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Old 07-03-2009, 01:20 PM   #1
StephN
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Lightbulb "If you have had radiation"

"you should be more aware of that area as radiation will make it more prone to skin cancers."
Quote from my dermatologist yesterday.

She said she often sees spots that do not look like they are anything to us because we are noticing the places that stand out more on our skin. Such as Keratoses, which are raised rust color areas of the skin, but benign. What she noticed was what may be a basal cell carcinoma just inside my radiated quadrant. I had not noted that spot. She sprayed it and will check in 3 months.

I also had a place removed on my left shoulder blade that is nowhere near my radiated area. It is being biopsied. The main reason I noticed that one is that it lies right under my bra strap which can irritate it at times.

Just wanted to mention this as I don't recall "being more prone to skin cancers" being on my info for my radiation treatment. Just something else to place on our list of "Things to be Vigilant About."
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"When I hear music, I fear no danger. I am invulnerable. I see no foe. I am related to the earliest times, and to the latest." H.D. Thoreau
Live in the moment.

MY STORY SO FAR ~~~~
Found suspicious lump 9/2000
Lumpectomy, then node dissection and port placement
Stage IIB, 8 pos nodes of 18, Grade 3, ER & PR -
Adriamycin 12 weekly, taxotere 4 rounds
36 rads - very little burning
3 mos after rads liver full of tumors, Stage IV Jan 2002, one spot on sternum
Weekly Taxol, Navelbine, Herceptin for 27 rounds to NED!
2003 & 2004 no active disease - 3 weekly Herceptin + Zometa
Jan 2005 two mets to brain - Gamma Knife on Jan 18
All clear until treated cerebellum spot showing activity on Jan 2006 brain MRI & brain PET
Brain surgery on Feb 9, 2006 - no cancer, 100% radiation necrosis - tumor was still dying
Continue as NED while on Herceptin & quarterly Zometa
Fall-2006 - off Zometa - watching one small brain spot (scar?)
2007 - spot/scar in brain stable - finished anticoagulation therapy for clot along my port-a-catheter - 3 angioplasties to unblock vena cava
2008 - Brain and body still NED! Port removed and scans in Dec.
Dec 2008 - stop Herceptin - Vaccine Trial at U of W begun in Oct. of 2011
STILL NED everywhere in Feb 2014 - on wing & prayer
7/14 - Started twice yearly Zometa for my bones
Jan. 2015 checkup still shows NED
2015 Neuropathy in feet - otherwise all OK - still NED.
Same news for 2016 and all of 2017.
Nov of 2017 - had small skin cancer removed from my face. Will have Zometa end of Jan. 2018.
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Old 07-03-2009, 01:36 PM   #2
Jackie07
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Thanks for the reminder, StephN. I had had many seborrheic karatoses removed in 2000 after they had sprung up following my infertility treatment. I insisted on getting them 'off my back' because one of the research article I found recommended it just in case they were 'actinic' karatoses being misidentified.

According the information from MedicineNet, "anywhere from 5%-10% of AKs can potentially go on to become skin cancers...While AKs may give rise to skin cancers like squamous cell carcinomas, they do not turn into melanomas. Nevertheless, it is important to keep in mind that people with AKs may be more prone to melanomas simply by having more sun damage."
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Last edited by Jackie07; 07-03-2009 at 01:44 PM..
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Old 07-03-2009, 02:54 PM   #3
Cannon
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Actually, I believe there is a general increased risk of melanoma for people who have had breast cancer. Still not a huge risk, but increased. I googled "breast cancer and melanoma" and got a number of studies that support this, and I didn't see any referencing the area of radiation.

So - caution as always!
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Dx 8/06 Age 43 Stage IIIA multifocal throughout breast, largest tumor 5 cm, grade 3, comedo, ER+PR+HER+++
Neoadjuvant A/C 4X Dose Dense
11/06 Bilateral Mastectomy (no choice on the right, my choice on the left)
Taxol+Herceptin weekly x12, continuing with Herceptin, finished one year in 12/07
33 Rads
Femara for 5+ years, staying on (started with Arimidex, switched after about a month, much happier)
Abnormal brain MRI shows no cancer, but "extensive white matter diease" - unknown cause
BRCA negative - lots of cancer in my family
survivor of thyroid cancer
also have Crohn's disease
CT and bone scan say NED as of 5/13
dx with severe cardiomyopathy 5/12 (likely due to chemo and Herceptin), ejection fraction in low 20's, now up to 40, went to 50, latest read 12/13 is back down to 35
1/13 Acute pancreatitis - are you kidding me?
9/13 started Humira for Crohn's. starting to have some energy again
B12 and Vit D both needed supplementation
Cataracts in both eyes noted 6/12 - surgery in the next 2-4 years?
4/14 Kidney stones/blockage/infection - related to Crohn's Disease
5/14 My aunt passed away - she was diagnosed after I was with Stage I - not Her2+, then Stage 4 for about one year
6/14 Scans - still NED, thank God. However, broken rib (I didn't notice) lots of bone degeneration osteopenia/osteoporosis. I also still have cardiomyopathy secondary to chemo.
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Old 07-21-2009, 03:03 PM   #4
StephN
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Good news !

