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Old 07-29-2006, 04:12 PM   #1
margo
Senior Member
 
Join Date: Sep 2005
Location: Maryland
Posts: 30
Question PET Scan - False Postives

My PET/CT scan from last week shows that my liver looks great. I had an RFA, which has been successful. My liver SUV score has dropped to zero over time.

However, the SUV at my lumpectomy (w/shrinking hematoma) site are rising over time (1.4, 1.9, 2.4). Last week, my value was 2.4 and a comment of "Malignancy Not Excluded, further testing required". My surgeon and Oncologist seem to think this is a false positive. If so, why the rising score? My lumpectomy was in 12/04.

At surgical sites, is anyone else experiencing:

1. Rising SUV's?
2. Level SUV's?
3. SUV's slowly dropping and/or returning to zero?
__________________
Margo

Diagnosed 08/2004 @ 45; Metaplastic Breast Cancer (MpBC)
Stage IV, HER2 3+, ER-/PR-, Met to Liver

08/2004 - Neo-adjuvant Taxotere/Carboplatin/Herceptin (TCH) - 4 rounds.
09/2004 -
Herceptin - Weekly.
11/2004 - Liver RFA, followed w/TCH - 2 rounds.
12/2004 - Lumpectomy, axillary node dissection, followed w/TCH - 2 rounds.
05/2005 - Radiation - Breast, shoulder, neck (left side) - 35X
09/2005 - Developed severe osteoporosis - Boniva - monthly
04/2008 - Herceptin - Every 3 weeks (changed from weekly).
05/2012 - Mets: 3 new liver and 2 lymph nodes.
06/2012 - Start 16 rounds Navelbine and Herceptin weekly.
11/2012 - Liver resection, RFAs (8), lymphadenectomy (2), cholecystectomy.
12/2012 - Herceptin and Letrozole.
05/2014 - Mets: 5 aortocaval nodes & 1 mesenteric.
06/2014 - Herceptin/Perjeta/Taxotere - 6 rounds.
10/2014 - Herceptin / Perjeta - Open ended
04/2015 - Progression: Porta hepatic node, 2 aortocaval nodes.
05/2015 - Exploratory surgery treating progression, 12 nodes removed.
07/2015 - Restart Herceptin / Perjeta
01/2016 - Progression 8 nodes.
02/2016 - Starting T-DM1 (Kadcyla) - Open ended.
07/2017 - Progression.
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Old 07-29-2006, 06:30 PM   #2
heblaj01
Senior Member
 
Join Date: Apr 2006
Posts: 543
Margo,

If you suspect a false positive PET/CT scan results check if all precautions were taken at the time of the scan & the day before:
1. warm blanket : see http://her2support.org/vbulletin/sho...ht=warm+coffee

2. Prior day: no sugar, artificial sweeteners,fruits, carbohydrates. No exercize etc... (Precautions normally recommanded by radiology department)
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Old 07-29-2006, 08:25 PM   #3
margo
Senior Member
 
Join Date: Sep 2005
Location: Maryland
Posts: 30
PET Scans - False Positives

Thank you for the information about the warm blanket. I will pass it on to the Nuclear Medicine department. I was wrapped in a blanket, though it was not warmed.

The day before my test I was allowed to eat only chicken and broccoli, and no food after midnight. It is a good thing I like broccoli :-)

I am curious about my SUV's and the pattern that is occurring at the surgery site. Hopefully, I will receive some information from patients that are experiencing similar issues.

Thank you again,

Margo
__________________
Margo

Diagnosed 08/2004 @ 45; Metaplastic Breast Cancer (MpBC)
Stage IV, HER2 3+, ER-/PR-, Met to Liver

08/2004 - Neo-adjuvant Taxotere/Carboplatin/Herceptin (TCH) - 4 rounds.
09/2004 -
Herceptin - Weekly.
11/2004 - Liver RFA, followed w/TCH - 2 rounds.
12/2004 - Lumpectomy, axillary node dissection, followed w/TCH - 2 rounds.
05/2005 - Radiation - Breast, shoulder, neck (left side) - 35X
09/2005 - Developed severe osteoporosis - Boniva - monthly
04/2008 - Herceptin - Every 3 weeks (changed from weekly).
05/2012 - Mets: 3 new liver and 2 lymph nodes.
06/2012 - Start 16 rounds Navelbine and Herceptin weekly.
11/2012 - Liver resection, RFAs (8), lymphadenectomy (2), cholecystectomy.
12/2012 - Herceptin and Letrozole.
05/2014 - Mets: 5 aortocaval nodes & 1 mesenteric.
06/2014 - Herceptin/Perjeta/Taxotere - 6 rounds.
10/2014 - Herceptin / Perjeta - Open ended
04/2015 - Progression: Porta hepatic node, 2 aortocaval nodes.
05/2015 - Exploratory surgery treating progression, 12 nodes removed.
07/2015 - Restart Herceptin / Perjeta
01/2016 - Progression 8 nodes.
02/2016 - Starting T-DM1 (Kadcyla) - Open ended.
07/2017 - Progression.
margo is offline   Reply With Quote
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