Skin met question
Hi everyone
I have a question about skin mets. I have one on and it has changed during my navelbine, herceptin and everolimus/placebo treatment. Initially there was an obvious change - it got less red, smaller and started to break into red dots. In the past week, there are more dots but in places where I had no inflammation before. I had last week off navelbine because of low neutrophils but still had herceptin. I have had a week off earlier when I had neutropenic fever.
I am wondering if the changes that I am seeing are just a normal part of the healing process or progression? I get so darned sick of seeing this thing everyday! I also have numerous lung mets and positive axilla node. Last CT showed 30% reduction in lung mets and 14% in node so I am concerned that this is a sign of progression. Next CT in 3 weeks.
Would love to here from others with skin mets.
Thanks
__________________
Amanda xx
40 year old Mum to three gorgeous kids - son 5 and daughters 8 and 11
Wife to my wonderfully supportive husband of 17 years!
22 February 2011 - Diagnosed Early Breast Cancer IDBC Stage2b (ER/PR -ve, Her2+ve +++) - 38 years old
(L) skin sparing mastectomy with tissue expander, axilla clearance (2/14 affected) clear margins.
Fec*3, Taxotere and herceptin*2 - stopped due to secondary diagnosis
June 24 2011 Stage IV - Skin met, axilla node, multiple lung lesions
Bolero3 trial - Navelbine, Hereptin weekly, daily Everolimus/Placebo
February 2012 - July 2012 Tykerb and Xeloda - skin mets resolved, Lungs initially dramatically reduced but growing again
August 2012 (turn 40!) tykerb and herceptin (denied compassionate use of TDM1) while holidaying in Italy!
September 2012 - January 2013 TDM1 as part of the Th3resa trial - lymph nodes resolved, lungs slowly progressing.
January 2013 - herceptin, carboplatin and Perjeta (compassionate access)
April 2013 - Some progression in lungs and lymph nodes - Abraxane, Herceptin and Perjeta
July 2013 - mixed response - dramatic reduction of most lung disease, progression of smaller lung nodules and cervical and hilar nodes - ? Add avastin.
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