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Aromatase Inhibitors/Weakly ER +
Hi all,
I would like to hear from those of you who are taking AI's and are weakly ER+ . I understand this is not common and most folks are strongly ER and PR+.
Nevertheless my onc has me on Arimidex. In Canada we are not given % but only rated ER+1,+2 or +3. I am a +1 and I don't know how that translates into percentages.
Problem is....there is no real clear proof that AI's will help me and I don't want to ruin my bones for nothing. Sure, I can take Fosamex or something but one drug usually leads to taking another one and I would like to avoid that!
Any studies done on weakly ER+ and AI's? Any studies showing relatively long term effects, say 10-15 years after AI's and weakly er+?
Mucho thanks
Diannes
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Three years and 5 months NED
Dx: Aug 2008 right breast IDC with 50% of tumor DCIS, Stage II or IIA, tumor size: 2.1 cm
Grade 3
8/9 Richardson/Bloom test
ER+ weakly positive
Alred Score: 4 (suggesting I would strongly benefit from hormone therapy)
PR-,
HER2 positive +++
No vascular invasion
No lymph nodes involved
Surgery: Sept. 9, 2008 -Modified radical mastectomy, right breast. I chose to have a simple mastectomy on the left. Began Taxotere/Carboplatin/Herceptin November, 2008. Finished T/C March 2009. Finished #16 Herceptin Sept. 09. AI's and Tamoxifen made me sick. Began natural Tamoxifen which is Quercetin, I3C and a combo of other supplements. I am also a DES Daughter. There is now a link between DES exposure in utero and breast cancer!
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