 |
|
03-19-2010, 01:58 PM
|
#21
|
|
Member
Join Date: Mar 2010
Location: Bucharest, Romania
Posts: 20
|
Re: Mets to bone
Hello Lucian!
Chiar ca e foarte mica lumea!
How small the world is. What a nice surprise. How are you?
Kisses,
Felicia
__________________
24.06.2009 - DX: Multicentric breast cancer stage IV with bone metastases, IDC grade 3, ER-/PR-, Her2/Neu +++, FISH +, proliferation index high (Ki67 50%), Richardson scale 8 of 9
01.07.2009 - 3 courses chemotherapy: Taxotere 75mg/m2 + Carboplatin AUC 6 + Herceptin 6 mg/kg - every 21 days; Zometa 4mg - every 28 days for bone metastases
01.09.2009 - Right modified radical mastectomy, including 16 axilla nodes (3 positive).
22.09.2009 - Another 3 courses chemotherapy: Taxotere 75mg/m2 + Carboplatin AUC 6 + Herceptin 6 mg/kg - every 21 days; Zometa 4mg - every 28 days for bone metastases
02.12.2009 - PET/CT images shows no evidence of malignant tissue on the whole body
8.12.2009 - start radiotherapy 30 sessions
Herceptin and Zometa still
15.06.2010 - NED!!!
My story at: http://feliciaenache.blogspot.com/20...estea-mea.html
|
|
|
|
03-19-2010, 02:54 PM
|
#22
|
|
Member
Join Date: Mar 2010
Location: Bucharest, Romania
Posts: 20
|
Re: Mets to bone
Thank you very much Jacqueline!
Best wishes,
Felicia
__________________
24.06.2009 - DX: Multicentric breast cancer stage IV with bone metastases, IDC grade 3, ER-/PR-, Her2/Neu +++, FISH +, proliferation index high (Ki67 50%), Richardson scale 8 of 9
01.07.2009 - 3 courses chemotherapy: Taxotere 75mg/m2 + Carboplatin AUC 6 + Herceptin 6 mg/kg - every 21 days; Zometa 4mg - every 28 days for bone metastases
01.09.2009 - Right modified radical mastectomy, including 16 axilla nodes (3 positive).
22.09.2009 - Another 3 courses chemotherapy: Taxotere 75mg/m2 + Carboplatin AUC 6 + Herceptin 6 mg/kg - every 21 days; Zometa 4mg - every 28 days for bone metastases
02.12.2009 - PET/CT images shows no evidence of malignant tissue on the whole body
8.12.2009 - start radiotherapy 30 sessions
Herceptin and Zometa still
15.06.2010 - NED!!!
My story at: http://feliciaenache.blogspot.com/20...estea-mea.html
|
|
|
|
|
03-19-2010, 03:55 PM
|
#23
|
|
Senior Member
Join Date: May 2006
Location: California
Posts: 668
|
Re: Mets to bone
Undecided,
We would like to know your name...
I asked the same question to my onc., he said that it's possible to be Negative the firs time around and after 5-7 years it will change to Positive...but he said that once you test from----to--- it's highly unllikely for the tumor to mutate once again...I did not quite believe it but it does make sense. He said that down the road ---if needed--we (him and I) will have a new hormone test done--- but it's not likely I will need it.
Complicated...If you are unsure I guess you can ask your doctor and have it done just to make sure it has not mutate again.
Take care,
Adriana
__________________
1994 - rt brst, .lump, underarm node dissection,chemo+rad 1.2 cms, Grade 3.
28 nodes neg
Er,Pr, Positive HER2 status unknown
2003- Recur to rt lung.July 16 ( B-Day!)
Her2+++ Er,Pr, Negative
2003 - Aug04--Navelbine + Herceptin
2004- 2007--NED - Herceptin, only
2007 Feb-April Xeloda added to hereceptin
2007-May Back on Navelbine+Herceptin
2008-Feb-Mar 15 Ses Rad to Rt. Lung
2008- Oc 17 Add Tykerb to Herceptin
2009- June-- Discont Tykerb
2009 July 7--Current Taxol + Herceptin
2009 Dec--Discontinued treatment due to progression. Looking into cyberknife.
2010-Aug Accepted to TDM1, no SE, except liver count went up.
2010-2011 September got kicked out of the trial, due to a small spot found on lung.
2011- 2012 September thru early 2013 on Herceptin
2013- March Bone density shows small spot on 5th rib.
