Dear ladies,
There is a trend to concurrent herceptin + hormonal dosing, in fact I just finished reading an article a couple weeks ago stating that if you are ER+ and on herceptin, you should be also taking at least an A.I. Tamoxifen (TAM) + herceptin, there are 3 distinct camps on that one; one says OK and the another 2 say no! Still question if the TAM doesn't cause (1) tumor proliferation or (2)cross-talk between the E and EGF receptors creating TAM resistance.
There is also a thought that if you are HER2 and ER ++, there is a hierarcha relationship between them and tumor growth, where HER2 has by far the greater influence on the tumor.
Regards,
Al
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