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Old 10-12-2011, 06:45 PM   #1
CourtneyL
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Join Date: Aug 2008
Location: San Francisco
Posts: 260
The NEXT T-DM1 (MM-302)

I just had a meeting with Dr. Pamela Munster, UCSF's clinical trial director, yesterday and she told me about a very exciting new drug that is just starting to recruit:

http://clinicaltrials.gov/ct2/show/N...=mm+302&rank=1

The drug is similar to T-DM1 but is suppose to be better because the chemo molecule that it attaches is more effective. Instead of attaching DM1 to Herceptin, MM-302 attaches an anthracycline - a chemo proven to be more effective in breast cancer. This could really be something!

The only thing about the trial is you can't have had an anthracycline in the past, which many have. Fortunately I qualify for this trial if my next scan shows progression and my brain mets are stable. I can't seem to get access to T-DM1 so I may just give this new drug a try. Who knows? This could be our cure!

Always hoping,
__________________
4/17/08: Dx Stage IV at age 30 - extensive mets to liver, lungs, and bones. Er/Pr-, Her2+++
April 08-Aug 08:Taxotere, Cytoxan, Herceptin, Zometa - complete response!
Sept 08-Dec 08: Herceptin +Zometa for maintenance.

Jan 09-April 09: Brain mets. Add Tykerb. Watch and wait.
April 09: Gamma Knife 10 brain mets, add Xeloda.
Sept 09: Gamma Knife to 1 brain met.
Nov 09- April 10: Lung progression, add Gemzar to Herceptin, Zometa.
May 10- Sept 10: HER2 Vaccine Trial

Sept 10: Add Tykerb for more brain mets.
Oct 10: Gamma Knife to 7 brain mets.
Dec 10: Switch from Zometa to Denosumab.
Jan 11: Gamma Knife to 3 brain mets.
March 11: Gemzar/Herceptin for lung/bone progression.
April 11: More brain mets - Intrathecal Herceptin
June 11: Ixempra/Herceptin for lung, soft tissue progression.
Aug 11: Gamma Knife
Sep 11: Abraxane/Herceptin
Future: NED

Send me a PM if you'd like to follow my journey on Caringbridge.
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