2013 - April 4th appt with onc. will post after discussing course of treatment.
2013-March-April Cyber knife to brain and radiation to rib. Chest --base line before chemo-CT-Scan stable for lung issue. CA2729 Normal.
2013 April Herceptin- TDMI
2013 Sept Herceptin + Perjeta . CA2729 within normal range. Brain and Pet scans October 31st. will post results.
2013 October Brain MRI- mixed response. Will see Onc/rad on Halloween.
2013 October/November Brain-MRI nothing new. Repeat MRI next year in May.
2013 December Continue Herceptin and Perjeta. Stable at the moment.
2014 February Brain MRI -clear!
2014 January Added Taxotere to Perjeta+Herceptin.
2014 March Stopped chemo-chest ct-scan next.
2014- March Scans shows tumor's larger, CA2729 higher. Discontinue Herceptin.
2014 April Perjeta+ Halaven
2014 April CA2729 went down 60 points after one cycle. Cough does not want to go away.
2014 June Continue on Perjeta + Halaven-- no more cough. Stable
2014 June Back on Herceptin + abraxane
|
|
|
|
|
03-19-2010, 04:02 PM
|
#24
|
|
Senior Member
Join Date: May 2006
Location: California
Posts: 668
|
Re: Mets to bone
Lopsided..
I took a break ---3 months to be exact...there was progression --small but nothing to be afraid of. I will be going back to chemo---Gemzar possibly--and I know it will work again. Maybe TDMI trial..Not sure. I will post as soon as I find out.
I am on the side of taking small chemo breaks, to give your body and cells a rest...You are not going to have a disastorous? outcome by taking a small break.
In the past I was afraid just like you..Not anymore, taking breask has renewed me. Ask your doctor.
Take care,
Adriana
__________________
1994 - rt brst, .lump, underarm node dissection,chemo+rad 1.2 cms, Grade 3.
28 nodes neg
Er,Pr, Positive HER2 status unknown
2003- Recur to rt lung.July 16 ( B-Day!)
Her2+++ Er,Pr, Negative
2003 - Aug04--Navelbine + Herceptin
2004- 2007--NED - Herceptin, only
2007 Feb-April Xeloda added to hereceptin
2007-May Back on Navelbine+Herceptin
2008-Feb-Mar 15 Ses Rad to Rt. Lung
2008- Oc 17 Add Tykerb to Herceptin
2009- June-- Discont Tykerb
2009 July 7--Current Taxol + Herceptin
2009 Dec--Discontinued treatment due to progression. Looking into cyberknife.
2010-Aug Accepted to TDM1, no SE, except liver count went up.
2010-2011 September got kicked out of the trial, due to a small spot found on lung.
2011- 2012 September thru early 2013 on Herceptin
2013- March Bone density shows small spot on 5th rib.
2013 - April 4th appt with onc. will post after discussing course of treatment.
2013-March-April Cyber knife to brain and radiation to rib. Chest --base line before chemo-CT-Scan stable for lung issue. CA2729 Normal.
2013 April Herceptin- TDMI
2013 Sept Herceptin + Perjeta . CA2729 within normal range. Brain and Pet scans October 31st. will post results.
2013 October Brain MRI- mixed response. Will see Onc/rad on Halloween.
2013 October/November Brain-MRI nothing new. Repeat MRI next year in May.
2013 December Continue Herceptin and Perjeta. Stable at the moment.
2014 February Brain MRI -clear!
2014 January Added Taxotere to Perjeta+Herceptin.
2014 March Stopped chemo-chest ct-scan next.
2014- March Scans shows tumor's larger, CA2729 higher. Discontinue Herceptin.
2014 April Perjeta+ Halaven
2014 April CA2729 went down 60 points after one cycle. Cough does not want to go away.
2014 June Continue on Perjeta + Halaven-- no more cough. Stable
2014 June Back on Herceptin + abraxane
|
|
|
|
|
03-20-2010, 04:40 AM
|
#25
|
|
Senior Member
Join Date: Oct 2006
Location: Fredericksburg, VA
Posts: 93
|
Re: Mets to bone
Hi Lopsided,
I have mets to my bones, that's really the only place, all through my spine and hips. I finished abraxane/herceptin in November and it took care of the couple lymph nodes that went active, but I had progression in my bones. I had not been doing zometa for a while due to concerns about side effects (specifically jaw bone deterioration) but have started it again and hope it will work as well as it has in the past. I haven't had radiation to my bones, we've approached it twice and have decided to go with more systemic treatment. The initial radiation to my breast left me more tired/exhausted than any of the chemos I've done.
