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06-06-2007, 03:15 PM
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#21
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Senior Member
Join Date: Nov 2005
Location: Northern Calif.
Posts: 981
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Andi,
Please know that I am thinking of you. Such a difficult decision to be made. I am hopeful that there will be a tx for you. I also believe in miraculous healings. I pray every day for just that to be for all of us.
Love,
Lexi
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06-06-2007, 03:58 PM
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#22
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Senior Member
Join Date: Sep 2005
Location: Central Coast, CA
Posts: 3,207
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Andi,
Not the update I was hoping for. I cannot imaging how difficult this is for your family, and will continue to hold you all in my prayers. thank you for helping us all in this fight.
Much love and peace to you , sister
Chris
__________________
Chris in Scotts Valley
June 2002 extensive hi grade DCIS (pre-cancer-stage 0, clean sentinal node) Mastectomy/implant - no chemo, rads. "cured?"
9/2004 Diag: Stage IV extensive liver mets (!) ER/PR- Her2+++
10/04-3/05 Weekly Taxol/Carboplatin/Herceptin , complete response!
04/05 - 4/07 Herception every 3 wks, Continue NED
04/07 - recurrence to liver - 2 spots, starting tykerb/avastin trial
06/07 8/07 10/07 Scans show stable, continue on Tykerb/Avastin
01/08 Progression in liver
02/08 Begin (TDM1) trial
08/08 NED! It's Working! Continue on TDM1
02/09 Continue NED
02/10 Continue NED. 5/10 9/10 Scans NED 10/10 Scans NED
12/10 Scans not clear....4/11 Scans suggest progression 6/11 progression confirmed in liver
07/11 - 11/11 Herceptin/Xeloda -not working:(
12/11 Begin MM302 Phase I trial - bust:(
03/12 3rd times the charm? AKT trial
5/12 Scan shows reduction! 7/12 More reduction!!!!
8/12 Whoops...progression...trying for Perjeta/Herceptin (plus some more nasty chemo!)
9/12 Start Perjeta/Herceptin, chemo on hold due to infection/wound in leg, added on cycle 2 &3
11/12 Poops! progression in liver, Stop Perjeta/Taxo/Herc
11/12 Navelbine/Herce[ptin - try for a 3 cycles, no go.
2/13 Gemzar/Carbo/Herceptin - no go.
3/13 TACE procedure
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06-06-2007, 04:04 PM
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#23
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Senior Member
Join Date: Nov 2005
Location: Ireland
Posts: 3,463
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Sad news Andi
Andi I just logged on and saw your post. What a dreadful decision for anyone to have to make,you had to and you have made it but I truely hate this disease as we all do and wish the situation were different for you. What you've decided to do must require so much more strength and courage than simply continuing with a tx that is having no effect. I'm so glad you have no pain and hope that continues to be the case. Like all the ladies here I respect your view on this but will still be hoping for a turn around at some point for you, whether that be a miracle, a new drug,or simply more peace of mind,I truely wish you everything you would wish for yourself and am so sorry this current tx has 'nt been sucessful. I'll be thinking of you and your family including your sister's dx and hope the situation gets better for all of you.Sorry I can't think of any advice right now other than stay as positive and brave as you are now.
__________________
Tricia
Dx July '05 IDC 1.9cm Triple positive 3/9 nodes positive
A/C X 4 ..Taxol/Herceptin x 12 wks then herceptin 1 yr
Rads x 36 ..oophorectomy August '06
Currently taking Arimidex..
June 2011 osteopenia/ zometa x1 yearly- stopped Zometa 2015 as Dexa show normal bone density.
Stopped Arimidex July 2014- Restarted Arimidex 2015 for a further two years on the advice of my Onc.
2014 Normal Dexa scan
2018 Mammo all clear, still NED!
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06-06-2007, 04:10 PM
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#24
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Senior Member
Join Date: Jul 2006
Location: Shingle Springs, CA - near Sacramento
Posts: 295
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Prayers
Hi Andi,
My prayers are going out to you and your family. Is there anything in the meantime that we as a group can do for your or your family other than pray? Let us know, we are here for you!
Love to you, Donna
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06-06-2007, 04:46 PM
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#25
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Senior Member
Join Date: Sep 2005
Location: Lumberton, Mississippi
Posts: 118
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Oh Andi, I am so sorry.
