!!! More interesting abstracts from Cancer conference - AACR
Hello again -
Maybe someone else has an easier way to view these abstracts, but I found the easiest way was to go to the AACR website and do the following:
To view the abstracts, go to http://www.abstractsonline.com/viewe...582CE7A0988%7D
and you can search by the number at the beginning of the study title. Just put the number in the search box and click “search.”
(The titles below will not connect to the abstract!) These are all by people I talked to and visited their poster. Wish I could impart how enthused they were about their findings and how they are carrying on from this point. At least you get the idea of how many directions the research is taking. You can search the AACR site by Session subjects as well.
VERY interesting study involving a hormone given to beef:
#2685 Zeranol (Z) increases aromatase mRNA expression in human normal breast pre-adipocytes (HNBPADs)
New drug from Genentech – an mTOR inhibitor, will begin phase 1 study:
#2707 Design and synthesis of dual PI3K/mTor inhibitors
A work with new antibody targets:
#1235 EPI0030, a humanized anti-VEGF rabbit monoclonal antibody, exhibits potent activity in preclinical models
Interesting investigation on bC brain metastases:
#4962 Breast cancer metastasis to the brain: effect of cyclophosphamide in a rat model
Novel targets and agents for imaging cancer:
#5014
89Zr-ranibizumab VEGF microPET imaging during sunitinib treatment visualizes changes with low tracer uptake in the center of the tumor and high uptake at the rim with a rebound tumor uptake after end of treatment.
Immune modulation and monitoring:
#5085 Maitake beta-glucan promotes neutrophil recovery from taxol induced chemotoxicity
__________________
"When I hear music, I fear no danger. I am invulnerable. I see no foe. I am related to the earliest times, and to the latest." H.D. Thoreau
Live in the moment.
MY STORY SO FAR ~~~~
Found suspicious lump 9/2000
Lumpectomy, then node dissection and port placement
Stage IIB, 8 pos nodes of 18, Grade 3, ER & PR -
Adriamycin 12 weekly, taxotere 4 rounds
36 rads - very little burning
3 mos after rads liver full of tumors, Stage IV Jan 2002, one spot on sternum
Weekly Taxol, Navelbine, Herceptin for 27 rounds to NED!
2003 & 2004 no active disease - 3 weekly Herceptin + Zometa
Jan 2005 two mets to brain - Gamma Knife on Jan 18
All clear until treated cerebellum spot showing activity on Jan 2006 brain MRI & brain PET
Brain surgery on Feb 9, 2006 - no cancer, 100% radiation necrosis - tumor was still dying
Continue as NED while on Herceptin & quarterly Zometa
Fall-2006 - off Zometa - watching one small brain spot (scar?)
2007 - spot/scar in brain stable - finished anticoagulation therapy for clot along my port-a-catheter - 3 angioplasties to unblock vena cava
2008 - Brain and body still NED! Port removed and scans in Dec.
Dec 2008 - stop Herceptin - Vaccine Trial at U of W begun in Oct. of 2011
STILL NED everywhere in Feb 2014 - on wing & prayer
7/14 - Started twice yearly Zometa for my bones
Jan. 2015 checkup still shows NED
2015 Neuropathy in feet - otherwise all OK - still NED.
Same news for 2016 and all of 2017.
Nov of 2017 - had small skin cancer removed from my face. Will have Zometa end of Jan. 2018.
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