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04-09-2009, 09:01 AM
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#1
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Senior Member
Join Date: Aug 2007
Location: Newport Beach, CA
Posts: 161
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Had first Zometa infusion this week
I wanted to get back to you, Gerri and Barbara, as I had my first Zometa infusion on Tuesday. As you said, it only took a short time, about 30 minutes, and they hydrated me along with it.
There were no side effects right away and I felt energetic the whole day. But, as I watched "American Idol" in the evening, I began to feel an achy twinge here and there and in the middle of the night I felt muscle aches and flu-like symptoms and I had chills and was miserable.
So, yesterday I stayed in bed and just took things slowly. Today I am much better and back at it again. After reading what Jean wrote about the benefits of bisphosphonates and reduction in recurrence rates, I'm really glad I decided to do this.
Hopefully, my second one in six months will be better and at least I'll know what to expect and manage it accordingly with Tylenol.
Your words of wisdom really helped! Thanks again.
Vicki
__________________
Diagnosed 12/03 at age 53
1.5cm tumor, ER-PR-, Her2 3+(rt side)
Stage 1B, Three negative nodes from Sentinel Node Biopsy
Paget's of the nipple, Infiltrating Ductal Carcinoma and DCIS of the rt breast
Bloom-Richardson score 8/9, P53+ 60-70%, Ki-67+ 30-40%
Skin-sparing mastectomy with immediate lat-flap reconstruction and saline implants, 1/04
Chemo: FAC, five sessions every three weeks Feb.-May 04, then switched to HTC weekly for 12 weeks, June-Aug 04
Zometa every 6 months for osteopenia, started April 09
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04-09-2009, 11:36 AM
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#2
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Senior Member
Join Date: May 2008
Location: Oregon
Posts: 110
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Vic,
I'm so glad your side effects were not too bad.My onc says the first dose is the hardest and the SE's get better with each dose. I hope so since I'm going back for my second round next week.
Henny
__________________
Henny
Dx 3/07 IDC and DCIS Her2+ ER- PR-
Stage IIb 1/15 nodes
A/C, Taxol, Herceptin
Bilateral mastectomies with recon
Zometa 2/yr for 3 yrs- finished 8/2011
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04-09-2009, 02:13 PM
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#3
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Senior Member
Join Date: Sep 2005
Location: Stockton, NJ
Posts: 4,179
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Hi Vicki Girl!
I was the same way with my first Zometa but it never happened that way again. I even got a 101 fever. Second dose was non-eventful and I have been getting them every 6 months since Nov 2005. I go for my next one May 22.
You'll probably be fine next time.
Big hugs to you
__________________
Kind regards
Becky
Found lump via BSE
Diagnosed 8/04 at age 45
1.9cm tumor, ER+PR-, Her2 3+(rt side)
2 micromets to sentinel node
Stage 2A
left 3mm DCIS - low grade ER+PR+Her2 neg
lumpectomies 9/7/04
4DD AC followed by 4 DD taxol
Used Leukine instead of Neulasta
35 rads on right side only
4/05 started Tamoxifen
Started Herceptin 4 months after last Taxol due to
trial results and 2005 ASCO meeting & recommendations
Oophorectomy 8/05
Started Arimidex 9/05
Finished Herceptin (16 months) 9/06
Arimidex Only
Prolia every 6 months for osteopenia
NED 18 years!
Said Christopher Robin to Pooh: "You must remember this: You're braver than you believe and stronger than you seem and smarter than you think"
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04-09-2009, 07:40 PM
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#4
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Senior Member
Join Date: Oct 2006
Location: Southern California
Posts: 900
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Hi Vickie,
So glad to hear that things went relatively well with your first infusion. The aches and flu-like symptoms are pretty common from what I understand. Like you, I am so glad that I'm getting Zometa considering the extra benefits the recent research has shown. Did your insurance end up paying for it?
So glad you checked in to let us know how everything went.