I will pray for you and your sister in law and other family members at least daily. Prayer does wonder things. It is so sad to hear things like this. Please know that everyone on this list are with you in spirit, with many prayers and good thoughts going for and to you.
I send you love and hugs.
Linda
S. Mississippi
__________________
Diagnosed 12/23/04
Biopsy 12/28/04
Lumpectomy 1/04/05
IDC, ER-PR-, HER2Neu+++
7mm tumor, Stage 1, Grade 3
6 CAF's
38 Rads
Finished 10/05
"Worry looks around. Sorry looks back. Faith looks up."
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06-06-2007, 05:03 PM
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#26
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Senior Member
Join Date: Dec 2005
Posts: 274
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Sending Prayers
Dear Andi,
My thoughts and prayers are with you and your family. I know you have heard the old cliche "where there is life, there is hope". Please try to know that sometimes things can turn around.
Sincerely,
Liz J.
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06-06-2007, 05:49 PM
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#27
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Senior Member
Join Date: Aug 2001
Location: Oregon
Posts: 1,756
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Andi, I am sorry there weren't effective chemos for you. Sometimes, in spite of everything, and all our hopes to the contrary, it's time to let go and make our peace with the world and our maker. It seems like you are well on the way to finding that place and preparing yourself and your family.
I will be keeping you and your family in my thoughts and prayers. Please don't hesitate to post whenever you need to, and we will do our best to help you along.
<3 Lolly
__________________
Sept.'99 - Dx.Stage IIIB, IDC ER/PR-, HER2+++ by IHC, confirmed '04 by FISH. Left MRM, AC x's 4, Taxol x's 4, 33 Rads, finishing Tx May 2000. Jan.'01 - local/regional recurrence, Stage IV. Herceptin/Navelbine weekly till NED August 2001, then maintenance Herceptin. Right Mast. April 2002. Local/Regional recurrence April '04, Herceptin plus/minus chemo until May '07. Gemzar added from Feb.'07-April '07; Tykerb/Abraxane until August '07, back on Herceptin plus Taxotere and Xeloda Sept. '07. Stopped T/X Nov. '07, stopped Herceptin Dec. '07, started Avastin/Taxol/Carboplatin Dec. '07. Progression in chest skin, stopped TAC March '03, started radiation.
Herceptin has served as the "Backbone" of my treatment strategy for over 6 years, giving me great quality of life. In 2005, I was privileged to participate in the University of Washington/Seattle HER2 Vaccine Trial.
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06-06-2007, 06:38 PM
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#28
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Senior Member
Join Date: Sep 2005
Location: Stockton, NJ
Posts: 4,179
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Andi
What about weekly Abraxane with Herceptin and Avastin? Or Abraxane with Herceptin and Tykerb?
I am praying for you and thinking about you.
__________________
Kind regards
Becky
Found lump via BSE
Diagnosed 8/04 at age 45
1.9cm tumor, ER+PR-, Her2 3+(rt side)
2 micromets to sentinel node
Stage 2A
left 3mm DCIS - low grade ER+PR+Her2 neg
lumpectomies 9/7/04
4DD AC followed by 4 DD taxol
Used Leukine instead of Neulasta
35 rads on right side only
4/05 started Tamoxifen
Started Herceptin 4 months after last Taxol due to
trial results and 2005 ASCO meeting & recommendations
Oophorectomy 8/05
Started Arimidex 9/05
Finished Herceptin (16 months) 9/06
Arimidex Only
Prolia every 6 months for osteopenia
NED 18 years!
Said Christopher Robin to Pooh: "You must remember this: You're braver than you believe and stronger than you seem and smarter than you think"
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06-06-2007, 07:01 PM
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#29
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Senior Member
Join Date: Nov 2006
Location: West Virginia
Posts: 105
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Andi,
This has to be really frightening for you. I cannot completely relate, but I can speculate how it would make me feel. You are a strong woman to carry this burden on your shoulders and I will pray for you and your family. I'd love to be able to offer you more than that, but I have found since my own diagnosis that a shoulder to lean on, a hand to hold, a sympathetic ear, and a little prayer can do wonders, even if it is just for your spirit. You are in my thoughts!
