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Old 01-27-2007, 10:49 AM   #1
fullofbeans
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Lightbulb

Thanks Hebla, I did not realise that DCA was used to treat acidosis, that is very interesting indeed and I can understand now why you have put these papers (DCA & cell pH) in the same post. I must definitly get more knowledgeable on this.. In the meantime it sounds like alkalising my diet is the way forward..Is it what you do, if I may ask?
__________________

35 y/o
June 06: BC stage I
Grade 3; ER/PR neg
Her-2+++; lumpectomies

Aug 06: Stage IV
liver mets: 6 tumours
July 06 to Jan 07: 2*FEC+6*Taxotere; 3*TACE; LITT
March 07- Sept 07: Vaccination trial (phase 2, peptide based) at the UW (Seattle).
Herceptin since 2006
NED til Oct 09
Recurrence Oct 2009: to internal mammary gland since October 2009 missed on Oct and March 2010 scan.. palpable nodes in May 2010 when I realised..
Nov 2011:7 mets to lungs progressing fast failed hercp/tykerb/xeloda combo..

superior vena cava blocked: stent but face remains puffy

April 2012: Teresa Trial, randomised to TDM1
Nov 2012 progressing on TDM1
Dec 2012 blockage of my airways by tumours, obliteration of these blocking tumours breathing better but hoping for more- at mo too many tumours to count in the lungs and nodes.

Dec 2012 Starting new trial S-222611 phase 1b dual egfr her2+ inhibitor.



'Under no circumstances should you lose hope..' Dalai Lama
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Old 01-27-2007, 03:36 PM   #2
R.B.
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Heblaj01 - another very thought provoking and informative post which I need time to assimilate. Thank you for your work.

Mitochondria have a key relationship with fats which are "burnt" to make energy. If you think of the mitochondria as the boiler room in a steam ship...

Complicated and highly simplistic but maybe if you put the wrong fuel in the burner the exhaust products are more damaging to the "environment" than the average, the "grate" clogs up, mitochonria stop working and the surrounding environement is damaged.

Fats and the mitochonria and the mitochondrial membanes is a fascinating enormous difficult to comprehend topic if you are wandering on the web.

RB
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Old 01-27-2007, 03:41 PM   #3
R.B.
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Karina

If you are looking at risk reduction factors you might like to look at the posts on omega three and six.

Some trials have come up with risk reduction factors as high as seventy percent.

You can search clicking on the search button above and entering search terms omega three, DHA, etc.

There is quite a lot in this link but there is some thought provoking material.

http://www.her2support.org/vbulletin...ght=greek+diet

RB
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Old 01-28-2007, 07:08 PM   #4
heblaj01
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Karina,
To answer your question on what specific & effective steps to fight acidity, I am not able to be very helpfull as I am not yet convinced anything available without prescription is going to be working.
What RB suggests as well as what you are implementing make sense to me.
What is making me still leery about supplementing with pills such as cesium or high dose potassium pushed by many commercial outfits is the lack of proof, the potential side effects & the debunking of supplers claims in sites such as quakwatch:
http://www.quackwatch.org/01Quackery...SH/coral2.html
Acid/Alkaline Theory of Disease Is Nonsense Gabe Mirkin, M.D.

This article by Dr G. Mirkin is not recent. So, in view of the two recent papers posted at the begining of this thread he might change some of his statements.
The full text of these papers are so technical that only those well versed in biology (not my case) can appreciate the validity of their findings & guess what patients might be able to do to help themselves.
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Old 01-29-2007, 12:10 PM   #5
fullofbeans
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Hi there,



Thank R.B yes I have been supplementing my diet with fish oil supplement; i also use probiotic (specially when was on chemo) daily.



Thanks Hebla for the link to quackwatch I had seen it before but I still think that there is something to eating mainly veg product and eating them lives. I know, when I did when I was first diagnosed until my 4th chemo (after which I thought my body was not absorbing anything much anyway). Anyway until after my 2nd chemo I felt and looked, much better.



Many CAM adept claim that this type of food can cure you.. Well off course I do not think that but somewhat there is a lot of sense to go back to a diet we were evolved to eat, meat was rare events. This has changed drastically in the last 50 years. It may just be a coincidence that the healthy stuff tend to leave an alkaline ash, but they did not explain in quackwatch why the variation in ash.



I am convinced that the increase in cancer is mainly/very importantfactor due to diet; how else could we explain that Japonese people have a low rate of BC but the Japonese people born in the west get it at the same rate: it cannot be genetic. Also why would it increase at such a rate.



