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Old 03-18-2008, 07:39 AM   #1
TSund
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Location: DFW area (TX)
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Re: "The Making of Herceptin" and skin mets

Can someone help?

Lolly has been on my mind and my copy of the book was loaned out . I am recalling someone in that book that treated skin mets successfully with an injection straight into the mets. I know the book is dated at this point, but the treatment was something not standardly used for breast cancer skin mets, and I don't know if it's something that has been further explored or not.

SOMEONE out there please help. Thanks!!

TRS
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Terri, spouse of Ruth, Dallas/Ft. Worth area
Ruth dx 05/01/07 (age 50) Filipino
multifocal, several tumors .5 -2.5 cm, large area
Breast MRI showed 2 enlarged nodes, not palpable
100%ER+, 95%PR+, HER2+++
6x pre-surgery TCH chemo finished 9/15/7 Dramatic tumor shrinkage
1 year Herceptin till 6/08
MRM 10/11/07, SNB: 0/4 nodes + Path: tumors reduced to only a few "scattered cells"
now 50% ER+, PR- ???
Rads finished 1/16/08
Added Tamoxifen,
Finished Herceptin 05/08
NOW is the time to appreciate life to the fullest.
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Old 03-18-2008, 09:40 AM   #2
Lani
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haven't read the book but have heard Dr Slamon and Dr Pegram lecture

I seem to remember pictures of both herceptin melting skin mets and/or the combination of herceptin and avastin doing so. These were slides used to show great results, not necessarily what happened to every patient.

Will be attending several conferences soon--will tune up my eyes and ears.
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Old 03-18-2008, 10:41 AM   #3
TSund
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Lani, was that local injections or regular Herceptin infusion? In the book the woman I was thinking of WANTED to try Herceptin injection into the skin mets but couldn't get approval, so ended up doing something entirely different.

TRS
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Terri, spouse of Ruth, Dallas/Ft. Worth area
Ruth dx 05/01/07 (age 50) Filipino
multifocal, several tumors .5 -2.5 cm, large area
Breast MRI showed 2 enlarged nodes, not palpable
100%ER+, 95%PR+, HER2+++
6x pre-surgery TCH chemo finished 9/15/7 Dramatic tumor shrinkage
1 year Herceptin till 6/08
MRM 10/11/07, SNB: 0/4 nodes + Path: tumors reduced to only a few "scattered cells"
now 50% ER+, PR- ???
Rads finished 1/16/08
Added Tamoxifen,
Finished Herceptin 05/08
NOW is the time to appreciate life to the fullest.
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Old 03-18-2008, 05:18 PM   #4
Lani
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Posts: 4,778
it was

regular infusions
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