I know I've aged a lot since chemo and being menopausal. I have an identical twin sister (no BC for her thank god), and so seeing pictures of us together or the few times a year we get to visit is sort of painful because it's really "in my face" how much older I look than she does. It really makes me sad, so I just remind myself I'm happy to have hair (for now) and of all the wonderful things that have come from having BC, and I remember I'd rather have the wonderful things - like being closer to my husband and having a much deeper spiritual life.
Peace and Blessings,
__________________
Liz
3/05 Initial dx invasive dc 2 cm lump, age 39
lumpectomy & 3 of 5 nodes +, ER+/PR+, Her2+++
alternative chemo 5/05-7/05, rad 8/05-10/05
7/06 dx mets to vertebrae, pelvis & chest lymph nodes
8/06 - 10/06 tamoxifen, herceptin, oophorectomy & zometa
11/06 PET/CT showed continued bone mets, new spot on liver
12/06 began taxotere/herceptin 1x/3 weeks,
2/07 - 2-08 NED!
3/08 progression, start taxol/herceptin weekly, monthly zometa
8/08 start ai & herceptin
12/08 - progression, start weekly navelbine/herceptin thru 6/09 & monthly zometa
7/09 - PET/CT showed improvement in spine, but 2-3 lymph nodes in chest became active
9/09 - 11/09 - weekly abraxane/herceptin
12/09 - PET/CT - chest lymph nodes resolved, progression in spine & pelvis
2/10 - 6/10 - start tykerb/xeloda, progession in spine & pelvis
7/10 - start taxotere/carboplatin/herceptin
|
|
|
|
|
03-23-2010, 03:00 PM
|
#26
|
|
Member
Join Date: Mar 2010
Location: Bucharest, Romania
Posts: 20
|
Re: Mets to bone
Hi Virginia,
I also have the same problem. I looked at some pictures on 2 years ago and even last year and I did not believe it how much I've aged in the 9 months since I discovered that I had cancer. Chemotherapy, pain and despair have left deep marks on my face. And I'm so sad too. I look 10 years older now.
Felicia
__________________
24.06.2009 - DX: Multicentric breast cancer stage IV with bone metastases, IDC grade 3, ER-/PR-, Her2/Neu +++, FISH +, proliferation index high (Ki67 50%), Richardson scale 8 of 9
01.07.2009 - 3 courses chemotherapy: Taxotere 75mg/m2 + Carboplatin AUC 6 + Herceptin 6 mg/kg - every 21 days; Zometa 4mg - every 28 days for bone metastases
01.09.2009 - Right modified radical mastectomy, including 16 axilla nodes (3 positive).
22.09.2009 - Another 3 courses chemotherapy: Taxotere 75mg/m2 + Carboplatin AUC 6 + Herceptin 6 mg/kg - every 21 days; Zometa 4mg - every 28 days for bone metastases
02.12.2009 - PET/CT images shows no evidence of malignant tissue on the whole body
8.12.2009 - start radiotherapy 30 sessions
Herceptin and Zometa still
15.06.2010 - NED!!!
My story at: http://feliciaenache.blogspot.com/20...estea-mea.html
|
|
|
|
|
03-23-2010, 08:32 PM
|
#27
|
|
Senior Member
Join Date: Dec 2006
Location: Oregon
Posts: 715
|
Re: Mets to bone
Hi Sheila,
Hey it is okay to whine. I think you sound very bright and very brave. I only had 12 weeks of chemo, and I still feel the fatigue and some of the other things I like to complain about.
Take care and all the best,
Catherine
__________________
Catherine
Found my own lump in the shower
April 2006 at the age of 58
Stage IIB, ER- PR- HER2+++ multi focal tumors, largest 2.3cm
Chemo first: AC/Taxol over 16 weeks
Bilateral mastectomy Sep 06
33 rads after the surgery
1 year of Herceptin completed Dec 07
15 years and no recurrence as of April 2021
|
|
|
|
Posting Rules
|
You may not post new threads
You may not post replies
You may not post attachments
You may not edit your posts
HTML code is Off
|
|
|
All times are GMT -7. The time now is 10:49 PM.
|
Linear Mode
