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Old 07-03-2011, 05:38 AM   #21
Jackie07
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Re: Vitamin D thread -Please use this for your Vit D info.

Newsmax also listed 6 reasons for getting adequate Vit. D:

http://www.newsmaxhealth.com/headlin...mo_code=C8A4-1
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3-11 Appendectomy - visually O.K., a lot of puss. Final path result - not cancer.
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10-10 Stopped Exemestane due to r. hip/l.thigh pain OKed by Onco 11-08-2016
7-23-2018 9 mm groundless(granules?) nodule within the right lower lobe with indolent behavior. Due to possible adenocarcinoma, Recommend annual surveilence.
7-10-2019 CT to check lung nodule.

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Old 08-29-2011, 09:30 PM
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Old 10-02-2011, 03:16 PM   #22
R.B.
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Re: Vitamin D thread -Please use this for your Vit D info.

Breast Cancer Res. 2011 Jul 26;13(4):R74. [Epub ahead of print]
Serum 25-hydroxyvitamin D and postmenopausal breast cancer survival: a prospective patient cohort study.
Vrieling A, Hein R, Abbas S, Schneeweiss A, Flesch-Janys D, Chang-Claude J.
Source

Division of Cancer Epidemiology, German Cancer Research Center, Im Neuenheimer Feld 581, 69120 Heidelberg, Germany. a.vrieling@dkfz-heidelberg.de.
Abstract

ABSTRACT:
INTRODUCTION:

Vitamin D has been postulated to be involved in cancer prognosis. Thus far, only two studies reported on its association with recurrence and survival after breast cancer diagnosis yielding inconsistent results. Therefore, the aim of our study was to assess the effect of post-diagnostic serum 25-hydroxyvitamin D [25(OH)D] concentrations on overall survival and distant disease-free survival.
METHODS:

We conducted a prospective cohort study in Germany including 1,295 incident postmenopausal breast cancer patients aged 50-74 years. Patients were diagnosed between 2002 and 2005 and median follow-up was 5.8 years. Cox proportional hazards models were stratified by age at diagnosis and season of blood collection and adjusted for other prognostic factors. Fractional polynomials were used to assess the true dose-response relation for 25(OH)D.
RESULTS:

Lower concentrations of 25(OH)D were linearly associated with higher risk of death (hazard ratio (HR) = 1.08 per 10 nmol/L decrement; 95% confidence interval (CI), 1.00 to 1.17) and significantly higher risk of distant recurrence (HR = 1.14 per 10 nmol/L decrement; 95%CI, 1.05 to 1.24). Compared with the highest tertile (≥ 55 nmol/L), patients within the lowest tertile (< 35 nmol/L) of 25(OH)D had a HR for overall survival of 1.55 (95%CI, 1.00 to 2.39) and a HR for distant disease-free survival of 2.09 (95%CI, 1.29 to 3.41). In addition, the association with overall survival was found to be statistically significant only for 25(OH)D levels of blood samples collected before start of chemotherapy but not for those of samples taken after start of chemotherapy (P for interaction = 0.06).
CONCLUSIONS:

In conclusion, lower serum 25(OH)D concentrations may be associated with poorer overall survival and distant disease-free survival in postmenopausal breast cancer patients.

PMID:
21791049
[PubMed - as supplied by publisher]
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Old 10-02-2011, 03:22 PM   #23
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Re: Vitamin D thread -Please use this for your Vit D info.

Serum 25-hydroxyvitamin D is inversely associated with body mass index in cancer
Pankaj G Vashi,1 Carolyn A Lammersfeld,1 Donald P Braun,1 and Digant Guptacorresponding author1
1Cancer Treatment Centers of America® (CTCA) at Midwestern Regional Medical Center, 2520 Elisha Avenue, Zion, IL, 60099, USA


http://www.ncbi.nlm.nih.gov/pmc/arti...4/?tool=pubmed

(Full Free Text)

"Conclusions
Obese cancer patients (BMI >= 30 kg/m2) had significantly lower levels of serum 25(OH)D as compared to non-obese patients (BMI <30 kg/m2). BMI should be taken into account when assessing a patient's vitamin D status and more aggressive vitamin D supplementation should be considered in obese cancer patients.


