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Old 02-12-2010, 10:37 AM   #1
Jean
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Join Date: Oct 2005
Location: New Jersey
Posts: 3,154
Trial information on herception prior to surgery

without chemo at MD Anderson.
Neoadjuvant Herceptin for Ductal Carcinoma In Situ of the Breast

The goal of this clinical research study is to find out if a single dose of the
drug Herceptin (trastuzumab) given before surgery can kill cancer cells or slow
the growth of cancer cells in women who have DCIS.
http://utm-ext01a.mdacc.tmc.edu/dept...ndex/2004-0701

jean

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__________________
Stage 1, Grade 1, 3/30/05
Lumpectomy 4/15/05 - 6MM IDC
Node Neg. (Sentinel node)
ER+ 90% / PR-, Her2+++ by FISH
Ki-67 40%
Arimidex 5/05
Radiation 32 trt, 5/30/05
Oncotype DX test 4/17/06, 31% high risk
TOPO 11 neg. 4/06
Stopped Arimidex 5/06
TCH 5/06, 6 treatments
Herceptin 5/06 - for 1 yr.
9/06 Completed chemo
Started Femara Sept. 2006
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Old 02-12-2010, 01:05 PM   #2
Hopeful
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Join Date: Aug 2006
Posts: 3,380
Re: Trail information on herception trt

"The goal of this clinical research study is to find out if a single dose of the
drug Herceptin (trastuzumab) given before surgery can kill cancer cells or slow the growth of cancer cells in women who have DCIS"


They are doing one Herceptin tx prior to surgery for DCIS. Seems like a very focused study.

Hopeful
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Old 02-12-2010, 04:22 PM   #3
Jean
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Join Date: Oct 2005
Location: New Jersey
Posts: 3,154
Re: Trial information on herception prior to surgery

Exciting isn't it? Maybe we can kill the monster in the very earliest of stages...I think that is where the direction is heading. Maybe our future will hold for women not to advance further, with having their yearly mammorgams catching the DCIS and stomping out the Her2..very interesting trial.

jean
__________________
Stage 1, Grade 1, 3/30/05
Lumpectomy 4/15/05 - 6MM IDC
Node Neg. (Sentinel node)
ER+ 90% / PR-, Her2+++ by FISH
Ki-67 40%
Arimidex 5/05
Radiation 32 trt, 5/30/05
Oncotype DX test 4/17/06, 31% high risk
TOPO 11 neg. 4/06
Stopped Arimidex 5/06
TCH 5/06, 6 treatments
Herceptin 5/06 - for 1 yr.
9/06 Completed chemo
Started Femara Sept. 2006
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Old 02-13-2010, 10:35 PM   #4
weety
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Join Date: Dec 2009
Posts: 56
Re: Trial information on herception prior to surgery

I had read about another trial (on clinicaltials.gov) on giving one dosage of herceptin before surgery for IDC with estrogen receptors negative, to see if the herceptin caused the receptors to become positive. All very interesting stuff!
__________________
Diagnosed 7/09 with 7mm IDC ER weakly +, PR -, Her2+

TCH chemo 8/09-12/09

Ooph/hysterectomy 4/10

Started Femara 6/10

Completed year of herceptin 10/11

Zometa 1/11 (2X/yr for 2yrs)

Hopefully nothing else!!!!
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