Got my results back from my skin "thing" biopsy. It tested as BENIGN, thankfully. Seborrheic Keratoses, sometimes called barnacles, can be dangerous-looking but they are actually benign, probably 90% or more often.

The one I had that prompted the concern was on my shoulder blade and about the size of a dime. It had gotten irritated and had the look of a possible basal cell skin cancer. The tech who call me saw the photo they took prior to removal, and said she could see why the concern.

Another bullit dodged!

As Jackie mentioned, it is a good idea to become familiar with the things that grow on our skin. Or at least get anything that looks strange check out. There are several kinds of Keratoses alone!
__________________
"When I hear music, I fear no danger. I am invulnerable. I see no foe. I am related to the earliest times, and to the latest." H.D. Thoreau
Live in the moment.

MY STORY SO FAR ~~~~
Found suspicious lump 9/2000
Lumpectomy, then node dissection and port placement
Stage IIB, 8 pos nodes of 18, Grade 3, ER & PR -
Adriamycin 12 weekly, taxotere 4 rounds
36 rads - very little burning
3 mos after rads liver full of tumors, Stage IV Jan 2002, one spot on sternum
Weekly Taxol, Navelbine, Herceptin for 27 rounds to NED!
2003 & 2004 no active disease - 3 weekly Herceptin + Zometa
Jan 2005 two mets to brain - Gamma Knife on Jan 18
All clear until treated cerebellum spot showing activity on Jan 2006 brain MRI & brain PET
Brain surgery on Feb 9, 2006 - no cancer, 100% radiation necrosis - tumor was still dying
Continue as NED while on Herceptin & quarterly Zometa
Fall-2006 - off Zometa - watching one small brain spot (scar?)
2007 - spot/scar in brain stable - finished anticoagulation therapy for clot along my port-a-catheter - 3 angioplasties to unblock vena cava
2008 - Brain and body still NED! Port removed and scans in Dec.
Dec 2008 - stop Herceptin - Vaccine Trial at U of W begun in Oct. of 2011
STILL NED everywhere in Feb 2014 - on wing & prayer
7/14 - Started twice yearly Zometa for my bones
Jan. 2015 checkup still shows NED
2015 Neuropathy in feet - otherwise all OK - still NED.
Same news for 2016 and all of 2017.
Nov of 2017 - had small skin cancer removed from my face. Will have Zometa end of Jan. 2018.
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Old 07-21-2009, 03:33 PM   #5
Shobha
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Great news, Steph! I am so happy to hear your news. I have a small red raised spot under my armpit where I had my radiation. My surgeon told me to simply wait and watch it - she thinks it is a a ingrown hair or pimple. But it has been almost one month and it is still there...

I may just go see a dermatologist because no one else seems to know what it is.

hugs,
shobha
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DX: 06-30-2007 - left breast -stage IIIB, Her2/Neu 3+++, ER weakly positive, PR-
Taxol+herceptin weekly for 3 months
FEC+herceptin every 3 weeks for 3 months
BRCA 1 and 2 - Negative
Jan 2008 - Bilateral mastectomy, prophylactic Rt. side.
Radiation for 5 weeks
Completed my yr of herceptin on 07-14-2008
Brain MRI - 3/2/09 Clean
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Old 07-21-2009, 06:35 PM   #6
CLTann
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Please allow me to use this thread to talk about the hidden dangers of radiation. Of course, for many patients, there is no choice but to use it as a fighting tool. Although all medical personnels recognize the danger of cumulative radiation and all doctors know there is a finite quantity of radiation every person can tolerate for the lifetime, there is NO one adding up what you and I have been exposed. No one keeps track on how much you already used up the limit. They only warn you that you should limit your exposure but they kept ordering x ray, mammo, bone scan, cat scan, pet scan, radioactive dye, etc, etc, etc. Many patients die from the radiation overdose and did not know what killed them. Industrial labs and plants using radiation (nuclear reactor, for instance) require workers to wear badges that record the measurable radiation, on a cumulative basis. It is time the patients should have these cheap devices too.
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Stage 1 dx Sept 05
ER/PR positive HER2 +++ Grade 3
Invasive carcinoma 1 cm, no node involvement
Mastec Sept 05
Annual scans all negative, Oct 06
Postmenopause. Arimidex only since Sept 06, bone or muscle ache after 3 month
Off Arimidex, change to Femara 1/12-07, ache stopped
Sept 07 all tests negative, pass 2 year mark
Feb 08 continue doing well.
Sep 09 four year NED still on Femara.
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Old 07-21-2009, 06:53 PM   #7
Mary Jo
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Thanks for the info Steph and I was happy to read you had benign results.

