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12-24-2011, 09:32 AM
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#21
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Senior Member
Join Date: Jan 2008
Location: Evergreen, Colorado
Posts: 454
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Re: Update on the Journey for NED
Sheila,
As always, so nice to see a post from you. Sorry to hear of continued challenges. UGH!!! Many of us know the frustration well.
It sounds as if your home is warm and cheery this holiday season. Sitting in front of the colorful lights is one of life's simple pleasures for sure. I hope you feel up to soaking up their magical glow.
I agree with the wise input from everyone on the board. More drugs in the pipeline!! More vaccines on the way. Then of course, there are our old friends that seem to help us out. I am on my 3rd run with a taxane and 2nd go around with my old friend Abraxane. Maybe another run with an old friend will tide you over until "Mr. P" becomes available.
Sending warm holiday wishes and I look forward to your inspiring posts in 2012.
Lori
__________________
2007
Oct - Diagnosed - Stage IV 5 c.m. IDC - Left Side er/pr- Her2+++ Node + 2/14 - Single Liver Met Double Mastectomy Nov - Begin T+H 2008
Feb-Complete 6 cycles- T&H- NED
March - Continue - Herceptin Only
April - Rads for 6 weeks
2009
Continue Herceptin - Continue NED
April - Recurrance- 3 cm. Liver Met
May - Cryosurgery
June - November - Abraxane + Herceptin
Aug - PET/CT - CTC = 0 Back to NED
2010
January - Continue NED
July - Recurrance - 3 cm Liver Met CTC=1
August - Cryosurgery #2
August - November Navelbine
November - Back to NED - End Navelbine
2011
Feb - Recur - 4 cm Liver Met - Same Left Lobe
March Surgery it is -Couldn't get a clean margin
July - Confirmed continued liver involvement
August - Begin Herceptin + Tykerb
October - Mixed results from H+T
Add Abraxane + H + T - Nov - April
2012
January PET Scan - It's working!!
April - Back to NED
July - Recurrance
August - Begin TDM-1 Trial (Taxol + TDM-1)
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12-27-2011, 11:27 AM
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#22
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Senior Member
Join Date: Nov 2010
Location: Doylestown, ohio
Posts: 334
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Re: Update on the Journey for NED
Sheila, I first want to say that you look amazing. Something must be working. I hope that you can find some comfort from that neck pain. I saw an interesting break thru recently for gyno cancer ( a chemo wash that olny takes an hour and you are done). Lets hope this advancement will get to breat cancer as well. Stay strong and I am praying for you. Darlene
__________________
DX Sept 30 2010 at the age of 49. Oh crap! 1.5 cm idc, stage 1 grade 3 er/pr+, her2+ no lymph nodes, mastectomy Oct/10. Started 6 rounds of TCH Dec/10 and will continue herceptin until Nov /11 and just started femara.
Stray kitten found my lump while I was playing with it. It is now my pet and my dog is not real happy about that.
Mammo good
last herceptin 11/21/11 YAY
reconstruction 12/09/11
Chapter closed 12/10/11, hopefully, fingers crossed
Bone scan, chest xray, clear
04/27/12 Expander removed, implant put in, ahh sigh of relief, much more comfortable
Sept 30, 2014, 4 years NED
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12-27-2011, 01:06 PM
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#23
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Senior Member
Join Date: Feb 2008
Location: Georgia
Posts: 1,486
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Re: Update on the Journey for NED
Thinking of you, Shelia. You are one of my heroes.
Amelia
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12-27-2011, 06:00 PM
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#24
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Senior Member
Join Date: Mar 2009
Posts: 508
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Re: Update on the Journey for NED
Hi Sheila. I haven't been on for a while, but hoped to see an update from you today. I'm so sorry you are having pain, but will be praying for a new plan that does great things for you. We all need to keep asking for the cure! Sending love and hugs and wishes for a kind 2012!
Barb A.
