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11-07-2007, 05:45 AM
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#21
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Senior Member
Join Date: Feb 2006
Location: Acworth, GA
Posts: 2,104
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Christine,
That's wonderful news! You are an encouragement to all of us.
__________________
Kate
Stage IIIC Diagnosed Oct 25, 2005 (age 58)
ER/PR-, HER2+++, grade 3, Ploidy/DNA index: Aneuploid/1.61, S-phase: 24.2%
Neoadjunct chemo: 4 A/C; 4 Taxatore
Bilateral mastectomy June 8, 2006
14 of 26 nodes positive
Herceptin June 22, 2006 - April 20, 2007
Radiation (X35) July 24-September 11, 2006
BRCA1/BRCA2 negative
Stage IV lung mets July 13, 2007 - TCH
Single brain met - August 6, 2007 -CyberKnife
Oct 2007 - clear brain MRI and lung mets shrinking.
March 2008 lung met progression, brain still clear - begin Tykerb/Xeloda/Ixempra
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11-07-2007, 06:24 AM
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#22
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Senior Member
Join Date: Jun 2007
Location: RHODE ISLAND
(Ed getting me a latte on 2nd Cancerversary Cruise 2008)
'BELIEVE': To accept as true or real, To have faith in, To presume
ALWAYS BELIEVE
Posts: 2,999
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Yessir!!
Oh Christine, how this news has made me all warm and happy inside. You are such an inspiration to all of the lives you touch, you are the true meaning of warrior and have taught us so very much about how to go forward with this unbelievable journey. Thanks for the inspiration and for this glorious site we are honored to call home. Thanks for having this family come together to fight this fight with all that we have and all we must muster up to win. And most importantly, thanks for being Christine, you are by far one of my greatest hero's. KUDO's Lovey....KUDO's!! Continued success beating the beast!!>>Believe51
__________________
9/7/06Husband 50yrs=StageIV IBC/HER2+,BoneMets10/06TaxotereX10,'H'1X wk,Zometa,Tamoxifen4/12/07Last Tax5/18/07Pet=Rapid Cell Activity,No Organ Mets,Lytic Lesions,Degeneration,Some Bone Repair5/07ChemoFail6/01/07Pleural Thoracentisis=Effusions,NoMalignantCells6/19/07+7/2/07DFCI
6/25/07BrainMRI=BrainMets,Many<9mm7/10/07WBR/PelvisRad37.5Gx15&Nutritionist8/19/07T/X9/20/07BrainMRI=2<2mm10/6/07Pet=BoneProgression
10/24/07ChemoFail11/9/07A/Cx10,EndTam12/7/07Faslodex12/10/07Muga7512/13/07BlasticLesions1/7/08BrainMRI=Clear4/1/08Pet=BoneImprovement,
NoProgression,Stable4/7/08BrainPerfect5/16/08Last A/C8/26/08BrainMets=10(<9mm)9/10/08Gamma10/30/08Met=5mm12/19/08Gamma5mets5
12/22/08SpinalMets1/14/09SpinalRads2/17/09BrainMRI=NoNewMets4/20/09BoneScan5/14/09Ixempra6/1/09BrainMRI=NumerousMets6/24/09DFCIw/DrBurstein6/26/09Continue
Ixempra/Faslodex/Zometa~TM now lower7/17/09Stop Ixempra By Choice9/21/09HOSPICE10/16/09Earned His Deserved Wings And Halo=37 Month Fight w/Stage 4 IBC, Her2+++,My Hero!!
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11-07-2007, 06:27 AM
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#23
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Senior Member
Join Date: Sep 2005
Location: Central Florida
Posts: 503
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Onward and forward , oh fearless one !!!
An early Christmas gift !
Maria
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11-07-2007, 06:55 AM
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#24
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Senior Member
Join Date: May 2007
Location: Northern Michigan
Posts: 68
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More implosion to you!
Congratulations Christine, you are a true inspiration to us all!
Love & hugs
Michelle
__________________
Sept. 2003- 5cm tumor in left breast Her2+ Er- Pr- grade 3,
Mastectomy & 11 nodes removed, all negative.
4 rounds A/C + 12 wky Taxol
25 rads
Dec 2006- recurrence Stage IV (diagnosed 3 days before Christmas!) Lymph nodes in chest, liver, 3 ribs
January 2007- 3 tri wkly rounds of Taxol/Herceptin
Response to lymph nodes in chest, but several more bone mets (skull, shoulders, more ribs, femur, several on spine), liver tumors still growing.