Love

Karina
__________________

35 y/o
June 06: BC stage I
Grade 3; ER/PR neg
Her-2+++; lumpectomies

Aug 06: Stage IV
liver mets: 6 tumours
July 06 to Jan 07: 2*FEC+6*Taxotere; 3*TACE; LITT
March 07- Sept 07: Vaccination trial (phase 2, peptide based) at the UW (Seattle).
Herceptin since 2006
NED til Oct 09
Recurrence Oct 2009: to internal mammary gland since October 2009 missed on Oct and March 2010 scan.. palpable nodes in May 2010 when I realised..
Nov 2011:7 mets to lungs progressing fast failed hercp/tykerb/xeloda combo..

superior vena cava blocked: stent but face remains puffy

April 2012: Teresa Trial, randomised to TDM1
Nov 2012 progressing on TDM1
Dec 2012 blockage of my airways by tumours, obliteration of these blocking tumours breathing better but hoping for more- at mo too many tumours to count in the lungs and nodes.

Dec 2012 Starting new trial S-222611 phase 1b dual egfr her2+ inhibitor.



'Under no circumstances should you lose hope..' Dalai Lama
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Old 01-29-2007, 12:34 PM   #6
heblaj01
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Karina,
Your remark about the change in cancer incidence in Japanese who emigrate to north America as related to diet, not genetics, is quite right . Even if these emigrants keep their traditional diet they may still be unwillingly prone to cancer due to differences in the quality of some foods.
For instance I already mentioned in an other post a comment by Dr M.J. Folkman in a lecture where he briefly discussed the variations of incidence related to soybean based food consumption.
He said that soybean grown in north America lacks the genetic make up for genestein while soybean grown in Japan includes genestein which is considered as a cancer preventative food.
So epidemiology studies show that those emigrants consumming imported soybeans are better off than those eating the local grown variety.
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Old 02-06-2007, 03:40 AM   #7
fullofbeans
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Join Date: Jan 2007
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Posts: 617
Dear Hebla and R.B,

As you seem quite knowledgeable I was wondering if you could comment on the follwing statements:

"For two decades Dr. Perez Garcia has been using a treatment he calls Insulin Potentiation Therapy (IPT). It consists of giving a patient a dose of insulin followed by a tiny dose of chemotherapy.
Cancer cells have 15 times more insulin receptors than normal cells. The insulin dose helps to target chemotherapy into cancer cells because they have so many more insulin receptors. "

This could explain why keeping a low GI diet could be v.good in our case,

Still searching..

Best wishes
__________________

35 y/o
June 06: BC stage I
Grade 3; ER/PR neg
Her-2+++; lumpectomies

Aug 06: Stage IV
liver mets: 6 tumours
July 06 to Jan 07: 2*FEC+6*Taxotere; 3*TACE; LITT
March 07- Sept 07: Vaccination trial (phase 2, peptide based) at the UW (Seattle).
Herceptin since 2006
NED til Oct 09
Recurrence Oct 2009: to internal mammary gland since October 2009 missed on Oct and March 2010 scan.. palpable nodes in May 2010 when I realised..
Nov 2011:7 mets to lungs progressing fast failed hercp/tykerb/xeloda combo..

superior vena cava blocked: stent but face remains puffy

April 2012: Teresa Trial, randomised to TDM1
Nov 2012 progressing on TDM1
Dec 2012 blockage of my airways by tumours, obliteration of these blocking tumours breathing better but hoping for more- at mo too many tumours to count in the lungs and nodes.

Dec 2012 Starting new trial S-222611 phase 1b dual egfr her2+ inhibitor.



'Under no circumstances should you lose hope..' Dalai Lama
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Old 02-06-2007, 10:18 AM   #8
heblaj01
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Karina,
Being much less knowledgeable than you think (no background in life sciences) I have to rely on what experts are saying & on common sense deductions from the evidence.
The main arguments against IPT from the standpoint of a layman are:
1. it has been around for a long time &
2. there is still no verifiable response data
3. there has been no research papers in PubMed
4. there has been no clinical trial

If the treatment was very effective at least one of the above negative points should have been answered positively.
Now, for a more scientific discussion of IPT here is the viewpoint of conventional medicine:
http://www.quackwatch.org/01Quackery...ancer/ipt.html
Why You Should Stay Away from Insulin Potentiation Therapy (IPT)
Robert Baratz, M.D., D.D.S., Ph.D.

P.S.
A quick search of PubMed gave me only one answer which seems to remotely relate to IPT:
http://www.ncbi.nlm.nih.gov/entrez/q...=pubmed_docsum
RNAi-mediated silencing of insulin receptor substrate 1 (IRS-1) enhances tamoxifen-induced cell death in MCF-7 breast cancer cells.
I don't fully understand this abstract, but if I read it correctly it, would seem to be somewhat the opposite of IPT.

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