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12-29-2011, 01:03 PM
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#25
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Senior Member
Join Date: Aug 2006
Location: Sheboygan, WI
Posts: 2,582
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Re: Update on the Journey for NED
Hi Sheila...Although we have never met, I do consider you a long time friend. I care about you and what you are going through.
You are always a pillar of strength and encouragement to all. Today I post to offer some encouragement to you....not to mention a GENTLE HUG AND LOTS OF LOVE FROM MY HEART.
I am sorry you are having pain issues and that treatment hasn't been working for you. No, asking for a CURE is definitely not asking too much and I PRAY PRAY PRAY that one would be found and so many wouldn't have to struggle and suffer through this very nasty disease.
Merry Christmas dear friend and may 2012 bring you health......a deep seeded peace and more joy than that beautiful heart of yours can hold.
You are loved "sister!"
Mary Jo
__________________
"Be still and know that I am God." Psalm 46:10
Dx. 6/24/05 age 45 Right Breast IDC ER/PR. Neg., - Her2+++ RB Mast. - 7/28/05 - 4 cm. tumor Margins clear - 1 microscopic cell 1 sent. node No Vasucular Invasion 4 DD A/C - 4 DD Taxol & Herceptin 1 full year of Herceptin received every 3 weeks 28 rads prophylactic Mast. 3/2/06
17 Years NED
<>< Romans 8:28
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12-30-2011, 01:18 PM
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#26
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Senior Member
Join Date: May 2009
Posts: 510
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Re: Update on the Journey for NED
Hi Sheila,
Sorry to hear about your latest struggles with this beast. May 2012 bring you the magical drug or combo that will destroy this beast. Hope you're enjoying your holiday season without so much pain and discomfort. And hope that rather than the world ending in 2012, what will end is HER-2+ breast cancer and other cancers as well!!
Love,
Marcia
__________________
ER+ (30%)/PR-/HER-2+, stage 3
Diagnosed on 02/18/09 at 38 with a huge 12x10 cm tumor, after a 6 month delay. Told I was too young and had no risk factors. Found swollen node during breastfeeding.
March-August 09: neo-adjuvant chemo, part of a trial at Stanford (4 DD A/C, 4 Taxotere with daily Tykerb), loading dose of Herceptin
08/12/09 - bye bye boobies (bilateral mastectomy)
08/24/09 - path report shows 100 % success in breast tissue (no cancer there, yay!), 98 % success in lymphatic invasion, and even though 11/13 nodes were still positive, > 95 % of the tumor in them was killed. Hoping for the best!
September-October 09: rads with daily Xeloda
02/25/10 - Cholecystectomy
05/27/10 - Bone scan clear
06/14/10 - CT scan clear, ovarian cyst found
07/27/10 - Done with Herceptin!
02/15/11 - MVA-BN HER-2 vaccine trial
03/15/11 - First CA 15-3: 12.7 and normal, yay!
10/01/11 - Bone scan and CT scan clear, fatty liver found
now on Tamoxifen and Aspirin
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12-31-2011, 12:26 AM
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#27
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Senior Member
Join Date: Dec 2011
Posts: 585
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Re: Update on the Journey for NED
Im new to the board here, but I have read your posts and you are truly inspirational. Im so sorry to hear of your current symptoms, but will certainly pray that you are relieved of them soon.