March 2007- 8 wkly rounds of Navelbine/Herceptin/ every 4th wk Zometa
Lymph nodes in chest look great, but more bone mets (of course!), Clavicles, hips, and sacrum (above tail bone) to add to the list. Liver mets still growing.
June 5- started Tykerb/Xeloda
Aug 14- Scans are showing great progress! Tumor shrinkage and bones are healing!
Nov 21 CT scan shows tumor growth in liver & bones next Doc appt on 11-27
Dire need of a lot of prayers and a miracle.
Stay at home mom, 5 yr old girl & 8 yr old boy.
Wife of loving husband
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11-07-2007, 07:01 AM
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#25
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Senior Member
Join Date: Sep 2005
Location: france
Posts: 1,648
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Christine,
congrats on the great news!!! you of all people deserve good news.
This is a wonderful site.
love sarah
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11-07-2007, 07:45 AM
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#26
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Senior Member
Join Date: Aug 2006
Location: Poland Ohio just a little south of Youngstown.
Posts: 473
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So happy to hear this report, Christine. Like everyone else here, I so appreciate you, your husband and this wonderful site. You are always in my prayers.
Hugs
__________________
Susan
Age: 61
dx: 5/25/06
2 cm/ 0 nodes
Lumpectomy rt breast on 7/26/06
ER/PR- / Her2+++
A/C x 4
finished taxotere 2/07
finished 33 rads
Herceptin finished 12/07/07 Yippee!
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11-07-2007, 08:08 AM
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#27
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Senior Member
Join Date: Sep 2005
Location: OH
Posts: 385
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I/We could not be happier for you...what an inspiration you are.
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11-07-2007, 08:37 AM
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#28
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Senior Member
Join Date: Oct 2005
Location: New Jersey
Posts: 3,154
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Christine,
Now, you have "made my day"....
Just keep that beautiful smile of yours going!
Continued Blessings,
Jean
__________________
Stage 1, Grade 1, 3/30/05
Lumpectomy 4/15/05 - 6MM IDC
Node Neg. (Sentinel node)
ER+ 90% / PR-, Her2+++ by FISH
Ki-67 40%
Arimidex 5/05
Radiation 32 trt, 5/30/05
Oncotype DX test 4/17/06, 31% high risk
TOPO 11 neg. 4/06
Stopped Arimidex 5/06
TCH 5/06, 6 treatments
Herceptin 5/06 - for 1 yr.
9/06 Completed chemo
Started Femara Sept. 2006
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11-07-2007, 08:48 AM
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#29
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Senior Member
Join Date: Sep 2005
Location: Riverside, CA
Posts: 484
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Christine, that is great news! So glad the Gamma knife did it's job, relax and have some fun now.
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11-07-2007, 10:44 AM
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#30
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Senior Member
Join Date: Feb 2007
Location: Paris, France
Posts: 858
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Christine,
I just read your post and have a big smile on my face. I know you must have one too! I know we were all thinking of you. So it is a very very sunny day!
Michka
__________________
08.2006 3 cm IDC Stage 2-3, HER2 3+ ER+90% PR 20%
FEC, Taxol+ Herceptin, Mastectomy, Radiation, Herceptin 1 year followed by Tykerb 1 year,Aromasin /Faslodex
12.2010 Mets to liver,Herceptin+Tykerb
03.2011 Liver resection ER+70% PR-
04.2011 Herceptin+Navelbine+750mg Tykerb
06.2011 Liver ned, Met to sternum. Added Zometa 09.2011 Cyberknife for sternum
11.2011 Pet clear. Stop Navelbine, continuing on Hercpetin+Tykerb+Aromasin
02.2012 Mets to lungs, nodes, liver
04.2012 TDM1, Ned in 07.2012
04.2015 Stop TDM1/Kadcyla, still Ned, liver problems
04.2016 Liver mets. Back on Kadcyla
08.2016 Kadcyla stopped working. mets to liver lungs bones
09.2016 Biopsy to liver. no more HER2, still ER+
09.2016 CMF Afinitor/Aromasin/ Xgeva.Met to eye muscle Cyberknife
01.2017 Gemzar/Carboplatin/ Ibrance/Faslodex then Taxotere
02.2017 30 micro mets to brain breathing getting worse and worse
04.2017 Liquid biopsy/CTC indicates HER2 again. Start Herceptin with Halaven
06.2017 all tumors shrunk 60% . more micro mets to brain (1mm mets) no symptoms
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11-07-2007, 10:47 AM
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#31
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Senior Member
Join Date: Apr 2006
Location: Boston
Posts: 66
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Hooray, Christine! Fabulous news! More power to you!
