
Pam P
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I was on xeloda for over 3 yrs. Mostly with herceptin, but with tykerb for the last year or so. I never got any nausea. My only complaint with xeloda was that I got the hand/foot syndrome where they were red, sore, sometimes the skin would split. If that happens ask to reduce your dose. I started on either 3500 or 4000 mg/day. I did drop to 3000 eventually. I know others have had good result on lower. If you have issues with your hand/feet, get some good moisturerizers & use them often. I thought xeloda was a very tolerable treatment - it didn't even feel like I was on chemo. I cried when I had to go back to an IV kind.
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7/01 AC, taxol; radiation
2/02 tamoxifen
9/02 stage IV bone mets femara
1/03 taxotere/herceptin/aredia
6/03 herceptin, aredia & faslodex
1/04 navelbine, herceptin, aredia
2/05 herceptin/aredia
7/05 xeloda/herceptin/aredia
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2/09 gemzar/herceptin/zometa
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10/09 navelbine/herceptin & zometa
2/10 herceptin & tykerb & zometa
4/10 add xeloda &aromasin
10/10 dx with dermatomyiositis triggered by cancer
11/10 restart herceptin, tykerb, zometa
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2/11 2nd surgery - rod in Left femur
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8/11 radiation to left femur 20 tx'
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Old 02-05-2009, 03:44 PM   #4
Rich66
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If you google xeloda and henna you will find a site that has a recipe for topical treatment of HF syndrome. Lotions seem to help but aggressively rubbing them in can worsen things. There is another complete thread here to search for
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