Background
Serum 25-hydroxyvitamin D [25(OH)D] is the major circulating form of vitamin D and a standard indicator of vitamin D status [1,2]. Several studies have described an inverse relationship between serum 25(OH)D and cancer risk [3-5]. The relationship between regular vitamin D intake and reduced cancer incidence has also been reported [6]. Furthermore, higher plasma 25(OH)D levels are associated with improved survival in prostate [7], breast [8], lung [9], colorectal [10] and ovarian [11] cancers. A better vitamin D status at the time of diagnosis and treatment, adjusted for season of diagnosis, has been shown to improve survival [12,13].
Several factors are involved in the regulation of 25(OH)D including: age; gender [14]; race [15]; dietary intake [2]; season [16]; and sunlight exposure [17]. Recently, the relationship between obesity and vitamin D status has been investigated suggesting decreased bioavailability of 25(OH)D from cutaneous and dietary sources in association with obesity [18]. "
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Old 10-02-2011, 03:25 PM   #24
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Re: Vitamin D thread -Please use this for your Vit D info.

Ann Surg Oncol. 2011 Jul;18(7):1830-6. Epub 2010 Dec 14.
Vitamin D deficiency is correlated with poor outcomes in patients with luminal-type breast cancer.
Kim HJ, Lee YM, Ko BS, Lee JW, Yu JH, Son BH, Gong GY, Kim SB, Ahn SH.
Source

Department of Surgery, Asan Medical Center, University of Ulsan, College of Medicine, Seoul, Korea.

(Full Free Text)

http://www.ncbi.nlm.nih.gov/pmc/arti...7/?tool=pubmed


Abstract
PURPOSE:

Vitamin D deficiency may be an indicator of poor prognosis in patients with breast cancer before surgery. We investigated the association between serum vitamin D concentration and breast cancer prognosis according to intrinsic cancer subtypes.
METHODS:

From June to December 2006, serum 25-OHD was measured in 310 Korean women with breast cancer who were treated at the Asan Medical Center, Korea. Clinicopathologic data were examined to determine the prognostic effects of serum 25-OHD. Expression of estrogen receptor (ER), progesterone receptor (PR), and epidermal growth factor receptor 2 (Her2) were measured using tissue microarrays. Patients were classified with luminal A, luminal B, Her2-enriched, or basal-like subtypes of breast cancer.
RESULTS:

Mean patient age was 48.7 years, and mean serum 25-OHD concentration was 31.4 ± 16.1 ng/ml. The 25-OHD levels were deficient (< 20 ng/ml) in 75 patients (24.2%), insufficient (20-29 ng/ml) in 95 (30.6%), and sufficient (30-150 ng/ml) in 140 (45.2%). Women with deficient 25-OHD levels were at increased risk of recurrence compared with those with sufficient vitamin D levels (P = 0.002). The 25-OHD concentration was inversely associated with prognosis of patients with cancer of the luminal A (P = 0.012) and luminal B subtypes (P =0.023), but not with the prognosis of patients with Her2/neu-enriched (P = 0.245) or triple-negative (P = 0.879) cancer subtypes. This association remained valid after adjustment for age, tumor size, nodal status, and estrogen receptor status (hazards ratio = 3.97; 95% confidence interval = 1.77-9.61).
CONCLUSIONS:

Vitamin D deficiency may be associated with poor outcomes in patients with luminal-type breast cancer.
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Old 11-03-2011, 08:51 AM   #25
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Re: Vitamin D thread -Please use this for your Vit D info.

I wouldn't disagree that sunlight is the "most natural" way to get vitamin D, however for many reasons people can become deficient (those who do not spend much time outside or live in high latitude climates, or have other conditions which may deplete vit D). So in some cases, people may benefit from supplementation - of course with the concurrence of their doctor.
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Old 11-03-2011, 03:57 PM   #26
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Re: Vitamin D thread -Please use this for your Vit D info.

75% of a group of early cancer sufferers were either vit d insufficient or plain deficient !, which is scary given the importance of vitamin D, and its wider involvement in cellular function than is generally realised


J Clin Oncol. 2009 Aug 10;27(23):3757-63. Epub 2009 May 18.
Prognostic effects of 25-hydroxyvitamin D levels in early breast cancer.
Goodwin PJ, Ennis M, Pritchard KI, Koo J, Hood N.
Source

Mount Sinai Hospital, 1284-600 University Ave, Toronto, Ontario M5G 1X4, Canada. pgoodwin@mtsinai.on.ca
Abstract
PURPOSE:

Vitamin D has been linked to breast cancer risk, but prognostic effects are unknown. Such effects are biologically plausible given the presence of vitamin D receptors in breast cancer cells, which act as nuclear transcription factors to regulate gene activity.
PATIENTS AND METHODS:

