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Old 01-05-2008, 10:08 PM   #1
AbbyDawg
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Question Carvedilol / Coreg - Headaches

Has anyone ever had nasty headaches from Carvedilol? These are dooozies. Started on it a month ago when LVEF dropped and was short of breath with increase of heart reat and BP. Have been on 12.5 mg twice a day and starting today am 25 mg twice a day. Had the headaches from the start within about 15-30 minutes of taking it and nothing (ibuprofen, acetaminephen, etc.) helps so far to get rid of them. Now with the double dose I am really getting clobbered. Any thoughts? Suggestions?

Am on Tykerb, Arimidex, Effexor, Synthroid, Celebrex, Carvedilol, Ambien, and Copaxone (MS injectible daily).

Stopped the Tykerb about 10 days while seeing a cardiologist and ENT to be sure OK to keep taking Tykerb. Am in TEACH study.

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Old 01-06-2008, 07:00 AM   #2
Sheila
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AbbyDawg
First off Carvedilol is a beta blocker, and if you are on 25 mg morning and night, you are on the highest dose....this is a medicine that you CANNOT just quit taking, basically you must be weaned off it or you can have some really nasty side effects to the heart. It lowers the blood pressure and heart rate, but if you are getting severe headaches, you need to let the Dr know at once....this is not common. Also, do not take this with any herbal or supplements unless checking with the Dr first...it can also interfere with other meds, alcohol etc.....Don't put up with the headaches, get to the Dr....something needs to be changed.
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Diagnosed at age 49.99999 2/21/2002 via Mammography (Calcifications)
Core Biopsy 2/22/02
L. Mastectomy 2/25/2002
Stage 1, 0.7cm IDC, Node Neg from 19 nodes Her2+++ ER PR Neg
6/2003 Reconstruction W/ Tissue Expander, Silicone Implant
9/2003 Stage IV with Mets to Supraclavicular nodes
9/2003 Began Herceptin every 3 weeks
3/2006 Xeloda 2500mg/Herceptin for recurrence to neck nodes
3/2007 Added back the Xeloda with Herceptin for continued mets to nodes
5/2007 Taken Off Xeloda, no longer working
6/14/07 Taxol/Herceptin/Avastin
3/26 - 5/28/08 Taxol Holiday Whopeeeeeeeee
5/29 2008 Back on Taxol w Herceptin q 2 weeks
4/2009 Progression on Taxol & Paralyzed L Vocal Cord from Nodes Pressing on Nerve
5/2009 Begin Rx with Navelbine/Herceptin
11/09 Progression on Navelbine
Fought for and started Tykerb/Herceptin...nodes are melting!!!!!
2/2010 Back to Avastin/Herceptin
5/2010 Switched to Metronomic Chemo with Herceptin...Cytoxan and Methotrexate
Pericardial Window Surgery to Drain Pericardial Effusion
7/2010 Back to walking a mile a day...YEAH!!!!
9/2010 Nodes are back with a vengence in neck
Qualified for TDM-1 EAP
10/6/10 Begin my miracle drug, TDM-1
Mixed response, shrinking internal nodes, progression skin mets after 3 treatments
12/6/10 Started Halaven (Eribulen) /Herceptin excellent results in 2 treatments
2/2011 I CELEBRATE my 9 YEAR MARK!!!!!!!!!!!!!
7/5/11 begin Gemzar /Herceptin for node progression
2/8/2012 Gemzar stopped, Continue Herceptin
2/20/2012 Begin Tomo Radiation to Neck Nodes
2/21/2012 I CELEBRATE 10 YEARS
5/12/2012 BeganTaxotere/ Herceptin is my next miracle for new node progression
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Old 01-07-2008, 12:33 PM   #3
janet11
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I'm on 12.5 twice a day too. No headaches though, and I've been on it for low LVEF for about 4 months.

How's your blood pressure? Irregardless, I'd report this to my cardiologist right way. Have you talked to him/his nurse about this?
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Dx July 2006 IDC 1.8cm, ER-/PR- HER2+ (FISH 7), KI67 High (60%) grade 3, TOPO II neg
Aug2006: lumpectomy, SNB (4 nodes neg), Stage 1
Jan 2007:
Finished 6 cycles of TCH (Taxotere, Carboplatin, Her ceptin). Then Herceptin every 3 weeks.
Feb 2007: Completed Radiation
May 2007: Stopped Herceptin due to low LVEF (49%)
July 2007: LVEF now 44% -- starting Coreg
May 2008: Heart NORMAL! Yippee.
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