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Re: Good News...Bad News...Okay News
Denise- I had a similar experience with my bone mets. My breast tumor was Her2+++, and ER-, but before I finished treatment it jumped to the bones. My doc suspected ER+ then but didn't biopsy the bone because (1) painful and (2) alot of false negatives do to the poor technique. Instead he dug up my lymph nodes from over a year prior, and had the + ones stained for estrogen receptors. Apparently they never check for ER status in lymph nodes- only in the primary tumor (breast). Anyway- the lymph nodes were like 98% positive for ER. So ta da! I really felt like God just threw me a bone (pun intended). Just something to think about- or talk to your doc about. 
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[B]Kristin
Aug 2010: diagnosed stage 3b, 4 mo. after birth of son. 29 yrs old and breastfeeding, ER/PR-, Her-2+ started Neoadjuvant therapy: 4x FEC, 10x abraxane & Herceptin
Feb 2011: L mx with recon. Path. showed only DCIS but 4/10+ nodes.
March 2011: 6 wks rads.
Mother passed, lower back pain.
Late May 2011: Bone mets but organs clear; Tykerb, Xeloda, Xgeva. Stopped Herceptin. Implant infected: removed implant.
October 2011: Bone progression; Gemzar and Carboplatin & restarted Herceptin.
Jan 2012: Progression, re-classified as ER+; Tykerb, Herceptin, Zoladex & Femara. Anti-E is working!
May 2012: ovaries out, markers stable but elevated. Cont. Herceptin, Tykerb, Xgeva & Femara.
Dec 2012: aromasin
Jan 2013: faslodex, herceptin, tykerb
Jun: Kadcyla
Aug: Rads to hip, then Perjeta, Herceptin & Taxotere
Nov 2013: Perjeta, Herceptin, Halaven
Early 2014: Affinitor, Aromasin, Perjeta, Herceptin.
June 2014: Estradiol, Perjeta, Herceptin
Aug 14: Tamoxofin, H & P
http://kristin-notdying-blog.blogspot.com/
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