The study was conducted in a prospective inception cohort of 512 women with early breast cancer diagnosed 1989 to 1996. Vitamin D levels were measured in stored blood. Clinical, pathologic, and dietary data were accessed to examine prognostic effects of vitamin D.
RESULTS:

Mean age was 50.4 years, mean vitamin D was 58.1 +/- 23.4 nmol/L. Vitamin D levels were deficient (< 50 nmol/L) in 37.5% of patients, insufficient (50 to 72 nmol/L) in 38.5% of patients, and sufficient (> 72 nmol/L) in 24.0% of patients. There was little variation in mean vitamin D levels between summer and winter months. Mean follow-up was 11.6 years; 116 women had distant recurrences, and 106 women died. Women with deficient vitamin D levels had an increased risk of distant recurrence (hazard ratio [HR] = 1.94; 95% CI, 1.16 to 3.25) and death (HR = 1.73; 95% CI, 1.05 to 2.86) compared with those with sufficient levels. The association remained after individual adjustment for key tumor and treatment related factors but was attenuated in multivariate analyses (HR = 1.71; 95% CI, 1.02 to 2.86 for distant recurrence; HR = 1.60; 95% CI, 0.96 to 2.64 for death).

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Old 01-15-2012, 05:19 AM   #27
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Re: Vitamin D thread -Please use this for your Vit D info.

An interview with Dr Michael Holick a leading light and source of important original research into vitamin D. which includes discussion on breast cancer


I have mixed views about the paleo diet as often portrayed, and some of the opinions expressed in interviews on this site, but Holick is a leading researcher into vitamin D.


http://www.thelivinlowcarbshow.com/s...t-episode-443/


You can also find a truly excellent video lecture at UCLA by him here as mentioned below which I would recommend you watch before listening to the interview.


http://www.uctv.tv/search-details.aspx?showID=15773

Last edited by R.B.; 02-05-2013 at 03:09 PM..
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Old 01-15-2012, 01:35 PM   #28
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Thumbs up Re: Vitamin D thread -Please use this for your Vit D info.

Thank you so much, RB, for never forgetting us, and keeping us aware of the basis for some of the things we can do that are not difficult to help ourselves.

AlaskaAngel
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Old 01-15-2012, 04:29 PM   #29
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Re: Vitamin D thread -Please use this for your Vit D info.

^ Thanks for your kind words - you are very welcome AA.

I have just found this a passionate understandable very punchy lecture to doctors by Dr Holick.

(-: A MUST WATCH (-:


Pass it on please (-:


http://www.uctv.tv/search-details.aspx?showID=15773

Last edited by R.B.; 07-03-2012 at 01:53 PM..
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Old 03-28-2012, 05:08 AM   #30
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Re: Vitamin D thread -Please use this for your Vit D info.

It is a better post and it is fantastic thing to look at and thanks for sharing.
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Old 03-28-2012, 08:04 AM   #31
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Re: Vitamin D thread -Please use this for your Vit D info.

R.B.

That UCTV link by Dr. Holick is wonderful. Thank you.
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3 Infertility tmts 99 > 3 u. fibroids > Pills
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Recc IIB 2.5 cm Bi-L Mast 61407 2/9 nds PET
6 TCH Cellulitis - Lymphedema - compression sleeve & glove
H w x 4 MUGA 51 D, J 49 M
Diastasis recti
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hptc hemangioma
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hysterectomy/oophorectomy 011410
Exemestane 25 mg tab 102912 ~ 101016 stopped due to r. hip/l.thigh pain after long walk
DEXA 1/13
1-2016 lesions in liver largest 9mm & 1.3 cm onco. says not cancer.
3-11 Appendectomy - visually O.K., a lot of puss. Final path result - not cancer.
Start Vitamin D3 and Calcium supplement (600mg x2)
10-10 Stopped Exemestane due to r. hip/l.thigh pain OKed by Onco 11-08-2016
7-23-2018 9 mm groundless(granules?) nodule within the right lower lobe with indolent behavior. Due to possible adenocarcinoma, Recommend annual surveilence.
7-10-2019 CT to check lung nodule.

"I WANT TO BE AN OUTRAGEOUS OLD WOMAN WHO NEVER GETS CALLED AN OLD LADY. I WANT TO GET SHARP EDGED & EARTH COLORED, TILL I FADE AWAY FROM PURE JOY." Irene from Tampa

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Old 06-12-2012, 03:48 AM   #32
R.B.
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Re: Vitamin D thread -Please use this for your Vit D info.

