 |
|
07-13-2008, 02:13 PM
|
#21
|
|
Senior Member
Join Date: Sep 2005
Location: Central Coast, CA
Posts: 3,207
|
karen,all my love and prayers to you. you are one strong lady and an inspiration to us all. glad you have some help. let others take care of you, and let rick do his job - to love you!much lovechris
__________________
Chris in Scotts Valley
June 2002 extensive hi grade DCIS (pre-cancer-stage 0, clean sentinal node) Mastectomy/implant - no chemo, rads. "cured?"
9/2004 Diag: Stage IV extensive liver mets (!) ER/PR- Her2+++
10/04-3/05 Weekly Taxol/Carboplatin/Herceptin , complete response!
04/05 - 4/07 Herception every 3 wks, Continue NED
04/07 - recurrence to liver - 2 spots, starting tykerb/avastin trial
06/07 8/07 10/07 Scans show stable, continue on Tykerb/Avastin
01/08 Progression in liver
02/08 Begin (TDM1) trial
08/08 NED! It's Working! Continue on TDM1
02/09 Continue NED
02/10 Continue NED. 5/10 9/10 Scans NED 10/10 Scans NED
12/10 Scans not clear....4/11 Scans suggest progression 6/11 progression confirmed in liver
07/11 - 11/11 Herceptin/Xeloda -not working:(
12/11 Begin MM302 Phase I trial - bust:(
03/12 3rd times the charm? AKT trial
5/12 Scan shows reduction! 7/12 More reduction!!!!
8/12 Whoops...progression...trying for Perjeta/Herceptin (plus some more nasty chemo!)
9/12 Start Perjeta/Herceptin, chemo on hold due to infection/wound in leg, added on cycle 2 &3
11/12 Poops! progression in liver, Stop Perjeta/Taxo/Herc
11/12 Navelbine/Herce[ptin - try for a 3 cycles, no go.
2/13 Gemzar/Carbo/Herceptin - no go.
3/13 TACE procedure
|
|
|
|
07-13-2008, 03:20 PM
|
#22
|
|
Senior Member
Join Date: Sep 2005
Location: Newton, MA
Posts: 951
|
Thinking of You!
Hi Karen,
Please know that I am sending positive thoughts your way. Try to take one day at a time and enjoy the fact that your husband is taking time off to be with you. Make sure that you have your needs met. Write them down and have your husband advocate for you. Although I can understand that you are worried right now about the road ahead, there just may be a treatment for you out there that will work for you. Ask what treatments or trials may be available. I wish all the best for you.
Barbara H.
|
|
|
|
|
07-13-2008, 04:07 PM
|
#23
|
|
Senior Member
Join Date: Jun 2007
Location: moved to Lancaster, Pa in June, 2010
Posts: 576
|
Karen, Sending tons of love, hugs, and prayers your way. Best of luck.
__________________
Debbie in North Carolina
Diag 10/2006-high grade invasive ductal carcinoma- mastectomy L breast
2.5 cm tumor ER/PR pos-Her2+++
4 rounds A/C, 4 rounds Taxol
Herceptin every 3 weeks until Jan. 2008
6/18/07 prophylatic mastectomy R breast
8/2007 started aromasin/stopped arimidex (side effects)
12/07 stopped aromasin due to side effects (now what?)
Finished herceptin 1/8/08
started tamoxifen for 2 years then will switch to femera
allergic to tamoxifen started femera 4/2008
June 20, 2008 portacath removed
Learnig to live life to the fullest!
Stopped Femera due to side effects
July 28, 2008 start trial for breast cancer vaccine
|
|
|
|
|
07-13-2008, 05:45 PM
|
#24
|
|
Senior Member
Join Date: Oct 2007
Posts: 1,851
|
Karen,
I'm so terribly sorry that you are having a tough time.
You have a lot going on. I'm sending prayers and healing vibes your way.
