Tamoxifen drug appears to kill fungus associated with deadly brain infection

[News]

The drug tamoxifen appears to kill a fungus associated with a deadly brain infection that afflicts HIV/AIDS patients, according to a University of Rochester study published online today by mBio, the journal of the American Society for Microbiology.

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['lizbeth]

Great! A good use for that Tamoxifen that Linn65 is no longer taking . . .

[donocco]

I read this in a pharmacy journal. Apparently it effects
a calcium dependent enzyme called Calmodulin. I wonder how well Tamoxifen gets into the brain as Crytococcosis is often a brain infection. For those who like trivia the yeast Crytococcus Neoformans is theonly yeast that never produces a mycelial mold like form. It only exists as a budding yeast cell


Paul