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Old 02-06-2019, 10:57 AM   #1
Nguyen
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Join Date: Nov 2005
Posts: 157
MacroGenics’ margetuximab beats Herceptin in phase 3

https://www.fiercebiotech.com/biotec...ceptin-phase-3
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Old 02-07-2019, 12:01 AM   #2
Pamelamary
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Location: Melbourne, Australia
Posts: 464
Re: MacroGenics’ margetuximab beats Herceptin in phase 3

Great news! A new 3rd line treatment?
Thanks, Nguyen.
__________________
Diagnosed 2004: Lumpectomy - 2 tumours, both grade 1 infiltrating duct carcinoma, about 12mm. ER+,
C-erbB-2 status 3+.
Clear margins, no nodal involvement.
Radiotherapy, i year Tamoxifen, 4 years Arimidex.
Rediagnosed 2012: Multiple bone metastases.
3/12: began on Marianne trial - T-DM1 + Pertuzamab/Placebo.
5/12:Unexpected development of numerous bilateral liver mets. Came off trial.
Started Docetaxol/ Herceptin + Zometa.
8/12:Bones stable +major regression in liver (!)
9/12:Can't take any more Docetaxol! Start on Herceptin and Tamoxifen. Cross fingers!
Changed to Denosumab.
11/12: Scan shows stable - yay!
11/13: Still stable :-) !!!
1/16: All stable, but lowered calcium, so switched to Zometa 3 monthly.
2/19: Happily still stable on Herceptin, Letrozole and 3 monthly Zometa.
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