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Tykerb + different chemo than Xeloda?
I'm looking for anyone who has used any other chemos (other than Xeloda) in conjunction with Tykerb. I'm told I'm running out of treatment options since I had some regression and some progression with the Tykerb and Xeloda combo in my liver. My doc is concerned that there aren't many studies that include Tykerb with something other than Xeloda. After the last scans, he started me on Tykerb and Herceptin. I'm just trying to see if anyone out there has done any combos with Tykerb so I can share the info with him. He's also got his research department looking for any trials I could get into, particularly TDM-1. I'm in Louisville, KY if anyone has any suggestions! Thanks, all!
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Krissi
12/27/10 - IDC, rt breast (approx. 15 cm), lymph nodes, age 36. 1/7/11 - stage 4 IDC, extensive liver mets, Bone mets (spine, sacrum, rib, sternum, upper arm), ER-/PR-, HER2+++; 1/12/11 - port, 1/17/11- startweekly Taxol/Herceptin, monthly Zometa
3/8/11- decrease in all tumors, bones healing. 3/11- 3 wks on/1 off Taxol/Herceptin, +Zometa
6/6/11 - decrease in all tumors, healing bones, 2-4 new liver lesions. 3 wks on/1 wk off Taxol/Carbo/Herceptin, +Zometa
7/29/11 - liver progression, others stable; 8/11-drop taxol/carbo, start Navelbine
12/11 - liver progression; begin AC, drop Herceptin;
1/12 - liver enzymes normal, 2/6 results show regression in liver, stable others, but 9 tiny brain mets (largest 7 mm). Begin 13 WBRs 2/6; 2/29-start Tykerb, 3/7, start Xeloda
5/2012- liver progression and regression, liver biopsy confirms HER2+++. drop Xeloda, start Herceptin, Tykerb, Zometa.
5/2012- brain MRI shows all lesions gone except 1, 2mm shrinking!
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