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Old 01-25-2010, 03:28 PM   #1
sally
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How long on Adriamycin?
I have been on Adriamycin since Sept 09. I get it 3 weeks on one week off. My PET last week showed that all my spots have faded but my onc is keeping me on since it worked so well. Just wondering how long everyone else was on it. Thanks for any info. Sally
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Dx March 2004 HER2+ er/pr+ 8/16 + lymphnodes mets to the liver Stage IV / 6 cycles of TCH and 33 rads . NED Continued Herceptin 3 years w/ Femara. Tumor markers start to rise in Jan of 2007 and swiched to Tamoxifen. August of 2007 found more mets to liver and lymphnodes outside of liver. Went on Tykerb/Xeleoda--spots on liver gone found large mass between intestines. March 2008 started TCH. Stopped Carboplatin due to allergy. Still on Taxotere and Herceptin. Nov 2008 mass is gone. 3 new spot on liver and one on spine. Radiation on spine. tykerb/gemzar for liver mets. PET in April 09 showed shrinkage still a little activity, continue tykerb/gemzar until Aug 09. PET showed new spot on my spine more on my liver and a bunch of enlarged lymphnodes in upper chest. Start Adriamycin Sep 09. more radiation on spine . April 2010- Still on Adriamycin 3wks on 1 wk off and zometa every 28 days. PET -May 2010 showed progression. Starting Herceptin/Navelbine on June '10
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Old 01-25-2010, 06:04 PM   #2
whatz
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Re: How long on Adriamycin?
I had Adriamycin together with Cytoxan for 4 treatments (every 3 weeks) but I'm also stage I so that probably does not compare real well.
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4/09 suspicious lump in left breast
5/09 biopsi lead to diagnosis ER/PR -
Her2+.Grade 3,full masectomy left breast,sentinel nodes clear,Stage 1
6/09 Adriamycin + Cytoxan 4 treatments (every 3 weeks) followed by Taxol + Herceptin, 1 treatment weekly for 12 weeks, followed by Herceptin for 40 weeks
MRI Brain 4/10 clear
CT Body 4/10 clear
PET Body 2/11 clear
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Old 01-26-2010, 07:03 AM   #3
Yorkiegirl
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Re: How long on Adriamycin?
I was under the impression that Adriamycin had a life time amount that could be taken as it is very toxic to the heart. I can't remember the amount. Sorry I wasn't any help.
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Vicki
Texas
Biopsy Dx'd 3-23-05 Age 48
MRM 4-5-05 w/ 2 tumor's 5cm, and 6 cm (right side)
IDC (poorly differentiated infiltrating ductual carcinoma)
5+/16 nodes
Stage III A
Grade 3
ER/PR-, Her2/neu ++
Ki67 78%
Begin Chemo 5-2-05 4XAC Dose Dense , 4X Abraxane Dose Dense (ended August 05)
28 Rad's ended October 13 2005
Started Herceptin Weekly August 2005 for one year
Had a Simple mastectomy left side after Mamo showed incresed micro-calcifications. Jan. 17 2006.
Brain MRI Feb.2006--All Clear
August 28, 2006 Last Weekly Herceptin.
October 2006--Colonoscopy, 6 Polyp's removed--all B9
PET Scan July 2007
Abdominal MRI Oct. 2007---2 Right Kidney Cysts
Core Biopsy-- Lump on Scar Line 1-10-08---B9
Brain MRI 6-2008--All Clear
PET/CT Scan 6-2008
Sept. 8 2008, 4CM area removed from mastectomy scar line. Proved to be B9.
PET/CT Scan-- July 2009 --All clear
August 17,2009 ---Had Port Removed
6 Years NED -- April 5,2011
DX'd with Melanoma left arm 10-10-2011
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Old 01-27-2010, 09:31 AM   #4
Mary Jo
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Re: How long on Adriamycin?
I was on adriamycin with Cytoxan also. Received it 4 times every other week.

Mary Jo
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Dx. 6/24/05 age 45 Right Breast IDC
ER/PR. Neg., - Her2+++
RB Mast. - 7/28/05 - 4 cm. tumor
Margins clear - 1 microscopic cell 1 sent. node
No Vasucular Invasion
4 DD A/C - 4 DD Taxol & Herceptin
1 full year of Herceptin received every 3 weeks
28 rads
prophylactic Mast. 3/2/06

17 Years NED

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Old 01-27-2010, 03:37 PM   #5
mirtillo
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Re: How long on Adriamycin?
I received Adriamycin together with Taxol 4 times, every 3 weeks.
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Laura
Left breast IDC, 4/4/07 Quadrantectomy & Axillary dissection: 4/11 pos. nodes.
G3, Er-Pr+, Her2+++.
4 Adriamicin & Taxol + 4 CMF + 35 rads + 1 year Herceptin + Femara for 5 years
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Old 01-28-2010, 02:19 PM   #6
MJo
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Re: How long on Adriamycin?
I know that adriamycin is an old and very powerful chemo. I would make sure that your oncologist is monitoring you closely while you are on this drug. It has been shown to cause heart valve damage in a small percentage of patients. I also have read that there is a lifetime amount you can take. I'm sure you'll be just fine as long as you are monitored. Make sure to ask questions if you have them.
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IDC, Stage I, Grade 2
Oncotype DX Score 32
Her2++ E+P+, Node Neg.
Lumpectomy 11/04/05 Clear Margins
3 Dose dense AC (Couldn't tolerate 4)
4 Dose dense Taxol & Herc. (Tolerated well)
36 weeks Herceptin (Could not complete one year due to decrease in MUGA score)
2 years of Arimidex, then three years of Femara
Finished Femara May 2011
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Old 01-28-2010, 06:42 PM   #7
Carolyns
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Re: How long on Adriamycin?
Hi Sally,

I am not sure about that drug as I too had it in combination with other drugs. Doxil is a drug like Adriamycin that many doctors are using to treat Stage IV breast cancer for long periods of time.

Please check back in and let us know your findings.

Thanks, Carolyn
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Old 01-29-2010, 10:52 AM   #8
AlaskaAngel
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Re: How long on Adriamycin?
http://www.virtualcancercentre.com/d...sp?drugid=1723

Per this site, recommended cumulative lifetime dose is 550mg/m2.

(As a stage I, I was prescribed doxorubicin every 3 weeks for 6 treatments, but because I declined the use of blood stimulators my counts took longer to recover between treatments and I actually received it every 4 weeks for 6 treatments.)

A.A.
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