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Old 01-01-2007, 06:06 PM   #1
heblaj01
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Join Date: Apr 2006
Posts: 543
Newly found mutation of HER-2/neu(also called ERBB2) in liver cancer & role of Tykerb

In this preclinical study the newly found mutation in 11% of liver cancer cells may explain resistance to currently available treatments. In the discussion section Tykerb (Lapatinib) is mentioned as possibly effective against liver cancer.
http://www.biomedcentral.com/1471-2407/6/278
A novel mutation in the tyrosine kinase domain of ERBB2 in hepatocellular carcinoma
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