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Old 02-19-2016, 06:24 PM   #1
PMK
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Join Date: Dec 2015
Posts: 11
Herceptin/Perjeta only

Hello,
I have been on Herceptin/ Perjeta (only) for 3 months. I was wondering if anyone else has only been on these antibodies dx with stage IV, and what the results were. Or, how long did it last. I am not happy with waiting for things to progress before adding something. I feel like I should be doing more.
Dx Stage IV Her +, April 2015 with collapsed lung-mets to lung, liver, questionable bone, and some nodes
Chest tube placed to relieve 5 liters of fluid in right lung
1 round of cyclophosphamide/doxorubicin until tumor biopsy confirmed Her2+
May 2015-began taxol/herceptin/perjeta
chest tube removed
3 lung taps to remove continued fluid problem and shortness of breath
September 2015- plural tube placed in lung
Continued with taxol/herceptin/perjeta
Scans slowly improved
December 2015-discontinue Taxol due to increased neuropathy in feet and hands
February 2016-plorax drain removed, fluid issue resolved. Bottom of right lung remains collapsed, but feels ok.
Continuing on herceptin/perjeta
(lost 5 year old daughter to neuroblastoma in 2011 after a 2.5 year battle)
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Old 02-19-2016, 07:01 PM   #2
Pamelamary
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Join Date: Apr 2012
Location: Melbourne, Australia
Posts: 494
Re: Herceptin/Perjeta only

Dear PMK,
There are many of us stage IV women who remain stable on just the anti-Her2 drugs. As the side effects are more tolerable, relax and enjoy the break. May it last a very long time.
Regards..... Pam
__________________
Diagnosed 2004: Lumpectomy - 2 tumours, both grade 1 infiltrating duct carcinoma, about 12mm. ER+,
C-erbB-2 status 3+.
Clear margins, no nodal involvement.
Radiotherapy, i year Tamoxifen, 4 years Arimidex.
Rediagnosed 2012: Multiple bone metastases.
3/12: began on Marianne trial - T-DM1 + Pertuzamab/Placebo.
5/12:Unexpected development of numerous bilateral liver mets. Came off trial.
Started Docetaxol/ Herceptin + Zometa.
8/12:Bones stable +major regression in liver (!)
9/12:Can't take any more Docetaxol! Start on Herceptin and Tamoxifen. Cross fingers!
Changed to Denosumab.
11/12: Scan shows stable - yay!
11/13: Still stable :-) !!!
1/16: All stable, but lowered calcium, so switched to Zometa 3 monthly.
2/19: Happily still stable on Herceptin, Letrozole and 3 monthly Zometa.
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