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08-15-2006, 07:19 AM
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#1
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Senior Member
Join Date: Jun 2006
Location: East Texas
Posts: 40
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Bone Fractures.
Has anyone else experienced bone fractures from treatment? I finished my chemo (FEC 100, Taxotere, Xeloda) with Herceptin in October and then continued Herceptin with mastectomy, and RADS finishing one year of Herceptin in June. In December, I tripped and fell and fractured my pelvis...then in June I tripped and fractured my elbow and some ribs...(Sort of clumsy after all this treatment). I had bone density scan and do have low bone density so am taking actonel and calcium...but none of this was a problem before. Just wondered if anyone knows if the drugs I've taken can reduce bone density? I just turned 60 so my age is certainly a factor, but my family history is that these problems don't show up for another 10 years or so.
thanks.
Peggy
__________________
Stage IIIC
Diagnosed 5/05
FEC100 x4, Taxotere/Xeloda X4 (both with Herceptin)
Mastectomy, Rads x33 Herceptin X 9
3 Years NED!
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08-15-2006, 08:15 AM
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#2
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Senior Member
Join Date: Mar 2006
Posts: 1,843
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Please see the posts on omega threes and bone density, and magnesium calcium and bone density.
You should be able to find them using the search facility above. Click on search and enter the search terms.
If you cannot find them please come back.
RB
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08-16-2006, 10:25 PM
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#3
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Senior Member
Join Date: Sep 2005
Posts: 26
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Yes, my onc says that chemo definitely causes bone density loss. I'm sure type of drugs would make a difference. I had AC/T (3 years ago) and he said it could take up to 3 years for my bone density to level out from the chemo and femara.
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08-17-2006, 06:07 AM
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#4
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Senior Member
Join Date: Jun 2006
Location: East Texas
Posts: 40
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Thanks
Thank you for giving me info about the Omega 3 ( I had been following the discussions but hadnt really related to bone density) and that chemo does cause bone density loss...now I just need to work on not tripping for 3 years!
Peggy
__________________
Stage IIIC
Diagnosed 5/05
FEC100 x4, Taxotere/Xeloda X4 (both with Herceptin)
Mastectomy, Rads x33 Herceptin X 9
3 Years NED!
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08-17-2006, 06:24 AM
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#5
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Senior Member
Join Date: Aug 2003
Location: Morris, IL
Posts: 3,507
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Peggy
I fractured a rib while sneezing...and on Herceptin only!
__________________
"Be kinder than necessary, for everyone you meet is fighting some kind of battle."
Hugs & Blessings
Sheila
Diagnosed at age 49.99999 2/21/2002 via Mammography (Calcifications)
Core Biopsy 2/22/02
L. Mastectomy 2/25/2002
Stage 1, 0.7cm IDC, Node Neg from 19 nodes Her2+++ ER PR Neg
6/2003 Reconstruction W/ Tissue Expander, Silicone Implant
9/2003 Stage IV with Mets to Supraclavicular nodes
9/2003 Began Herceptin every 3 weeks
3/2006 Xeloda 2500mg/Herceptin for recurrence to neck nodes
3/2007 Added back the Xeloda with Herceptin for continued mets to nodes
5/2007 Taken Off Xeloda, no longer working
6/14/07 Taxol/Herceptin/Avastin
3/26 - 5/28/08 Taxol Holiday Whopeeeeeeeee
5/29 2008 Back on Taxol w Herceptin q 2 weeks
4/2009 Progression on Taxol & Paralyzed L Vocal Cord from Nodes Pressing on Nerve
5/2009 Begin Rx with Navelbine/Herceptin
11/09 Progression on Navelbine
Fought for and started Tykerb/Herceptin...nodes are melting!!!!!
2/2010 Back to Avastin/Herceptin
5/2010 Switched to Metronomic Chemo with Herceptin...Cytoxan and Methotrexate
Pericardial Window Surgery to Drain Pericardial Effusion
7/2010 Back to walking a mile a day...YEAH!!!!
9/2010 Nodes are back with a vengence in neck
Qualified for TDM-1 EAP
10/6/10 Begin my miracle drug, TDM-1
Mixed response, shrinking internal nodes, progression skin mets after 3 treatments
12/6/10 Started Halaven (Eribulen) /Herceptin excellent results in 2 treatments
2/2011 I CELEBRATE my 9 YEAR MARK!!!!!!!!!!!!!
7/5/11 begin Gemzar /Herceptin for node progression
2/8/2012 Gemzar stopped, Continue Herceptin
2/20/2012 Begin Tomo Radiation to Neck Nodes
2/21/2012 I CELEBRATE 10 YEARS
5/12/2012 BeganTaxotere/ Herceptin is my next miracle for new node progression
6/28/12 Stopped Taxotere due to pregression, Started Perjeta/Herceptin
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08-17-2006, 10:04 AM
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#6
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Senior Member
Join Date: Sep 2005
Location: Maryland
Posts: 30
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I broke a bone in my foot, while walking across the street in rubber soled shoes (no heel)!
My bone density came back as severe osteoporosis of the spine, and moderate else where. I was started on Fosamax the next morning.
__________________
Margo
Diagnosed 08/2004 @ 45; Metaplastic Breast Cancer (MpBC)
Stage IV, HER2 3+, ER-/PR-, Met to Liver
08/2004 - Neo-adjuvant Taxotere/Carboplatin/Herceptin (TCH) - 4 rounds.
09/2004 - Herceptin - Weekly.
11/2004 - Liver RFA, followed w/TCH - 2 rounds.
12/2004 - Lumpectomy, axillary node dissection, followed w/TCH - 2 rounds.
05/2005 - Radiation - Breast, shoulder, neck (left side) - 35X
09/2005 - Developed severe osteoporosis - Boniva - monthly
04/2008 - Herceptin - Every 3 weeks (changed from weekly).
05/2012 - Mets: 3 new liver and 2 lymph nodes.
06/2012 - Start 16 rounds Navelbine and Herceptin weekly.
11/2012 - Liver resection, RFAs (8), lymphadenectomy (2), cholecystectomy.
12/2012 - Herceptin and Letrozole.
05/2014 - Mets: 5 aortocaval nodes & 1 mesenteric.
06/2014 - Herceptin/Perjeta/Taxotere - 6 rounds.
10/2014 - Herceptin / Perjeta - Open ended
04/2015 - Progression: Porta hepatic node, 2 aortocaval nodes.
05/2015 - Exploratory surgery treating progression, 12 nodes removed.
07/2015 - Restart Herceptin / Perjeta
01/2016 - Progression 8 nodes.
02/2016 - Starting T-DM1 (Kadcyla) - Open ended.
07/2017 - Progression.
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08-17-2006, 06:06 PM
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#7
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Senior Member
Join Date: Jun 2006
Location: East Texas
Posts: 40
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Oh my
Hmmm...no tripping, no sneezing, and no crossing the street....this may be an interesting 3 years.
Thanks for the info...it really helps to know that others are having as much fun as I am.
__________________
Stage IIIC
Diagnosed 5/05
FEC100 x4, Taxotere/Xeloda X4 (both with Herceptin)
Mastectomy, Rads x33 Herceptin X 9
3 Years NED!
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