Best, Joan
__________________
Diagnosed stage 2b in July 2003 (2.3 cm, HER2+, ER-/PR-, 7+ nodes). Treated with mastectomy (with immediate DIEP flap reconstruction), AC + T/Herceptin (off label). Cancer advanced to lung in Jan. 2007 (1 cm nodule). Started Herceptin every 3 weeks. Lung wedge resection April 2007. Cancer recurred in lung April 2008. RFA of lung in August 2008. 2nd annual brain MRI in Oct. 2008 discovered 2.6 cm cystic tumor in left frontal lobe. Craniotomy Oct. 2008 (ER-/PR-/HER2-) followed by targeted radiation (IMRT). Coughing up blood Feb. 2009. Thoractomy July 2009 to cut out fungal ball of common soil fungus (aspergillus) that grew in the RFA cavity (most likely inhaled while gardening). No cancer, only fungus. Removal of tiny melanoma from upper left arm, plus sentinel lymph node biopsy in Feb. 2016. Guardant Health liquid biopsy in Feb. 2016 showed mutations in 4 subtypes of TP53. Repeat of Guardant Health biopsy in Jana. 2021 showed 3 TP53 mutations, BRCA1 mutation and CHEK2 mutation. Invitae genetic testing showed negative for all of these. Living with MBC since 2007. Stopped Herceptin Hylecta (injection) treatment in March 2020. Recent 2021 annual CT of chest, abdomen and pelvis and annual brain MRI showed NED. Praying for NED forever!!
|
|
|
|
|
07-13-2008, 08:38 PM
|
#25
|
|
Senior Member
Join Date: Oct 2006
Location: I live in Christmas, MI - located on the shores of Lake Superior.
Posts: 606
|
Just wanted to say that I hope the gamma knife works wonders and that you will soon be feeling better. I'm sorry to hear you have to deal with all this...and happy to hear your husband is being supportive. Hang in there!
__________________
Barb
10/03 Radical Mastectomy 3 cm tumor - 1/17 Nodes Stage II B, Her 2 +++ ER-/PR- 11/03 4 AC 4 Taxol 12/05 Stage IV - Lung met , Bone mets - Carbo, Taxotere, Herceptin 9/06 - 2 cm brain tumor 10/06 - Tumor removal surgery - Herceptin Halted 12/06 gamma knife tumor base.1/07 Navelbine/Herceptin 4/07 Rads to R femur 5/07 Stereotactic - new 2 cm brain tumor 4/07 Start Xeloda 5/07 Tykerb added 7/07 Brain MRI clean 10/07 .055 cm brain met found. 12/07 Stereotactic -1 cm brain tumor Start Tykerb 11/07 Abraxane/Herceptin 5/08 Cisplatin, Gemcitabine/Herceptin 6/08 Stereotactic to 1cm 9/08 Stereotactic repeat (growth). 11/08 Pet Scan Good but new tiny met on L lung/dead Brain surgery (no cancer cells found/scar tissue) 1/09 Chemo restarted 2/09 Pet Scan Bad - R larger very active/active L active lymph nodes both sides of chest MRI- mets slight increase 2/09 Start Doxil/Tykerb Treatment
|
|
|
|
|
07-14-2008, 08:13 AM
|
#26
|
|
Senior Member
Join Date: Jun 2007
Location: Bergenfield, NJ
Posts: 121
|
Dear Karen,
Sending you lots of love and prayers. We'll get through this together.
My love to you,
Gemma
__________________
My love to you all
Gemma
____________________________________
Dx July03 at 35
Rt,breast lump.,1 node+
ER+(98%)ER-, grade3
A/C 4rounds,Rad for 38 days
Tamoxifen 2004-05
Recurrence Feb.2006, radi double mastectomy canceled bec. of mets, StageIV lungs mets
Her2+++, BRCA negative
Taxol/Herceptin six rounds of Taxol from April06.then Herceptin alone til May07. Started Tykerb/Xeloda in Jun07-Sept.07 bec of progression of the lympnodes. Navalbine/Herceptin Sept.07 to April 08 due to progression . Gemzar/Hercptin Apr08.June08 Brain MRI showed Brain Mets.CraniectomyAug.1,08, tumor removed completely
completed 20 wbrt!