Take care,
__________________
Gerri
Dx: 11/23/05, Lumpectomy 12/12/05
Tumor 2.2 cm, Stage II, Grade 3, Sentinel Node biopsy negative
ER+ (30%) /PR+ (50%), HER2+++
AC X 4 dose dense, Taxol X 4 dose dense
Herceptin started with 2nd Taxol, given weekly until chemo done
then given every 3 weeks for one year ending on March 16, 2007
Radiation 30 treatments
Tamoxifen - 2 yrs (pre-menopausal)
May 2008 - Feb 2012 Femara
Aug 2008 - Feb 2012 Zometa every 6 months
March 2012 - Stop Femara, now Evista for bone strengthening
********** Enjoy the little things, for one day you may look back and realize they were the big things. - Robert Brault
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04-09-2009, 07:41 PM
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#5
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Senior Member
Join Date: Sep 2005
Posts: 52
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zometa infusion
Can you fill me in on the benefits of zometa please? I'm not very compliant with my fosamax and every morning as I run in the dark I promise I'll do better. My onc briefly mentioned it as a replacement but didn't seem gung ho about it.
Should I switch?
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04-09-2009, 07:58 PM
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#6
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Senior Member
Join Date: Oct 2006
Location: Southern California
Posts: 900
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dberg,
I took a quick look and found this link. Also, try to search for research by Dr. Gnat and Zoledronic Acid (Zometa), that is where you will find the most info. Hope this helps.
http://www.cancer.gov/clinicaltrials...ronic-acid0608
__________________
Gerri
Dx: 11/23/05, Lumpectomy 12/12/05
Tumor 2.2 cm, Stage II, Grade 3, Sentinel Node biopsy negative
ER+ (30%) /PR+ (50%), HER2+++
AC X 4 dose dense, Taxol X 4 dose dense
Herceptin started with 2nd Taxol, given weekly until chemo done
then given every 3 weeks for one year ending on March 16, 2007
Radiation 30 treatments
Tamoxifen - 2 yrs (pre-menopausal)
May 2008 - Feb 2012 Femara
Aug 2008 - Feb 2012 Zometa every 6 months
March 2012 - Stop Femara, now Evista for bone strengthening
********** Enjoy the little things, for one day you may look back and realize they were the big things. - Robert Brault
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04-14-2009, 10:33 PM
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#7
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Senior Member
Join Date: Jun 2007
Location: RHODE ISLAND
(Ed getting me a latte on 2nd Cancerversary Cruise 2008)
'BELIEVE': To accept as true or real, To have faith in, To presume
ALWAYS BELIEVE
Posts: 2,999
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Vic, wondering how you are doing and wanting you to know I was thinking of you over the weekend. Wishing you well.>>Believe51
__________________
9/7/06Husband 50yrs=StageIV IBC/HER2+,BoneMets10/06TaxotereX10,'H'1X wk,Zometa,Tamoxifen4/12/07Last Tax5/18/07Pet=Rapid Cell Activity,No Organ Mets,Lytic Lesions,Degeneration,Some Bone Repair5/07ChemoFail6/01/07Pleural Thoracentisis=Effusions,NoMalignantCells6/19/07+7/2/07DFCI
6/25/07BrainMRI=BrainMets,Many<9mm7/10/07WBR/PelvisRad37.5Gx15&Nutritionist8/19/07T/X9/20/07BrainMRI=2<2mm10/6/07Pet=BoneProgression
10/24/07ChemoFail11/9/07A/Cx10,EndTam12/7/07Faslodex12/10/07Muga7512/13/07BlasticLesions1/7/08BrainMRI=Clear4/1/08Pet=BoneImprovement,
NoProgression,Stable4/7/08BrainPerfect5/16/08Last A/C8/26/08BrainMets=10(<9mm)9/10/08Gamma10/30/08Met=5mm12/19/08Gamma5mets5
12/22/08SpinalMets1/14/09SpinalRads2/17/09BrainMRI=NoNewMets4/20/09BoneScan5/14/09Ixempra6/1/09BrainMRI=NumerousMets6/24/09DFCIw/DrBurstein6/26/09Continue
Ixempra/Faslodex/Zometa~TM now lower7/17/09Stop Ixempra By Choice9/21/09HOSPICE10/16/09Earned His Deserved Wings And Halo=37 Month Fight w/Stage 4 IBC, Her2+++,My Hero!!
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