If you found the Holick lecture above interesting you may also like this paper. It is a bit technical but if you ignore the bits that are complex you will get the gist that greater sun exposure may = lower risk of a range of cancers, that most if not all tissues use and can make the active form of vitamin D from the vitamin D precursor made by the action of sunlight in the skin, and that it appears that Vit D helps regulate cell division.



Vitamin D: Its role in cancer prevention and treatment
Michael F. Holick

Prog Biophys Mol Biol. 2006 Sep;92(1):49-59. Epub 2006 Mar 10.
Vitamin D: its role in cancer prevention and treatment.
Holick MF.
Source

Boston University Medical Center, 715 Albany Street, M-1013, Boston, MA 02118, USA. mfholick@bu.edu
Abstract

Vitamin D, the sunshine vitamin, has been recognized for almost 100 years as being essential for bone health. Vitamin D provides an adequate amount of calcium and phosphorus for the normal development and mineralization of a healthy skeleton. Vitamin D made in the skin or ingested in the diet, however, is biologically inactive and requires obligate hydroxylations first in the liver to 25-hydroxyvitamin D, and then in the kidney to 1,25-dihydroxyvitamin D. 25-Hydroxyvitamin D is the major circulating form of vitamin D that is the best indicator of vitamin D status. 1,25-dihydroxyvitamin D is the biologically active form of vitamin D. This lipid-soluble hormone interacts with its specific nuclear receptor in the intestine and bone to regulate calcium metabolism. It is now recognized that the vitamin D receptor is also present in most tissues and cells in the body. 1,25-dihydroxyvitamin D, by interacting with its receptor in non-calcemic tissues, is able to elicit a wide variety of biologic responses. 1,25-dihydroxyvitamin D regulates cellular growth and influences the modulation of the immune system. There is compelling epidemiologic observations that suggest that living at higher latitudes is associated with increased risk of many common deadly cancers. Both prospective and retrospective studies help support the concept that it is vitamin D deficiency that is the driving force for increased risk of common cancers in people living at higher latitudes. Most tissues and cells not only have a vitamin D receptor, but also have the ability to make 1,25-dihydroxyvitamin D. It has been suggested that increasing vitamin D intake or sun exposure increases circulating concentrations of 25-hydroxyvitamin D, which in turn, is metabolized to 1,25-dihydroxyvitamin D(3) in prostate, colon, breast, etc. The local cellular production of 1,25-dihydroxyvitamin D acts in an autocrine fashion to regulate cell growth and decrease the risk of the cells becoming malignant. Therefore, measurement of 25-hydroxyvitamin D is important not only to monitor vitamin D status for bone health, but also for cancer prevention.

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Old 02-05-2013, 03:14 PM   #33
R.B.
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Re: Vitamin D thread -Please use this for your Vit D info.

http://www.ncbi.nlm.nih.gov/pubmed/23237739

Is prevention of cancer by sun exposure more than just the effect of vitamin D? A systematic review of epidemiological studies.
van der Rhee H, Coebergh JW, de Vries E.
Source

Department of Dermatology, Hagaziekenhuis, P.O. Box 40551, Leyweg 275, 2504 LN Den Haag, Zuid-Holland, The Netherlands. Electronic address: hvdrhee@casema.nl.
Abstract

The number of studies reporting on the association between sunlight exposure, vitamin D and cancer risk is steadily increasing. We reviewed all published case-control and cohort studies concerning colorectal-, prostate-, breast cancer, non-Hodgkin's lymphoma (NHL) and both sunlight and vitamin D to update our previous review and to verify if the epidemiological evidence is in line with the hypothesis that the possible preventive effect of sunlight on cancer might be mediated not only by vitamin D but also by other pathways. We found that almost all epidemiological studies suggest that chronic (not intermittent) sun exposure is associated with a reduced risk of colorectal-, breast-, prostate cancer and NHL. In colorectal- and to a lesser degree in breast cancer vitamin D levels were found to be inversely associated with cancer risk. In prostate cancer and NHL, however, no associations were found. These findings are discussed and it is concluded that the evidence that sunlight is a protective factor for colorectal-, prostate-, breast cancer and non-Hodgkin's lymphoma is still accumulating. The same conclusion can be drawn concerning high vitamin D levels and the risk of colorectal cancer and possibly breast cancer. Particularly in prostate cancer and NHL other sunlight potentiated and vitamin D independent pathways, such as modulation of the immune system and the circadian rhythm, and the degradation of folic acid might play a role in reduced cancer risk as well.
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Old 02-06-2013, 07:22 AM   #34
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Re: Vitamin D thread -Please use this for your Vit D info.