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12-31-2011, 01:43 AM
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#28
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Senior Member
Join Date: Feb 2007
Location: Paris, France
Posts: 858
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Re: Update on the Journey for NED
Sheila I hope you are able to enjoy the Holidays. Just to tell you that at midnight, when I think of the ones I love, I will include you in my wishes for the New Year hoping that 2012 will bring you the best. I just can't stand that you are not well. You are our precious sister. Love and Hugs. Michka
__________________
08.2006 3 cm IDC Stage 2-3, HER2 3+ ER+90% PR 20%
FEC, Taxol+ Herceptin, Mastectomy, Radiation, Herceptin 1 year followed by Tykerb 1 year,Aromasin /Faslodex
12.2010 Mets to liver,Herceptin+Tykerb
03.2011 Liver resection ER+70% PR-
04.2011 Herceptin+Navelbine+750mg Tykerb
06.2011 Liver ned, Met to sternum. Added Zometa 09.2011 Cyberknife for sternum
11.2011 Pet clear. Stop Navelbine, continuing on Hercpetin+Tykerb+Aromasin
02.2012 Mets to lungs, nodes, liver
04.2012 TDM1, Ned in 07.2012
04.2015 Stop TDM1/Kadcyla, still Ned, liver problems
04.2016 Liver mets. Back on Kadcyla
08.2016 Kadcyla stopped working. mets to liver lungs bones
09.2016 Biopsy to liver. no more HER2, still ER+
09.2016 CMF Afinitor/Aromasin/ Xgeva.Met to eye muscle Cyberknife
01.2017 Gemzar/Carboplatin/ Ibrance/Faslodex then Taxotere
02.2017 30 micro mets to brain breathing getting worse and worse
04.2017 Liquid biopsy/CTC indicates HER2 again. Start Herceptin with Halaven
06.2017 all tumors shrunk 60% . more micro mets to brain (1mm mets) no symptoms
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01-03-2012, 05:34 PM
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#29
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Senior Member
Join Date: Feb 2008
Location: Bayarea,CA
Posts: 679
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Re: Update on the Journey for NED
Sheila,
You are such a brave fighter and have been an inspiration for so many of us here. Praying hard that you get right combination to get better soon! Sending best wishes for 2012! You are always in my thoughts.
hugs,
shobha
__________________
DX: 06-30-2007 - left breast -stage IIIB, Her2/Neu 3+++, ER weakly positive, PR-
Taxol+herceptin weekly for 3 months
FEC+herceptin every 3 weeks for 3 months
BRCA 1 and 2 - Negative
Jan 2008 - Bilateral mastectomy, prophylactic Rt. side.
Radiation for 5 weeks
Completed my yr of herceptin on 07-14-2008
Brain MRI - 3/2/09 Clean
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01-03-2012, 05:44 PM
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#30
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Senior Member
Join Date: Aug 2010
Location: New York, New York
Posts: 1,580
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Re: Update on the Journey for NED
Sheila,
I was just going to post what Joan said. I am on the trial, one of 63 in the U.S. that combines T-DM1 with Pertuzumab. In 6-8 months, it should be approved, from what I'm hearing.
Happy New Year, you continue to be an inspiration to us all.
Karen
__________________
World Trade Center Survivor (56th Floor/North Tower): 14 years and still just like yesterday.
Graves Disease, became Euthyroid via Radioactive Iodine, June 2001.
Thyroid Eye Disease. 2003. Decompression surgery in 2009; eyelid lowering surgery in 2010.
Diagnosed: June 2010, liver mets. ER-/PR+10%; HER2+++.
July 2010: Begin Taxol/Herceptin. Eliminate sugar from diet. No surgery or radiation.
January 2011: NED
April 2011: Progression in liver only. Other previous affected areas eradicated. Stop Taxol/Herceptin after 32 infusions.
May 2011: Brain MRI: clear.
May 2011: Begin Tykerb daily, Xeloda twice per day for one week on, one week off, and Herceptin.
November 2011: Progression in liver. All other tumors remain eradicated.
December 2011: BEGIN TRIAL #09-093 Taxol, MCC-DM1 (T-DM1), Perjeta.
Trial requires scans every six weeks, bloodwork and infusions weekly.
Brain MRI: clear.
January 2012: NED. Liver mets, good riddance!
March 2012: NED. Developed SMA (rare blood clot) in intestinal artery and loss of sight in right eye due to optical nerve neuropathy. Resolved when Taxol removed this month.
Continue Protocol of T-DM1 weekly and Perjeta every 3 weeks.
May 2012: NED.
June 2012: Brain MRI: clear.
June-December 2012: NED.
December 2012: TRIAL CONCLUDED; ENTER TRIAL EXTENSION #09-037. CT, Brain MRI, bone scan: clear. NED.
January-March 2013: NED.
