higher vit D levels weakly assoctd w reduced bc risk, highly assocd w better survival

[Lani]

although not her2 subtype specific here is the article abstract:
Epidemiology
British Journal of Cancer 110, 2772-2784 (27 May 2014) | doi:10.1038/bjc.2014.175

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Y Kim
Y Je
Vitamin D intake, blood 25(OH)D levels, and breast cancer risk or mortality: a meta-analysis

Y Kim and Y Je

Abstract
Background:

Experimental studies suggest potential anti-carcinogenic properties of vitamin D against breast cancer risk, but the epidemiological evidence to date is inconsistent.

Methods:

We searched MEDLINE and EMBASE databases along with a hand search for eligible studies to examine the association between vitamin D status (based on diet and blood 25-hydroxyvitamin D (25(OH)D)) and breast cancer risk or mortality in a meta-analysis. A random-effect model was used to calculate a pooled adjusted relative risk (RR).

Results:

A total of 30 prospective studies (nested case-control or cohort) were included for breast cancer incidence (n=24 studies; 31 867 cases) or mortality (n=6 studies; 870 deaths) among 6092 breast cancer patients. The pooled RRs of breast cancer incidence for the highest vs the lowest vitamin D intake and blood 25(OH)D levels were 0.95 (95% CI: 0.88–1.01) and 0.92 (95% CI: 0.83–1.02), respectively. Among breast cancer patients, high blood 25(OH)D levels were significantly associated with lower breast cancer mortality (pooled RR=0.58, 95% CI: 0.40–0.85) and overall mortality (pooled RR=0.61, 95% CI: 0.48–0.79). There was no evidence of heterogeneity and publication bias.

Conclusions:

Our findings suggest that high vitamin D status is weakly associated with low breast cancer risk but strongly associated with better breast cancer survival.

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British Journal of CancerISSN: 0007-0920EISSN: 1532-1827© 2014 Cancer Research UK

[LeahM]

Last fall my PCP checked my D levels and they were extremely low. I am now on high doses of D and will get levels checked again soon. I can say this tho, I "feel" better now then I did before.
I printed out a similar study and shared it with my onc. Have a copy for PCP too.
Thanks Lani!