Started Doxil 10/31/08 (monthly) and weekly Herceptin
Ixempra on 2/13/09
due to multiple hepatic mets
will have Herceptin as well.
Radical rt.breast Mastectomy June2009.
Ixempra/Herceptin 11/06/09--increasing right axillary lymphanenopathy and enlarging left upper lobe nodule :-(
Taxotere/Herceptin 3/5/10,more liver mets, lungs, lymphnodes. 2 weeks on, one week off...
|
|
|
|
|
07-14-2008, 10:43 AM
|
#27
|
|
Senior Member
Join Date: Mar 2007
Location: CHARLOTTE NC USA
Home town (ECUADOR) South America
Posts: 542
|
you are in my though and prayers ..I ask to Divine Mercy for help everyminute for you ..my sweet sister !!and for all of us ...you are in my mind all the times ...you know it , you felt and you are reading now again ...I love you !!
__________________
Lily Diag April/06 5 months after give birth my son Max stage IV mets on liver (5 tumors) 38 year old, her2+++ and ER+PR+ from32 nodes 4 positives mastectomy right breast chemo before surgery herceptin/carboplatin/taxotere ,clear and surgery have radiation 20, `& then herceptin and tamoxifen NED until Aug/07 body only then 'n June 04-06-07 .1 lesion of 1.6 cm on cerebellum ...novalis ,open sugery 5m.m brain met again novalis, 4mm.In the liver. Waiting 2 months now 3 tumors enroll on T-MCC trial start first infusion Nov 5/07 at Dec 17 scan show one tumor despair the 2nd and 3th diminish Doc said great results until March/08 ct scan show progression 03-05-08 start tykerb & xeloda
|
|
|
|
|
07-14-2008, 01:43 PM
|
#28
|
|
Senior Member
Join Date: Apr 2006
Location: Wilmington, Del.
Posts: 1,126
|
I am glad you have hospice helping you. I also trust you will be one of the patients who cancels hospice when they are doing better. I hope the gamma knife fries the new tumor and that the chemo combination knocks back your other mets. Rhode Island is beautiful -- my wicked TV pleasure is Ghost Hunters, those Roto Rooter plumbers from Rhode Island. Take good care of yourself. A good husband is a blessing. MJO
__________________
MJO
IDC, Stage I, Grade 2
Oncotype DX Score 32
Her2++ E+P+, Node Neg.
Lumpectomy 11/04/05 Clear Margins
3 Dose dense AC (Couldn't tolerate 4)
4 Dose dense Taxol & Herc. (Tolerated well)
36 weeks Herceptin (Could not complete one year due to decrease in MUGA score)
2 years of Arimidex, then three years of Femara
Finished Femara May 2011
|
|
|
|
|
07-14-2008, 05:26 PM
|
#29
|
|
Senior Member
Join Date: Oct 2007
Posts: 57
|
What else can happen
Karen,
Sorry you are going through such difficult times now. I hope the support you are getting will allow you to rest and gain your strength. Regarding the brain lesion, I have had radiosurgery (similar to what you are getting) for a primary brain lesion and found the treatment helpful and painless. I am sending you healing prayers. Lida
|
|
|
|
|
07-15-2008, 02:59 PM
|
#30
|
|
Senior Member
Join Date: Jun 2006
Location: San Antonio, TX
Posts: 2,357
|
Sending love and hugs and prayers to you today! God bless, ma
__________________
MA in TX.
Grateful for each and every day....
Diag. 12/05 at age 60
Stage II, Grade 3, 4.5 cm primary tumor
ER/PR- Her2 +3 strongly positive
Her2 by FISH 7.7 amplified
vascular invasion
Ki67 20% borderline
Jan - March '06 Taxotere/Adriamycin X 3 to try to shrink tumor - it grew
April '06 Rt Modified Radical Mas, 7 of 9 nodes positive
April - Aug. '06 Herceptin/Taxol/Carboplatin X 8 (dose dense)
Sept - Dec. '06 Navelbine/Herceptin x 8 (dose dense)
Radiation & Herceptin Jan. 22 - March 1, 2007
Finished Herceptin Dec. 10 '08! One extra year.