June 2013: Brain MRI: clear. CEA upticking; CT shows new met on liver.
July 3, 2013: DISASTER STRIKES during liver ablation: sloppy surgeon cuts intercostal artery and I bleed out, lose 3.5 liters of blood, have major hemothorax, and collapsed lung requiring emergency resuscitative thoracotomy, lung surgery, rib rearrangement and cutting deep connective tissue, transfusion. Ablation incomplete. This life-saving procedure would end up causing me unforgiving pain with every movement I make, permanently, otherwise known as forever.
July 26, 2013: Try Navelbine/Herceptin. Body too weak after surgery and transfusion. Fever. CEA: Normal.
August 16, 2016: second dose Navelbine/Herceptin; CEA: Normal. Will skip doses. Watching and waiting.
September 2013: NED, Herceptin only. CEA: Normal. Started Arimidex.
October-November 2013: NED. Herceptin and Arimidex. CEA, CA125, 15-3: Normal.
December 2013: Something brewing. PET lights up on little spot on liver; CEA upward trend, just outside normal. PET and triphasic liver scan confirm Little Met. Restart Perjeta with Herceptin, stay on Arimidex. Genomic sequencing completed for future treatments, if necessary.
January 2014: Ablate Little Met on the 6th. Happy New Year.
March 2014: Brain MRI: clear. PET/CT reveal liver mets return; new lung mets. This is not funny.
March 2014: BEGIN TRIAL #10-005 A(11)-Temsirolimus plus Neratinib.
April 2014: Genomic testing indicated they could work, they did not. Very strange drug combo for me, felt weird.
April 2014: Started Navelbine and Herceptin. Needed something tried and true, but had significant progression.
June 2014: Doxil and Herceptin.
July 2014: Progression. Got nothing out of it. Brain: NED.
July 2014: Add integrative medical hematologist-oncologist to my team. Begin supplements. These are tumor-busting, immune system boosters. Add glutathione, lysine and taurine IV infusions every three weeks.
July 2014: Begin Gemzar, Herceptin & Perjeta. Happy.
August 2014: ECHO perfect.
January 2015: Begin weekly Vitamin D Analog infusions. 25 mcg. via port.
February 2015: CT: stable.
April 2015: Gem working, but not 100%. Looking into immunotherapy. Finally, treatments for the 21st century!
April 2015: Penn Medicine. Dendritic cell immunotherapy.
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01-03-2012, 08:42 PM
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#31
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Senior Member
Join Date: Jan 2009
Location: Colorado Springs, CO
Posts: 430
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Re: Update on the Journey for NED
Oh Sheila,
I'm so sorry to hear this news. As Brenda would say . . . crap on a crapstick!! I think you know that you are my hero, and if anyone is deserving of a cure, it is you! I hope that your doctors are able to come up with a good option that will not only clear up your pain, but will zap those #%*^)&%!%@# cancer cells.
Please keep us posted as to how you are doing. Sending you warm hugs and keeping you in my thoughts and prayers.
Love, Alice
__________________
9/15/08 (age 52) - Mammo: calcifications
9/22/08 - Biopsy: DCIS, grade 3. ER,PR status: Pos. in 75-90% of tumor cells.
10/01/08 - Ob/Gyn appt.: found complex, mostly cystic mass on right ovary - 11cmx12cmx 8cm
10/15/08 - Hysterectomy & Oophorectomy, Lumpectomy: Cyst on uterus, not ovary - all was benign. Breast - 5 of 6 bad margins. 2 Sentinel Lymph nodes removed, both negative. Stage 0, Tis, N0
12/11/08 - Mastectomy & DIEP reconstruction: Surprise! 2 cm Invasive DC, grade 2 found. One benign internal mammary lymph node. Stage 1, T1c, N0, all clean margins. ER+ (Proportion Score = 2/5, Intensity Score = 2/3) and PR+(Proportion Score = 3/5, Intensity Score = 2/3)
HER2 score = 3+
1/09/09 - Oncotype DX: Recurrence S/core of 60 !?!?! ER status is NEG!! PR staus is NEG! HER2 score = 12.2 (still positive, greater than 11.5 is positive).