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11-07-2007, 11:04 AM
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#32
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Senior Member
Join Date: Sep 2007
Location: Tampa, FL
Posts: 43
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Christine,
That is wonderful news. I'm a newbie here, and just wanted to take a moment and thank you and your husband for such a great board. It is truly a blessing to read about so much of what I'm going through and all the knowledge that the people here have. I've learned so much.
God bless.
Verna
__________________
stage IV, diagnosed Nov.11,2005
mets to spine,hips,pelvic,femur
4 a/c
mastectomy Feb.14,2006
4 taxol
mets to liver
5 weeks radiation
Herceptin/Zometa
reconstruction Feb.14,2007 (DEIP)
Tykerb/Xeloda
TDM1 study
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11-07-2007, 11:06 AM
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#33
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Senior Member
Join Date: Sep 2007
Location: Tampa, FL
Posts: 43
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Christine,
That is wonderful news, praise God. I'm a newbie here, and just wanted to thank you and your husband for such a great board.
Verna
__________________
stage IV, diagnosed Nov.11,2005
mets to spine,hips,pelvic,femur
4 a/c
mastectomy Feb.14,2006
4 taxol
mets to liver
5 weeks radiation
Herceptin/Zometa
reconstruction Feb.14,2007 (DEIP)
Tykerb/Xeloda
TDM1 study
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11-07-2007, 11:07 AM
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#34
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Senior Member
Join Date: Sep 2007
Location: Tampa, FL
Posts: 43
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ok, so the first one did post....
__________________
stage IV, diagnosed Nov.11,2005
mets to spine,hips,pelvic,femur
4 a/c
mastectomy Feb.14,2006
4 taxol
mets to liver
5 weeks radiation
Herceptin/Zometa
reconstruction Feb.14,2007 (DEIP)
Tykerb/Xeloda
TDM1 study
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11-07-2007, 11:16 AM
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#35
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Senior Member
Join Date: Aug 2007
Location: Silicon Valley, CA
Posts: 76
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brain MRI results A-OK
Hi, Christine -
Whew - such good news! How did your oncologist and/or radiation onc know that the "tumor had grown slightly" on your previous set of scans?
I'm in a similar position, though the jury is still out about the nature of a very slowly-growing "spot" deep in the right caudate/ basal ganglia section of my brain, where CyberKnife had been done for a .5cm spot, back in July 05.
Ever since routine quarterly brain scans in October 06, the same spot reappeared, and has been growing by approx. 2mm/quarter. Radiation onc, neurosurgeon and neuro-onc cannot determine if the "spot" represents radiation injury (necrosis/scarring) or indolently growing cancer cells. I started on Tykerb, in addition to Herceptin, on July 1, and was hoping that, if the "spot" were actually cancer cells, there would have been shrinkage on my last set of scans. Alas, instead there was another 2mm increase in just one direction - and no one is willing to hazard a more definitive guess at its derivation.
So, I keep hoping that one of these days (next MRI brain scans are due in Dec.), there'll be shrinkage, whether b/c the Tykerb is working and it WAS bcmets regrowth, or b/c the necrotic cells are being reabsorbed and disappearing.
In any case, your scan results give me hope that maybe mine will also show shrinkage with the next set! Thanks!
(((hugs)))
Sandy in Silicon Valley
__________________
1992 - age 44/ ER-/PR+ Stage II dx - mastectomy, CAF x 6 cycles; Tamoxifen
1997 - BRCA1 mutation dx'd
1998 - ovaries removed
1999 - off Tamoxifen, on Arimidex
2003 - dx'd Stage IV - lymph nodes & lungs. ER-/PR-/HER2neu+++.
Tx: Herceptin & Taxotere (6 cycles).
2005 - 2.9cm x 3.6cm brain tumor. Craniotomy, CyberKnife. 9 mo. staph aureus infection at incision site - 2nd craniotomy. Two small brain mets CyberKnife'd.
