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Old 09-28-2010, 03:23 PM   #1
bejuce
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What should ER+/PR- breast cancer patients/survivors eat?

Hi everyone,

I just found this link and thought I would pass it along. The link gives specific guidelines on what foods to avoid and which ones to eat when you are ER+/PR-.

The link also provides references to studies that showed significant associations between carbohydrate intake, glycemic index and glycemic load and higher risk of ER+/PR- breast cancer. The link also states that ER+/PR- breast cancer patients may be more likely than ER+/PR+ patients to benefit from epidermal growth factor receptor (EGFR) inhibitors.

Sounds like those of us that are ER+/PR- may have additional (i.e. nutritional) tools at our disposal to reduce our odds of recurrence.
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ER+ (30%)/PR-/HER-2+, stage 3

Diagnosed on 02/18/09 at 38 with a huge 12x10 cm tumor, after a 6 month delay. Told I was too young and had no risk factors. Found swollen node during breastfeeding.
March-August 09: neo-adjuvant chemo, part of a trial at Stanford (4 DD A/C, 4 Taxotere with daily Tykerb), loading dose of Herceptin
08/12/09 - bye bye boobies (bilateral mastectomy)
08/24/09 - path report shows 100 % success in breast tissue (no cancer there, yay!), 98 % success in lymphatic invasion, and even though 11/13 nodes were still positive, > 95 % of the tumor in them was killed. Hoping for the best!
September-October 09: rads with daily Xeloda
02/25/10 - Cholecystectomy
05/27/10 - Bone scan clear
06/14/10 - CT scan clear, ovarian cyst found
07/27/10 - Done with Herceptin!
02/15/11 - MVA-BN HER-2 vaccine trial
03/15/11 - First CA 15-3: 12.7 and normal, yay!
10/01/11 - Bone scan and CT scan clear, fatty liver found
now on Tamoxifen and Aspirin


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Old 09-28-2010, 06:39 PM   #2
Becky
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Re: What should ER+/PR- breast cancer patients/survivors eat?

I am also Er+ and PR-. I try to eat right (like on the list) but do eat treats when appropriate.

Remember that this article is saying that if you are ER+ but PR-, something else is also driving your cancer. In our case, that is most likely Her2. EGFR is also know as Her1. We all could be Her1+ too but there is more to worry about if you are ER+PR- but NOT Her2+ because it opens the door on what else you are positive for (because ER likes another partner to play with while Her2 will play with anyone, even itself

The list is a good one but is really saying "eat a plant based diet - lots of veggies etc". Stay clear of white foods and sweets.
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Kind regards

Becky

Found lump via BSE
Diagnosed 8/04 at age 45
1.9cm tumor, ER+PR-, Her2 3+(rt side)
2 micromets to sentinel node
Stage 2A
left 3mm DCIS - low grade ER+PR+Her2 neg
lumpectomies 9/7/04
4DD AC followed by 4 DD taxol
Used Leukine instead of Neulasta
35 rads on right side only
4/05 started Tamoxifen
Started Herceptin 4 months after last Taxol due to
trial results and 2005 ASCO meeting & recommendations
Oophorectomy 8/05
Started Arimidex 9/05
Finished Herceptin (16 months) 9/06
Arimidex Only
Prolia every 6 months for osteopenia

NED 18 years!

Said Christopher Robin to Pooh: "You must remember this: You're braver than you believe and stronger than you seem and smarter than you think"
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Old 09-28-2010, 06:59 PM   #3
Rich66
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Re: What should ER+/PR- breast cancer patients/survivors eat?

The article makes a good point about the variability between primary and mets. Same for Her2. It is a bit frustrating to keep seeing soy products for ER+ when in ER+/Her2+ soy may still be a problem.
Seems like sugar/starches, meats, dairy and soy are, given uknown drivers at any given time, in the risk category. Along with coffee (ducks)
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Old 09-28-2010, 08:11 PM   #4
joletta
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Re: What should ER+/PR- breast cancer patients/survivors eat?

Great article bejuice.
Does anyone know of any specific type of food to keep the Her2 from not recurring or any supplement(s), vitamin that may help with that. Does her2 have anything to do w/the foods that we eat?
Joletta
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dx- march 2010 age 35 stage 3a 4 of 9 pos. nodes
idc 2.2 ininvasive 7cm of dcis er/pr- her2+
april 15 2010 bilateral masectomy w/ tissue expanders
may 4 2010 port import
may 6 2010 clean ct scan & bone scan
may 11 2010 start 4 A/C (finish aug 3 2010)
aug 17 2010 start weekly herceptine & taxol 12xs (end date of oct 19 2010)
nov-dec 2010 30 radation
(plan permanent implants for feb or mar 2011)
continue on herceptine till aug 2011

Love & prayers to everyone
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Old 09-28-2010, 08:41 PM   #5
ElaineM
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Wink Re: What should ER+/PR- breast cancer patients/survivors eat?

Thanks for the article. Whatever we learn to help ourselves is a plus. I posted some information and links in the nutrition forum. One post is about foods that have some aromatase inhibiting or estrogen blocking properties. The other post is about foods that are anti angiogenesis. There are several other articles in the nutrition forum that might interest you.
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ElaineM
12 years and counting
http://her2support.org/vbulletin/showthread.php?t=48247
Lucky 13 !! I hope so !!!!!!
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14 Year Survivor
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Old 09-29-2010, 12:39 AM   #6
harrie
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Re: What should ER+/PR- breast cancer patients/survivors eat?

Do not overdo the soy products.
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*** MARYANNE *** aka HARRIECANARIE

1993: right side DCIS, lumpectomy, rads
1999: left side DCIS, lumpectomy, rads, tamoxifen

2006:
BRCA 2 positive
Stage I, invasive DCIS (6mm x 5mm)
Grade: intermediate
sentinal node biopsy: neg
HER2/neu amplified 4.7
ER+/PR+
TOPO II neg
Oncotype dx 20
Bilat mastectomy with DIEP flap reconstruction
oophorectomy

2007:
6 cycles TCH (taxotere, carboplatin, herceptin)
finished 1 yr herceptin 05/07
Arimidex, stopped after almost 1 yr
Femara
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