1/20/09 - Started chemo: TCH
5/26/09 - FINISHED CHEMO!
1/05/10 - FINISHED HERCEPTIN!
1/22/10 - Port-a-catheter removed!
3/07/18 - Still NED
9/10/23 - Still NED
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01-04-2012, 06:12 AM
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#32
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Senior Member
Join Date: Sep 2005
Location: Stockton, NJ
Posts: 4,179
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Re: Update on the Journey for NED
Dear Sheila
I am sorry things aren't working right now. Consider returning to something that did in the past such as Taxol (or Taxotere) with Herceptin and Tykerb - will they do that combo or any combo with Herceptin and Tykerb together. Just thinking out loud on what can stabilize you until you can get TDM1 or a trial with something else.
You are one of the strongest women I have ever met and a true warrior. My thoughts and prayers are with you.
__________________
Kind regards
Becky
Found lump via BSE
Diagnosed 8/04 at age 45
1.9cm tumor, ER+PR-, Her2 3+(rt side)
2 micromets to sentinel node
Stage 2A
left 3mm DCIS - low grade ER+PR+Her2 neg
lumpectomies 9/7/04
4DD AC followed by 4 DD taxol
Used Leukine instead of Neulasta
35 rads on right side only
4/05 started Tamoxifen
Started Herceptin 4 months after last Taxol due to
trial results and 2005 ASCO meeting & recommendations
Oophorectomy 8/05
Started Arimidex 9/05
Finished Herceptin (16 months) 9/06
Arimidex Only
Prolia every 6 months for osteopenia
NED 18 years!
Said Christopher Robin to Pooh: "You must remember this: You're braver than you believe and stronger than you seem and smarter than you think"
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01-04-2012, 06:17 AM
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#33
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Senior Member
Join Date: Jan 2007
Location: Thornhill, Ontario
Canada
Posts: 2,320
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Re: Update on the Journey for NED
Dear Sheila,
Please keep your spirits up, I'm hoping your docs will find the right magic combo for you. You are one of the bravest, upbeat, women I "know."
Also hoping 2012 is the year of the cure!!
all the best
caya
__________________
ER90%+/PR 50%+/HER 2+
1.7 cm and 1.0 cm.
Stage 1, grade 2, Node Negative (16 nodes tested)
MRM Dec.18/06
3 x FEC, 3 x Taxotere
Herceptin - every 3 weeks for a year, finished May 8/08
Tamoxifen - 2 1/2 years
Femara - Jan. 1, 2010 - July 18, 2012
BRCA1/BRCA2 Negative
Dignosed 10/16/06, age 48 , premenopausal
Mild lymphedema diagnosed June 2009 - breast surgeon and lymph. therapist think it's completely reversible - hope so.
Reclast infusion January 2012
Oopherectomy October 2013
15 Years NED!!
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01-04-2012, 07:25 AM
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#34
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Senior Member
Join Date: Aug 2003
Location: Morris, IL
Posts: 3,507
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Re: Update on the Journey for NED
As always, thank you all for the love and support...I truly do not know what I would do without all of you! Had scans last week, and will know the results next Wednesday...and know if a treatment change is in order...still having the pain but I think I am getting used to it...scary, another new normal.
In the mean time, one of my labs, Sophie, tore her ACL and will be having surgery Friday....hope the New year improves for all of us!
__________________
"Be kinder than necessary, for everyone you meet is fighting some kind of battle."
