Go Back   HER2 Support Group Forums > Articles of Interest
Register Gallery FAQ Members List Calendar Search Today's Posts Mark Forums Read

Thread Tools Display Modes
Old 09-21-2010, 01:01 PM   #1
Senior Member
Join Date: Nov 2005
Posts: 240
Treating Cancer Based on Its Genome

Nguyen is offline   Reply With Quote
Old 09-21-2010, 04:15 PM   #2
Senior Member
Rich66's Avatar
Join Date: Feb 2008
Location: South East Wisconsin
Posts: 3,431
Re: Treating Cancer Based on Its Genome

In one of the first cases to apply the technology to clinical practice, scientists from the BC Cancer Center in Vancouver twice sequenced the genome of cancer cells in a patient with a very rare type of tumor--an adenocarcinoma of the tongue. They sequenced the DNA after the cancer had spread, and then again after it developed resistance to a drug.
Because the cancer is so rare, there were no standard courses of treatment for oncologists to choose from. So Steven Jones and collaborators used the genetic variations that they had identified, along with their knowledge of the molecular pathways that have been implicated in cancer, to create a model for what might be driving cancer in that patient. They narrowed in on a defect in a specific molecular pathway linked to cancer cell growth. The patient's physician then chose to treat him with a drug that inhibits that pathway, and the patient's tumor stopped growing for eight months. "A rare tumor is never going to have clinical trials," says Jones. "With diseases with no options, any level of information is appreciated."
.................................................. ....................

Mom's treatment history (link)
Rich66 is offline   Reply With Quote

Thread Tools
Display Modes

Posting Rules
You may not post new threads
You may not post replies
You may not post attachments
You may not edit your posts

BB code is On
Smilies are On
[IMG] code is On
HTML code is On

Forum Jump

All times are GMT -7. The time now is 12:15 PM.

Powered by vBulletin® Version 3.8.7
Copyright ©2000 - 2020, vBulletin Solutions, Inc.
Copyright HER2 Support Group 2007
free webpage hit counter