Port removed August, 2012.
8 1/2 years since diagnosis! 5 1/2 Years NED!
|
|
|
|
|
07-16-2008, 10:41 AM
|
#31
|
|
Senior Member
Join Date: Jul 2006
Location: Memphis, Tennessee
Posts: 35
|
Hi Karen,
I'm so sorry you are caught in a whirlwind. I pray for peace and strength to slay this giant.
Love, Kathy
__________________
Kathy H
Diagnosed July 05 age 39
right side - stage 3c grade 3 occult BC, her2++, er/pr -
left side - likely stage 1 her2 -, er/pr+
4 A/C
Nov 05 - complete clinical remission
4 Taxotere/Herceptin
Surgery Feb 06 - pathologic complete remission
9 months of Herceptin
36 rad on right
Tamoxifen - 5yrs
NED!
|
|
|
|
|
07-30-2008, 04:22 PM
|
#32
|
|
Senior Member
Join Date: Sep 2006
Location: East Central Illinois
Posts: 89
|
HAS ANYONE ANY NEWS ON KAREN?
I am hoping someone has an update on how Karen is doing. She continues to be in my thoughts and prayers. Dear Karen, we miss you and love you.
Becca
|
|
|
|
|
07-30-2008, 07:24 PM
|
#33
|
|
Senior Member
Join Date: Nov 2005
Location: Northern Calif.
Posts: 981
|
Dear Karen,
I have been away from the boards recovering from surgery. I want to send you prayers and hugs as you brave this battle. So happy that your husband is able to take time off so you can regain strength and beat this nasty cancer back.
Hugs and Prayers,
Lexi
|
|
|
|
|
07-31-2008, 01:50 PM
|
#34
|
|
Senior Member
Join Date: Jun 2006
Location: San Antonio, TX
Posts: 2,357
|
Karen! We'd surely like to hear from you or your family! I left a message but know that you may be elsewhere fighting to get into that DM1 trial! Keep fighting gorgeous! ma
__________________
MA in TX.
Grateful for each and every day....
Diag. 12/05 at age 60
Stage II, Grade 3, 4.5 cm primary tumor
ER/PR- Her2 +3 strongly positive
Her2 by FISH 7.7 amplified
vascular invasion
Ki67 20% borderline
Jan - March '06 Taxotere/Adriamycin X 3 to try to shrink tumor - it grew
April '06 Rt Modified Radical Mas, 7 of 9 nodes positive
April - Aug. '06 Herceptin/Taxol/Carboplatin X 8 (dose dense)
Sept - Dec. '06 Navelbine/Herceptin x 8 (dose dense)
Radiation & Herceptin Jan. 22 - March 1, 2007
Finished Herceptin Dec. 10 '08! One extra year.
Port removed August, 2012.
8 1/2 years since diagnosis! 5 1/2 Years NED!
|
|
|
|
|
08-02-2008, 11:55 PM
|
#35
|
|
Senior Member
Join Date: Mar 2007
Location: Hilo, Hawaii
Posts: 1,867
|
Karen,
Still have you in my thoughts. Take care.
Hugs,
Maryanne
__________________
*** MARYANNE *** aka HARRIECANARIE
1993: right side DCIS, lumpectomy, rads
1999: left side DCIS, lumpectomy, rads, tamoxifen
2006:
BRCA 2 positive
Stage I, invasive DCIS (6mm x 5mm)
Grade: intermediate
sentinal node biopsy: neg
HER2/neu amplified 4.7
ER+/PR+
TOPO II neg
Oncotype dx 20
Bilat mastectomy with DIEP flap reconstruction
oophorectomy
2007:
6 cycles TCH (taxotere, carboplatin, herceptin)
finished 1 yr herceptin 05/07
Arimidex, stopped after almost 1 yr
Femara
|
|
|
|
Posting Rules
|
You may not post new threads
You may not post replies
You may not post attachments
You may not edit your posts
HTML code is Off
|
|
|
All times are GMT -7. The time now is 03:39 PM.
|
Linear Mode