Hugs & Blessings
Sheila
Diagnosed at age 49.99999 2/21/2002 via Mammography (Calcifications)
Core Biopsy 2/22/02
L. Mastectomy 2/25/2002
Stage 1, 0.7cm IDC, Node Neg from 19 nodes Her2+++ ER PR Neg
6/2003 Reconstruction W/ Tissue Expander, Silicone Implant
9/2003 Stage IV with Mets to Supraclavicular nodes
9/2003 Began Herceptin every 3 weeks
3/2006 Xeloda 2500mg/Herceptin for recurrence to neck nodes
3/2007 Added back the Xeloda with Herceptin for continued mets to nodes
5/2007 Taken Off Xeloda, no longer working
6/14/07 Taxol/Herceptin/Avastin
3/26 - 5/28/08 Taxol Holiday Whopeeeeeeeee
5/29 2008 Back on Taxol w Herceptin q 2 weeks
4/2009 Progression on Taxol & Paralyzed L Vocal Cord from Nodes Pressing on Nerve
5/2009 Begin Rx with Navelbine/Herceptin
11/09 Progression on Navelbine
Fought for and started Tykerb/Herceptin...nodes are melting!!!!!
2/2010 Back to Avastin/Herceptin
5/2010 Switched to Metronomic Chemo with Herceptin...Cytoxan and Methotrexate
Pericardial Window Surgery to Drain Pericardial Effusion
7/2010 Back to walking a mile a day...YEAH!!!!
9/2010 Nodes are back with a vengence in neck
Qualified for TDM-1 EAP
10/6/10 Begin my miracle drug, TDM-1
Mixed response, shrinking internal nodes, progression skin mets after 3 treatments
12/6/10 Started Halaven (Eribulen) /Herceptin excellent results in 2 treatments
2/2011 I CELEBRATE my 9 YEAR MARK!!!!!!!!!!!!!
7/5/11 begin Gemzar /Herceptin for node progression
2/8/2012 Gemzar stopped, Continue Herceptin
2/20/2012 Begin Tomo Radiation to Neck Nodes
2/21/2012 I CELEBRATE 10 YEARS
5/12/2012 BeganTaxotere/ Herceptin is my next miracle for new node progression
6/28/12 Stopped Taxotere due to pregression, Started Perjeta/Herceptin
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01-04-2012, 07:35 AM
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#35
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Senior Member
Join Date: Jun 2011
Location: Iowa
Posts: 231
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Re: Update on the Journey for NED
Sheila,
A cure is not too much to ask for, and we are all praying that your oncologist will find "the one" for you. Pertuzumab is coming this year- 2012, so says my oncologist! Just have to hang on til then! I think of you and all your encouragement, keep the faith. Remember, faith is believing in things when common sense tells you not to.
Huggs,
Kristin
__________________
[B]Kristin
Aug 2010: diagnosed stage 3b, 4 mo. after birth of son. 29 yrs old and breastfeeding, ER/PR-, Her-2+ started Neoadjuvant therapy: 4x FEC, 10x abraxane & Herceptin
Feb 2011: L mx with recon. Path. showed only DCIS but 4/10+ nodes.
March 2011: 6 wks rads.
Mother passed, lower back pain.
Late May 2011: Bone mets but organs clear; Tykerb, Xeloda, Xgeva. Stopped Herceptin. Implant infected: removed implant.
October 2011: Bone progression; Gemzar and Carboplatin & restarted Herceptin.
Jan 2012: Progression, re-classified as ER+; Tykerb, Herceptin, Zoladex & Femara. Anti-E is working!
May 2012: ovaries out, markers stable but elevated. Cont. Herceptin, Tykerb, Xgeva & Femara.
Dec 2012: aromasin
Jan 2013: faslodex, herceptin, tykerb
Jun: Kadcyla
Aug: Rads to hip, then Perjeta, Herceptin & Taxotere
Nov 2013: Perjeta, Herceptin, Halaven
Early 2014: Affinitor, Aromasin, Perjeta, Herceptin.
June 2014: Estradiol, Perjeta, Herceptin
Aug 14: Tamoxofin, H & P
http://kristin-notdying-blog.blogspot.com/
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01-04-2012, 09:13 AM
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#36
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Senior Member
Join Date: Oct 2006
Location: Southern California
Posts: 900
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Re: Update on the Journey for NED
Shelia,
You are never far from my mind. I hope the results of your scans are a nice surprise for you rather than the need for a new combo. May 2012 be YOUR year!