Stephanie
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06-06-2007, 07:06 PM
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#30
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Senior Member
Join Date: Dec 2005
Location: Alexandria, VA
Posts: 1,055
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Andi, More hope and prayers for you and your sister. Bev
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06-06-2007, 07:31 PM
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#31
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Senior Member
Join Date: Aug 2003
Location: Morris, IL
Posts: 3,507
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Andi
Please know that you are in my thoughts and prayers each day....I am but a state away if there is anything I can do to help you....this awful disease is not in our hands, and we fight so hard for what has already been determined....sending you my love and hoping for a healing miracle...I want you to be at peace with no pain through all of this.
__________________
"Be kinder than necessary, for everyone you meet is fighting some kind of battle."
Hugs & Blessings
Sheila
Diagnosed at age 49.99999 2/21/2002 via Mammography (Calcifications)
Core Biopsy 2/22/02
L. Mastectomy 2/25/2002
Stage 1, 0.7cm IDC, Node Neg from 19 nodes Her2+++ ER PR Neg
6/2003 Reconstruction W/ Tissue Expander, Silicone Implant
9/2003 Stage IV with Mets to Supraclavicular nodes
9/2003 Began Herceptin every 3 weeks
3/2006 Xeloda 2500mg/Herceptin for recurrence to neck nodes
3/2007 Added back the Xeloda with Herceptin for continued mets to nodes
5/2007 Taken Off Xeloda, no longer working
6/14/07 Taxol/Herceptin/Avastin
3/26 - 5/28/08 Taxol Holiday Whopeeeeeeeee
5/29 2008 Back on Taxol w Herceptin q 2 weeks
4/2009 Progression on Taxol & Paralyzed L Vocal Cord from Nodes Pressing on Nerve
5/2009 Begin Rx with Navelbine/Herceptin
11/09 Progression on Navelbine
Fought for and started Tykerb/Herceptin...nodes are melting!!!!!
2/2010 Back to Avastin/Herceptin
5/2010 Switched to Metronomic Chemo with Herceptin...Cytoxan and Methotrexate
Pericardial Window Surgery to Drain Pericardial Effusion
7/2010 Back to walking a mile a day...YEAH!!!!
9/2010 Nodes are back with a vengence in neck
Qualified for TDM-1 EAP
10/6/10 Begin my miracle drug, TDM-1
Mixed response, shrinking internal nodes, progression skin mets after 3 treatments
12/6/10 Started Halaven (Eribulen) /Herceptin excellent results in 2 treatments
2/2011 I CELEBRATE my 9 YEAR MARK!!!!!!!!!!!!!
7/5/11 begin Gemzar /Herceptin for node progression
2/8/2012 Gemzar stopped, Continue Herceptin
2/20/2012 Begin Tomo Radiation to Neck Nodes
2/21/2012 I CELEBRATE 10 YEARS
5/12/2012 BeganTaxotere/ Herceptin is my next miracle for new node progression
6/28/12 Stopped Taxotere due to pregression, Started Perjeta/Herceptin
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06-06-2007, 08:29 PM
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#32
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Senior Member
Join Date: Dec 2006
Location: Massillon, Ohio
Posts: 247
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I am encouraged by your strength. I feel real strong GIRL POWER from you!!! My heart is breaking and the prayers are coming your way.
__________________
Laurie
Diagonsed 8/10/06 (found own lump)at 35
Her 2 +++, er-/pr-
4 A/C 8-29-06 to 11-06
Lumpectomy, node dissection- 11/30/06
Pathology report stage IIIC
1 tumor 3 cm
10 of 15 nodes +
12 Taxol 12/18/06-03/06/07
Herceptin 12/18/06- 12/11/2007 done!!! yeah!!!
33 rads started 3/22/07, done!! yeah!! 5/07/07
Lymphedema diagonsed 2/1/07
BRCA1/BRCA2 negative
port out 1/10/08
pregnant after 6 yeas of trying- due mid feb.
Ryder David Kessel Hunter born feb.6th 2009
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06-06-2007, 10:11 PM
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#33
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Senior Member
Join Date: Oct 2005
Location: New Jersey
Posts: 3,154
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Dear Andi,
I am so sorry to hear this news...you are a very brave woman and I wish
that another treatment could be tried...please know you are in my prayers
along with your sister in law and your family.
