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Old 03-28-2007, 07:59 AM   #1
panicked911
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arimidex and high cholesterol

Of the few of us who are taking arimidex or aother of the AI's, has anyone noticied a large increase in their cholesterol levels? I have been on arimidex 15 months and my cholesterol, particularly the LDL is up by 1/3 .
I am a vegetarian who exercises regularly so diet and lack of exercise are not the culprit - it is not hereditory either.
Onc says that AI's can do it but lets see what happens.
I am going to be retested again but I am wondering if anyone else has gone through this and what are the options and/or suggestions

thanks,


Susanne
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Old 03-28-2007, 08:10 AM   #2
suzan w
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I have had high cholesterol for years...and my doctors have always been puzzled...calling it "hereditary"...well, I am the only one in my family with high cholesterol (and cancer...) and I really have always watched what I eat, anyway, I was told that chemo, as well as arimidex can raise one's cholesterol. Sure enough, mine went up when I started chemo. So, when chemo ended I started taking meds for that. There definitely is a connection I think.
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Suzan W.
age 54 at diagnosis
5/05 suspicious mammogram-left breast
5/05 biopsy-invasive lobular carcinoma with LCIS,8mm tumor,stage 1 grade 2, ER+ PR+ Her2+++
6/14/05 bilateral mastectomy, node neg. all scans neg.
Oncotype DX-high risk
8/05-10/05 4 rounds A/C
10/05 -10/06 1 yr. herceptin
arimidex-5 years
2/14/08 started daily self administered injections..FORTEO for severe osteoporosis
7/28/09 BRCA 1 negative BRCA2 POSITIVE
8/17/09 prophylactic salpingo-oophorectomy
10/15/10 last FORTEOinjection
RECLAST infusion(ostoeporosis)
6/14/10 5 year cancerversary!
8/2010-18%increase in bone density!
no further treatments
Oncologist says, "Go do the Happy Dance"
I say,"What a long strange trip its been"
'One day at a time'
6-14-2015. 10 YEAR CANCERVERSARY!
7-16 to 9-16. Extensive (and expensive) dental work done to save teeth. Damage from osteoporosis and chemo and long term bisphosphonate use
6-14-16. 11 YEAR CANCERVERSARY!!
7-20-16 Prolia injection for severe osteoporosis
2 days later, massive hive outbreak. This led to an eventual dx of Chronic Ideopathic Urticaria, an auto-immune disease from HELL.
6-14-17 12 YEAR CANCERVERSARY!!
still suffering from CIU. 4 hospitilizations in the past year

as of today, 10-31-17 in remission from CIU and still, CANCER FREE!!!
6-14-18 13 YEAR CANCERVERSARY!! NED!!
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Old 03-28-2007, 10:01 AM   #3
Cynthia
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Count me in. My cholesteral use to be in the 150's. After starting Arimidex and Herceptin it jumped to 230. Neither my oncologist nor family doctor thought there was a link to the Herceptin or AI, but I'm not at all convinced. I am now on Lipitor.
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Diagnosed 9/03 @ 43 years (pre-menopausal)
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4 nodes +; High Grade
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Bilateral Mastectomy; Reconstruction
CAF x 6; Radiation; One Year Late Herceptin
Oophorectomy; Arimidex
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Old 03-28-2007, 10:27 AM   #4
Becky
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High cholestrol is a listed side effect on Arimidex's label. It is also a side effect for Femara. It is thought it is not a problem for Aromosin as it works in different method.


My mother, cousin and friend - all on Arimidex, have this problem and were put on Lipitor. I do not have this problem.
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Found lump via BSE
Diagnosed 8/04 at age 45
1.9cm tumor, ER+PR-, Her2 3+(rt side)
2 micromets to sentinel node
Stage 2A
left 3mm DCIS - low grade ER+PR+Her2 neg
lumpectomies 9/7/04
4DD AC followed by 4 DD taxol
Used Leukine instead of Neulasta
35 rads on right side only
4/05 started Tamoxifen
Started Herceptin 4 months after last Taxol due to
trial results and 2005 ASCO meeting & recommendations
Oophorectomy 8/05
Started Arimidex 9/05
Finished Herceptin (16 months) 9/06
Arimidex Only
Prolia every 6 months for osteopenia

NED 18 years!

Said Christopher Robin to Pooh: "You must remember this: You're braver than you believe and stronger than you seem and smarter than you think"
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