__________________
Gerri
Dx: 11/23/05, Lumpectomy 12/12/05
Tumor 2.2 cm, Stage II, Grade 3, Sentinel Node biopsy negative
ER+ (30%) /PR+ (50%), HER2+++
AC X 4 dose dense, Taxol X 4 dose dense
Herceptin started with 2nd Taxol, given weekly until chemo done
then given every 3 weeks for one year ending on March 16, 2007
Radiation 30 treatments
Tamoxifen - 2 yrs (pre-menopausal)
May 2008 - Feb 2012 Femara
Aug 2008 - Feb 2012 Zometa every 6 months
March 2012 - Stop Femara, now Evista for bone strengthening
********** Enjoy the little things, for one day you may look back and realize they were the big things. - Robert Brault
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01-15-2012, 01:32 PM
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#37
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Senior Member
Join Date: Sep 2005
Location: Newton, MA
Posts: 951
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Re: Update on the Journey for NED
Hi Shelia,
I am sorry that you have had this setback. Pain should not be the new normal. My thoughts are always with you, and I so appreciate the help that you gave me when I was having issues with my insurance approving my Tykerb/Herceptin combination.
You should continue to hope to become NED. As you are aware, new therapies are being developed. You just need to be find one that works for your stubborn variety of Her2. You are a tenacious person, and I know you will continue to search for the treatment that eventually works.
Thank you for keeping us updated. You remain very special to me.
Kind regards,
Barbara H.
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01-15-2012, 07:16 PM
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#38
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Senior Member
Join Date: Sep 2005
Location: Central Coast, CA
Posts: 3,207
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Re: Update on the Journey for NED
Kristin
I love it when people. Quote my favorite movies!
__________________
Chris in Scotts Valley
June 2002 extensive hi grade DCIS (pre-cancer-stage 0, clean sentinal node) Mastectomy/implant - no chemo, rads. "cured?"
9/2004 Diag: Stage IV extensive liver mets (!) ER/PR- Her2+++
10/04-3/05 Weekly Taxol/Carboplatin/Herceptin , complete response!
04/05 - 4/07 Herception every 3 wks, Continue NED
04/07 - recurrence to liver - 2 spots, starting tykerb/avastin trial
06/07 8/07 10/07 Scans show stable, continue on Tykerb/Avastin
01/08 Progression in liver
02/08 Begin (TDM1) trial
08/08 NED! It's Working! Continue on TDM1
02/09 Continue NED
02/10 Continue NED. 5/10 9/10 Scans NED 10/10 Scans NED
12/10 Scans not clear....4/11 Scans suggest progression 6/11 progression confirmed in liver
07/11 - 11/11 Herceptin/Xeloda -not working:(
12/11 Begin MM302 Phase I trial - bust:(
03/12 3rd times the charm? AKT trial
5/12 Scan shows reduction! 7/12 More reduction!!!!
8/12 Whoops...progression...trying for Perjeta/Herceptin (plus some more nasty chemo!)
9/12 Start Perjeta/Herceptin, chemo on hold due to infection/wound in leg, added on cycle 2 &3
11/12 Poops! progression in liver, Stop Perjeta/Taxo/Herc
11/12 Navelbine/Herce[ptin - try for a 3 cycles, no go.
2/13 Gemzar/Carbo/Herceptin - no go.
3/13 TACE procedure
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01-15-2012, 08:48 PM
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#39
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Senior Member
Join Date: May 2006
Posts: 3,142
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Re: Update on the Journey for NED
I have my fingers crossed for a decent scan report on Wednesday. I think re-trying something that worked pretty well is a good idea unti Mr. P. gets approval from the FDA to come and help everyone who needs his assistance.
Take good care of yourself.
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01-17-2012, 12:09 AM
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#40
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Senior Member
Join Date: Apr 2011
Location: Michigan
Posts: 1,173
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Re: Update on the Journey for NED
Shelia, you are always in my prayers as is your family. Gods blessings to all of you.
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