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09-30-2007, 03:21 PM
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#1
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Senior Member
Join Date: Mar 2006
Posts: 1,843
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10-01-2007, 06:49 AM
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#2
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Senior Member
Join Date: Aug 2007
Location: Silicon Valley, CA
Posts: 76
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Please explain
R.B. -
Please explain what the article on research re: Omega-3 supplementing anti-depression and anti-bipolar medication has to do with breast cancer and Herceptin...
Thanks,
Sandy in Silicon Valley
__________________
1992 - age 44/ ER-/PR+ Stage II dx - mastectomy, CAF x 6 cycles; Tamoxifen
1997 - BRCA1 mutation dx'd
1998 - ovaries removed
1999 - off Tamoxifen, on Arimidex
2003 - dx'd Stage IV - lymph nodes & lungs. ER-/PR-/HER2neu+++.
Tx: Herceptin & Taxotere (6 cycles).
2005 - 2.9cm x 3.6cm brain tumor. Craniotomy, CyberKnife. 9 mo. staph aureus infection at incision site - 2nd craniotomy. Two small brain mets CyberKnife'd.
2006 - revisit Xeloda - dosage lowered to 2500mg/day, 5 cycles.
2007 - "spot" dx'd on qtrly brain MRI - same location as CyberKnife 7/05. > by 2-4mm per quarter - - radiation injury or re-growing cancer? Tykerb added to Herceptin - July, still "watching & waiting". Otherwise, fully functional...
"The majority of people are not only afraid of holding a wrong opinion, they are afraid of holding an opinion alone." Kierkegaard
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10-02-2007, 07:09 AM
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#3
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Senior Member
Join Date: Mar 2006
Posts: 1,843
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Why the thumbs down?
A search on this site on depression produced 234 hits.
Depression links to anxiety neural function etc. Omega three plays a key role in neural function.
Neural function links into the fats pathways and endocrine functions.
Omega three reduces the risk of breast cancer.
RB
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10-02-2007, 07:54 AM
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#4
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Senior Member
Join Date: Aug 2007
Location: Silicon Valley, CA
Posts: 76
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Thumbs down - this is NOT bc-related research!
R.B. -
I think what you've surmised is an example of specious reasoning, and is NOT scientifically validated.
Just because a website gets hundreds of hits, does not make it relevant to people seeking bc info - like me.
YouTube sites with videos of funny dog tricks and two- legged dogs doing "normal" stuff get thousands of hits - and are probably, IMO, about as relevant to bc & her2neu+++ issues as the research you cited.
Sandy in Silicon Valley
__________________
1992 - age 44/ ER-/PR+ Stage II dx - mastectomy, CAF x 6 cycles; Tamoxifen
1997 - BRCA1 mutation dx'd
1998 - ovaries removed
1999 - off Tamoxifen, on Arimidex
2003 - dx'd Stage IV - lymph nodes & lungs. ER-/PR-/HER2neu+++.
Tx: Herceptin & Taxotere (6 cycles).
2005 - 2.9cm x 3.6cm brain tumor. Craniotomy, CyberKnife. 9 mo. staph aureus infection at incision site - 2nd craniotomy. Two small brain mets CyberKnife'd.
2006 - revisit Xeloda - dosage lowered to 2500mg/day, 5 cycles.
2007 - "spot" dx'd on qtrly brain MRI - same location as CyberKnife 7/05. > by 2-4mm per quarter - - radiation injury or re-growing cancer? Tykerb added to Herceptin - July, still "watching & waiting". Otherwise, fully functional...
"The majority of people are not only afraid of holding a wrong opinion, they are afraid of holding an opinion alone." Kierkegaard
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10-02-2007, 03:21 PM
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#5
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Senior Member
Join Date: Mar 2006
Posts: 1,843
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Hi Sandy,
As I said I fully understand your scepticism.
I am standing for my position even if it has not yet reached the main stream.
The search for depression was not just on any U-Tube site - it was on this site HER2 Support. So depression is a topic of concern on this site.
There has also been media reports that Tamoxifen may be an effective initial treatment in bipolar disorder - another intriguing fact.
I am not going to convince you that that there are links between the fats pathways, the immune system, neurological function etc.
I don't understand why if I am reading this correctly you are angry with me.
The body's systems are a great deal more interdependent and integrated than most realise. That is one of the things I have come to appreciate. I wish there was a simpler way to explain what I am trying to say.
Many thanks
RB
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10-02-2007, 05:18 PM
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#6
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Senior Member
Join Date: Sep 2005
Location: Central Coast, CA
Posts: 3,207
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interesting topic
Hey RB
I appreciate all the research you are able to find on these topics. Too true, the interrelationships are complex and not amenable to classic double-blind studies. However the volume of evidence is overwhelming and mounting - whether or not we (any of us, not just me!) can ever understand it completely. Both on the mind/body factors as they influence chemical changes and on the importance of FA composition. In the end, we are all just chemicals and energy - and science is still trying to catch up. Just wait until we start really looking at the "spirit" factor!
Thanks again for your energy on this.
__________________
Chris in Scotts Valley
June 2002 extensive hi grade DCIS (pre-cancer-stage 0, clean sentinal node) Mastectomy/implant - no chemo, rads. "cured?"
9/2004 Diag: Stage IV extensive liver mets (!) ER/PR- Her2+++
10/04-3/05 Weekly Taxol/Carboplatin/Herceptin , complete response!
04/05 - 4/07 Herception every 3 wks, Continue NED
04/07 - recurrence to liver - 2 spots, starting tykerb/avastin trial
06/07 8/07 10/07 Scans show stable, continue on Tykerb/Avastin
01/08 Progression in liver
02/08 Begin (TDM1) trial
08/08 NED! It's Working! Continue on TDM1
02/09 Continue NED
02/10 Continue NED. 5/10 9/10 Scans NED 10/10 Scans NED
12/10 Scans not clear....4/11 Scans suggest progression 6/11 progression confirmed in liver
07/11 - 11/11 Herceptin/Xeloda -not working:(
12/11 Begin MM302 Phase I trial - bust:(
03/12 3rd times the charm? AKT trial
5/12 Scan shows reduction! 7/12 More reduction!!!!
8/12 Whoops...progression...trying for Perjeta/Herceptin (plus some more nasty chemo!)
9/12 Start Perjeta/Herceptin, chemo on hold due to infection/wound in leg, added on cycle 2 &3
11/12 Poops! progression in liver, Stop Perjeta/Taxo/Herc
11/12 Navelbine/Herce[ptin - try for a 3 cycles, no go.
2/13 Gemzar/Carbo/Herceptin - no go.
3/13 TACE procedure
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