Vitamin D and the mammary gland: a review on its role in normal development and breast cancer

http://breast-cancer-research.com/content/14/3/211

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Old 02-06-2013, 10:25 AM   #35
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Re: Vitamin D thread -Please use this for your Vit D info.

Thanks Hopeful - great article (=:

Here is a study suggesting vitamin D may have a particular relevance in ER (estrogen receptor) based cancers.


http://www.biomedcentral.com/1471-2407/10/483

Alterations in Vitamin D signalling and metabolic pathways in breast cancer progression: a study of VDR, CYP27B1 and CYP24A1 expression in benign and malignant breast lesions Vitamin D pathways unbalanced in breast lesions

Nair Lopes1, Bárbara Sousa1, Diana Martins1, Madalena Gomes1, Daniella Vieira2, Luiz A Veronese3, Fernanda Milanezi1, Joana Paredes1, José L Costa1 and Fernando Schmitt1,4*

Conclusions

From this study, we conclude that there is a deregulation of the Vitamin D signalling and metabolic pathways in breast cancer, favouring tumour progression. Thus, during mammary malignant transformation, tumour cells lose their ability to synthesize the active form of Vitamin D and respond to VDR-mediated Vitamin D effects, while increasing their ability to degrade this hormone.


Paragraph re ER cancers


Vitamin D receptor (VDR)

"An interesting finding is the correlation between the expression of the VDR and the ER in both in situ and invasive carcinomas. In fact, the VDR is expressed in most ER-positive cases (54.7% in in situ carcinomas and 65.5% in invasive tumours). It is thought that one of the VDR functions is to counteract oestrogen-mediated proliferation and maintain differentiation [12]. Indeed, data support the concept that the anti-tumour effects of Vitamin D and its analogues on ER-positive human breast cancer cells are mediated through the down regulation of the ER itself and the attenuation of oestrogen responses, such as breast cancer cell growth [29,30]. Thus, being the VDR mostly expressed in ER-positive carcinomas, Vitamin D or its analogues may become an alternative therapy for these tumours in cases of resistance to ER-targeted therapy. "

Last edited by R.B.; 02-06-2013 at 11:05 AM..
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Old 02-06-2013, 11:02 AM   #36
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Re: Vitamin D thread -Please use this for your Vit D info.

A trial looking at a vitamin D analogue and HER2 cancers and showing positive outcomes.

Above it appears that vitamin D is relevant to estrogen positive cancers, and below an analogue shows promise in a estrogen negative HER2 positive cancer . . .

Sadly they do not report / nobody appears to have looked at natural Vitamin D and HER2, probably as usual because there is no money to be made, and if they did find it works effectively it would reduce any interest in analogues . . .


Situation 'Human condition' normal . . . )-:



http://www.ncbi.nlm.nih.gov/pmc/articles/PMC2906695/

Gemini Vitamin D Analog Suppresses ErbB2-Positive Mammary Tumor Growth via Inhibition of ErbB2/AKT/ERK Signaling
Hong Jin Lee,1 Jae-Young So,1 Andrew DeCastro,1 Amanda Smolarek,1 Shiby Paul,1 Hubert Maehr,1 Milan Uskokovic,1 and Nanjoo Suh1,2


Numerous synthetic vitamin D analogs have been studied for their effects on the prevention and treatment of breast cancer. However, the inhibitory effects of naturally occurring 1α,25-dihydroxyvitamin D3 or its synthetic analogs on ErbB2 overexpressing mammary tumorigenesis have not been reported. Gemini vitamin D analogs are novel synthetic vitamin D derivatives with a unique structure of two six-carbon chains at C-20. We have previously shown that Gemini vitamin D analogs significantly inhibited carcinogen-induced estrogen receptor (ER)-positive mammary tumorigenesis and reduced ER-negative MCF10DCIS.com xenograft tumor growth without hypercalcemic toxicity. In the present study, we have determined the inhibitory effect of a potent Gemini vitamin D analog BXL0124 (1α,25-dihydroxy-20R-21(3-hydroxy-3-deuteromethyl-4,4,4-trideuterobutyl)-23-yne-26,27-hexafluoro-cholecalciferol) on the ErbB2/Her-2/neu overexpressing mammary tumorigenesis. The Gemini BXL0124 inhibits ErbB2-positive mammary tumor growth and down-regulates the phosphorylation of ErbB2, ERK and AKT in tumors of MMTV-ErbB2/neu transgenic mice. These effects of Gemini BXL0124 in vivo were confirmed by using the ErbB2 overexpressing tumor cells derived from the mammary tumors of MMTV-ErbB2/neu mice. In conclusion, the Gemini vitamin D analog BXL0124 inhibits the growth of ErbB2 overexpressing mammary tumors through regulating the ErbB2/AKT/ERK signaling pathways, suggesting that Gemini vitamin D analog may be considered for translational studies.