Warmly,
Jean
__________________
Stage 1, Grade 1, 3/30/05
Lumpectomy 4/15/05 - 6MM IDC
Node Neg. (Sentinel node)
ER+ 90% / PR-, Her2+++ by FISH
Ki-67 40%
Arimidex 5/05
Radiation 32 trt, 5/30/05
Oncotype DX test 4/17/06, 31% high risk
TOPO 11 neg. 4/06
Stopped Arimidex 5/06
TCH 5/06, 6 treatments
Herceptin 5/06 - for 1 yr.
9/06 Completed chemo
Started Femara Sept. 2006
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06-06-2007, 10:42 PM
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#34
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Senior Member
Join Date: Mar 2007
Location: Norco, Southern California
Posts: 53
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Andi, I am so sorry to hear your doctors have run out of effective drugs. I am glad you are at peace with your decision and are not in pain. I hope that will continue. I think when we know where we are going, the hardest part is leaving our family behind. Knowing we will meet again gives peace, but still heartache. I am praying for you and your family, and your sister-in-law. God can still do miracles but sometimes He takes us another direction. Either way, know that He is with you.
God bless you.
Beckie
__________________
Diagnosed 4/06, age 55
1.1 cm tumor
Pre-op x-ray caught lung nodules
6/06 - Stage 4, Her2+++, er/pr-
Mets to lungs(largest 3 cm), liver (largest 5.5 cm), and bones
Began taxotere, herceptin, & aredia
7/06 - radiation to lower spine & left shoulder for pain
8/06 - everything smaller
12/06 - stopped taxotere (toe infections)
5/07 - bone mets advancing
6/07 - add navelbine to herceptin & aredia
6/07 - discovered brain mets (3 in cerebellum, largest 2 cm.)
7/07 - WBR, change to Tykerb/Xeloda
9/07 - targeted radiation
10/08 - started navelbine/herceptin
2/09 - brain mets - targeted radiation
5/09 - mets in liver progressing, changed to Ixempra
7/09 - mets in liver still going, to the brain again, on gemzar now
9/09 - gemzar failed, started Doxil today
I know Who holds the future, and I know He holds my hand.
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06-07-2007, 01:21 AM
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#35
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Senior Member
Join Date: Feb 2006
Location: Southern, CA
Posts: 2,511
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Andi, This just breaks my heart. I am at a total loss for words. How I hate this dreaded disease. I can't even imagine how truly difficult all this has been on you and your family. I am going to still pray for a miracle...they do happen. How I wish there was something I could do for you. Please know we are all here for you if there is anything we can do just let us know.
Sending you warm healing thoughts and many prayers.
Chelee
__________________
DX: 12-20-05 - Stage IIIA, Her2/Neu, 3+++,Er & Pr weakly positive, 5 of 16 pos nodes.
Rt. MRM on 1-3-06 -- No Rads due to compromised lungs.
Chemo started 2-7-06 -- TCH - - Finished 6-12-06
Finished yr of wkly herceptin 3-19-07
3-15-07 Lt side prophylactic simple mastectomy. -- Ooph 4-05-07
9-21-09 PET/CT "Recurrence" to Rt. axllia, Rt. femur, ilium. Possible Sacrum & liver? Now stage IV.
9-28-09 Loading dose of Herceptin & started Zometa
9-29-09 Power Port Placement
10-24-09 Mass 6.4 x 4.7 cm on Rt. femur head.
11-19-09 RT. Femur surgery - Rod placed
12-7-09 Navelbine added to Herceptin/Zometa.
3-23-10 Ten days of rads to RT femur. Completed.
4-05-10 Quit Navelbine--Herceptin/Zometa alone.
5-4-10 Appt. with Dr. Slamon to see what is next? Waiting on FISH results from femur biopsy.
Results to FISH was unsuccessful--this happens less then 2% of the time.
7-7-10 Recurrence to RT axilla again. Back to UCLA for options.
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06-07-2007, 05:53 AM
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#36
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Senior Member
Join Date: Apr 2006
Location: Wilmington, Del.
Posts: 1,126
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Thanks for the blessing. God bless you too. Stay comfortable and I hope you can enjoy something every day. You are in my thoughts.
__________________
MJO
IDC, Stage I, Grade 2
Oncotype DX Score 32
Her2++ E+P+, Node Neg.