2006 - revisit Xeloda - dosage lowered to 2500mg/day, 5 cycles.
2007 - "spot" dx'd on qtrly brain MRI - same location as CyberKnife 7/05. > by 2-4mm per quarter - - radiation injury or re-growing cancer? Tykerb added to Herceptin - July, still "watching & waiting". Otherwise, fully functional...
"The majority of people are not only afraid of holding a wrong opinion, they are afraid of holding an opinion alone." Kierkegaard
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11-07-2007, 11:19 AM
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#36
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Senior Member
Join Date: Aug 2006
Location: So California
Posts: 223
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Congratulations!
Great news Christine! I'm celebrating with you. As a side note I have to thank you and Joe again for a wonderful site. I have checked other sites and this is BY FAR the easiest site to navigate. We all appreciate you so much.
__________________
Leslie's Sister (Lisa)
Diagnosed 5/17/06
Left breast Stage II
5 cm. Her2Neu+++, ER-, PR-
1 positive node out of six,
double mastectomy 6/9/06;
TCH started 7/12/06
last chemo 10/25/06
herceptin ended 6-11-07
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11-07-2007, 11:26 AM
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#37
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Senior Member
Join Date: Jun 2006
Location: South Florida
Posts: 477
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Christine,
That is GREAT news!
Carolyn
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11-07-2007, 02:16 PM
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#38
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Senior Member
Join Date: Sep 2005
Location: Vancouver, Canada
Posts: 329
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Great news, I'm so happy for you.
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11-07-2007, 03:53 PM
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#39
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Senior Member
Join Date: Sep 2005
Location: Central Coast, CA
Posts: 3,207
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Great news, Christine! Not sure I've learned the patience thing yet...
__________________
Chris in Scotts Valley
June 2002 extensive hi grade DCIS (pre-cancer-stage 0, clean sentinal node) Mastectomy/implant - no chemo, rads. "cured?"
9/2004 Diag: Stage IV extensive liver mets (!) ER/PR- Her2+++
10/04-3/05 Weekly Taxol/Carboplatin/Herceptin , complete response!
04/05 - 4/07 Herception every 3 wks, Continue NED
04/07 - recurrence to liver - 2 spots, starting tykerb/avastin trial
06/07 8/07 10/07 Scans show stable, continue on Tykerb/Avastin
01/08 Progression in liver
02/08 Begin (TDM1) trial
08/08 NED! It's Working! Continue on TDM1
02/09 Continue NED
02/10 Continue NED. 5/10 9/10 Scans NED 10/10 Scans NED
12/10 Scans not clear....4/11 Scans suggest progression 6/11 progression confirmed in liver
07/11 - 11/11 Herceptin/Xeloda -not working:(
12/11 Begin MM302 Phase I trial - bust:(
03/12 3rd times the charm? AKT trial
5/12 Scan shows reduction! 7/12 More reduction!!!!
8/12 Whoops...progression...trying for Perjeta/Herceptin (plus some more nasty chemo!)
9/12 Start Perjeta/Herceptin, chemo on hold due to infection/wound in leg, added on cycle 2 &3
11/12 Poops! progression in liver, Stop Perjeta/Taxo/Herc
11/12 Navelbine/Herce[ptin - try for a 3 cycles, no go.
2/13 Gemzar/Carbo/Herceptin - no go.
3/13 TACE procedure
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11-07-2007, 05:58 PM
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#40
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Senior Member
Join Date: Jan 2007
Location: Thornhill, Ontario
Canada
Posts: 2,320
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Great news Christine. I am thrilled for you, Joe and your girls.
all the best
caya
__________________
ER90%+/PR 50%+/HER 2+
1.7 cm and 1.0 cm.
Stage 1, grade 2, Node Negative (16 nodes tested)
MRM Dec.18/06
3 x FEC, 3 x Taxotere
Herceptin - every 3 weeks for a year, finished May 8/08
Tamoxifen - 2 1/2 years
Femara - Jan. 1, 2010 - July 18, 2012
BRCA1/BRCA2 Negative
Dignosed 10/16/06, age 48 , premenopausal
Mild lymphedema diagnosed June 2009 - breast surgeon and lymph. therapist think it's completely reversible - hope so.
Reclast infusion January 2012
Oopherectomy October 2013
15 Years NED!!
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