Ann, thank you too for your concerns about our exposure to radiation. So much of what we endure is so toxic and God only knows what side effects many of us will endure from what we've gone through or continue to go through.

Thank you Ladies...

Mary Jo
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Dx. 6/24/05 age 45 Right Breast IDC
ER/PR. Neg., - Her2+++
RB Mast. - 7/28/05 - 4 cm. tumor
Margins clear - 1 microscopic cell 1 sent. node
No Vasucular Invasion
4 DD A/C - 4 DD Taxol & Herceptin
1 full year of Herceptin received every 3 weeks
28 rads
prophylactic Mast. 3/2/06

17 Years NED

<>< Romans 8:28
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Old 07-22-2009, 11:52 PM   #8
harrie
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Radiation can also make reconstruction a bit tougher, no pun intended. Not impossible, but can be more difficult since the skin is not as elastic.
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*** MARYANNE *** aka HARRIECANARIE

1993: right side DCIS, lumpectomy, rads
1999: left side DCIS, lumpectomy, rads, tamoxifen

2006:
BRCA 2 positive
Stage I, invasive DCIS (6mm x 5mm)
Grade: intermediate
sentinal node biopsy: neg
HER2/neu amplified 4.7
ER+/PR+
TOPO II neg
Oncotype dx 20
Bilat mastectomy with DIEP flap reconstruction
oophorectomy

2007:
6 cycles TCH (taxotere, carboplatin, herceptin)
finished 1 yr herceptin 05/07
Arimidex, stopped after almost 1 yr
Femara
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Old 07-23-2009, 01:23 PM   #9
tricia keegan
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Thanks Steph and delighted to hear the B9 results for you

I was'nt aware either that rads gave us a higher risk of skin cancer but did have a recent B9 result myself for a spot on my back.
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Tricia
Dx July '05 IDC 1.9cm Triple positive 3/9 nodes positive
A/C X 4 ..Taxol/Herceptin x 12 wks then herceptin 1 yr
Rads x 36 ..oophorectomy August '06
Currently taking Arimidex..
June 2011 osteopenia/ zometa x1 yearly- stopped Zometa 2015 as Dexa show normal bone density.
Stopped Arimidex July 2014- Restarted Arimidex 2015 for a further two years on the advice of my Onc.
2014 Normal Dexa scan
2018 Mammo all clear, still NED!
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Old 07-23-2009, 05:11 PM   #10
juanita
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glad you got good results!
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dxd 9-04, lumpectomy,
st 1, gr 3, er,pr-, her2 +,
2 tac,33 rads,6 cmf
1 yr herceptin,
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Old 07-24-2009, 12:37 AM   #11
harrie
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Steph, coincidentally I think I had the EXACT same thing on my back. It was biopsied and came back with same results. I had it on my back for over a month so i was getting concerned. The diameter was maybe 3/4 of an inch I'm guessing. I was so relieved since BRCA2 people have a higher incidence of melanoma. This happened over 6 months ago.
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*** MARYANNE *** aka HARRIECANARIE

1993: right side DCIS, lumpectomy, rads
1999: left side DCIS, lumpectomy, rads, tamoxifen

2006:
BRCA 2 positive
Stage I, invasive DCIS (6mm x 5mm)
Grade: intermediate
sentinal node biopsy: neg
HER2/neu amplified 4.7
ER+/PR+
TOPO II neg
Oncotype dx 20
Bilat mastectomy with DIEP flap reconstruction
oophorectomy

2007:
6 cycles TCH (taxotere, carboplatin, herceptin)
finished 1 yr herceptin 05/07
Arimidex, stopped after almost 1 yr
Femara
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