Lumpectomy 11/04/05 Clear Margins
3 Dose dense AC (Couldn't tolerate 4)
4 Dose dense Taxol & Herc. (Tolerated well)
36 weeks Herceptin (Could not complete one year due to decrease in MUGA score)
2 years of Arimidex, then three years of Femara
Finished Femara May 2011
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06-07-2007, 07:45 AM
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#37
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Senior Member
Join Date: Mar 2006
Location: IOWA
Posts: 243
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This decision was a very hard one to make. When my cancer recurred, the labs on the new cancer showed no longer was I estrogen positive and that my her2 status was a 2+ by the one test but a 0 by Fish, so I really lost 2 of my strongest weapons. We stilled tried the herceptin and the tykerb along with the other chemos, but to no avail. My oncologist is very on top of his game and has also discussed my case with other tops in the b/c field. He was a Brinker award winner in 2002 and I believe his area was something to do with reducing the side effects of treatment. He never told me I had to stop, he said he would do whatever I wanted,but we have always had a relationship that was totally honest between us, yet he was always very sensitive and gentle. I could ask him anything and he would always give me a straight answer. He has called me once a week since I made this decision to see how I am getting along. I am still praying for a miracle but I know my time is short. If anyone has any questions at all about my situation, etc, please feel free to ask. I have always valued the openess and sharing that has taken place on this site, if I can contribute to that I would be more than happy to.
__________________
Andi
-- ------------------------
Stage IIIC, 17 of 20 Nodes +, E+, Her2+++
Diagnosed 6/30/05
Lumpectomy 7/13/05
Dose Dense A/C x 4
Weekly Taxol + Herceptin x 12
Remainder of year Herceptin Every 3 weeks (completes 9/13/06)
Radiation completed 2/28/06
Currently on Tamoxifen
Dec 06 - Pleural effusion treated with pleurodesis
Now er/pr-, her2++
1/07 started weekly Navelbine plus Herceptin
Discontinued Tamoxifen
4/27/07 CTshowed progression
5/01/07 Began Tykerb/Xeloda + Zometa
5/22/07 Stopped treatment due to great progression
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06-07-2007, 08:04 AM
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#38
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Senior Member
Join Date: Sep 2005
Location: Ohio
Posts: 212
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Andi, how selfless of you to think of us on this board and welcome our questions now. Are you getting hospice care? I hope you and your family are surrounded by deep peace and love. I'll keep you in my prayers.
__________________
Audrey
diagnosed July 2001, at age 36
large tumor, 11+ nodes
Stage IIIb, er/pr-, Her2+
treated with A/C, weekly Taxol
radiation, + year of Herceptin
on clinical trial. double mastectomy
followed by reconstruction
NED!!
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06-07-2007, 08:47 AM
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#39
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Senior Member
Join Date: Sep 2005
Posts: 556
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Andi,
Please don't give up. Can you try other chemos left? Some times miracles might happen and that particular chemo might be the one which saves you. Thinking of you.
Julie
__________________
Diagnosed in Sept 2004 while pregnant with the second child. Stage 3b, tumor 4.5cm, 4 auxillary and supraclav node positive. Her2+++ FISH 9.4 and er-,pr-.
Had dose dense neoadjuvant AC,Taxol then mastectomy,radiation+xeloda+Herceptin.
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06-07-2007, 01:13 PM
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#40
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Senior Member
Join Date: Sep 2005
Location: NYC
Posts: 250
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Dear Andi,
I've not really known what to write, and I'm so sorry that your journey has taken this turn. I've always wondered what I would do if faced with the challenges that you've confronted and I hope I approach it as bravely and as openly as you are.
For all the drugs that we have, now and in the pipeline, for all the pink ribbons, the truth is there is no cure for breast cancer. It breaks my heart that there aren't better answers for you.
I hope you remain painfree and that your journey, wherever it may lead you, is one that is peaceful and full of love, family and friends.
My best,
Jen
__________________
dx 4/05 @ 34 y.o.
Stage IIIC, ER+ (90%)/PR+ (95%)/HER2+ (IHC 3+)
lumpectomy-- 2.5 cm 15+/37 nodes
(IVF in between surgery and chemo)
tx dd A/C, followed by dd Taxol & Herceptin
30 rads (or was it 35?)
Finished Herceptin on 7/24/06
Tamox
livingcured.blogspot.com
"Keep your face to the sunshine and you cannot see the shadow." -- Helen Keller
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