And from the body of the text


"In conclusion, the Gemini vitamin D analog BXL0124 inhibits ER-negative/ErbB2 positive mammary tumorigenesis without hypercalcemic toxicity via regulating ErbB2/ErbB3-driven downstream signaling, ERK, AKT and cell cycle regulator, cyclin D1. Taken together with our previous study [10], Gemini vitamin D analogs, especially BXL0124, may be potent agents in the prevention of different types of human breast cancer without toxicity, and should be considered for translational studies."

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Old 07-15-2013, 04:35 PM   #37
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Re: Vitamin D thread -Please use this for your Vit D info.

Thank you so much for all the posts here on vitamin D. It looks like all of the studies have shown that a low vitamin D level is associated with poorer outcomes for cancer patient. Is it possible that the vitamin D levels are low because these patients have more aggressive cancers which "use up" the vitamin D. In other words, is the low vitamin D a result of the worse cancer or does it increase the risk of more cancer? I guess the only way to know for sure would be to do a randomnized study of cancer patients where half the patients received vitamin D and the other half a placebo. Is anyone aware of a study like that?
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Old 07-15-2013, 04:45 PM   #38
bmorr7
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Re: Vitamin D thread -Please use this for your Vit D info.

Hi

I just found a randomnized study showing that taking vitamin D lowers the risk of cancers (although the number of cancers in the study was relatively low).

http://ajcn.nutrition.org/content/85....full.pdf+html
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Old 08-07-2013, 02:20 PM   #39
R.B.
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Re: Vitamin D thread -Please use this for your Vit D info.

Does cancer increase the metabolism of vitamin D - good question ! I have no idea; but from observations in this paper indeed it might, or at least significantly so when cancer has spread to regional areas, which raises interesting questions.

It appears much is still not known, and sufficient research has still not been done, presumably in part because there is limited funding for research into treatments that cannot be patented.

(I have only just found this paper as a result of your question, and only skimmed it - I will read it more fully at a later point)


http://www.ncbi.nlm.nih.gov/pmc/articles/PMC3600307/

says in the introduction

"Numerous observational studies have reported an inverse association between vitamin D status, including circulating 25-hydroxyvitamin D (25(OH)D) levels, and breast cancer risk. "

and concludes


"In spite of the substantial literature on the topic of vitamin D and breast cancer risk and survival, future studies need to focus on gaining a better understanding of the biologic effects of vitamin D in breast tissue. If the antitumor effects of vitamin D are confirmed in human studies, then a more accurate dosage of vitamin D for both prophylactic and therapeutic purposes needs to be established. Based upon the current literature, the Institute of Medicine (IOM) concluded that for cancer and vitamin D, the evidence was “inconsistent and insufficient to inform nutritional requirements” [11]. Therefore, the benefits of routine monitoring of serum 25(OH)D and vitamin D supplementation for breast cancer prevention or to reduce recurrence among breast cancer survivors are uncertain. Given the high prevalence of vitamin D deficiency among high-risk women and breast cancer survivors [84, 170, 239] and the relatively low toxicity and low cost of supplementation, vitamin D is a potentially modifiable risk factor to target as a strategy for breast cancer prevention and treatment."


There does seem to be quite a lot of interest in the topic which is hopeful viz an ACS article which contains some useful information.

http://www.cancer.org/treatment/trea...rals/vitamin-d

Last edited by R.B.; 08-07-2013 at 02:31 PM..
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Old 08-07-2013, 02:36 PM   #40
R.B.
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Re: Vitamin D thread -Please use this for your Vit D info.

I also have just found this research based video, which is authoritative understandable and fascinating

In the MUST WATCH category (-:




http://www.youtube.com/watch?v=CAtsKU-FmvU

Last edited by R.B.; 08-07-2013 at 03:45 PM..
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