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Old 06-28-2008, 05:44 AM   #1
dhealey
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Join Date: Jun 2007
Location: moved to Lancaster, Pa in June, 2010
Posts: 576
trial for breast cancer vaccine
Anyone on the boards ever participate in a trial for the breast cancer vaccine? Wake Forest Baptist Hospital in Winston Salem, NC is starting a trial for this, you have to be her2 positive and have finished treatment 6 months ago. I have contacted them and I am trying to get into this trial. Could use any feedback on anyone who has participated.
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Debbie in North Carolina
Diag 10/2006-high grade invasive ductal carcinoma- mastectomy L breast
2.5 cm tumor ER/PR pos-Her2+++
4 rounds A/C, 4 rounds Taxol
Herceptin every 3 weeks until Jan. 2008
6/18/07 prophylatic mastectomy R breast
8/2007 started aromasin/stopped arimidex (side effects)
12/07 stopped aromasin due to side effects (now what?)
Finished herceptin 1/8/08
started tamoxifen for 2 years then will switch to femera
allergic to tamoxifen started femera 4/2008
June 20, 2008 portacath removed
Learnig to live life to the fullest!
Stopped Femera due to side effects
July 28, 2008 start trial for breast cancer vaccine
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Old 06-28-2008, 09:36 AM   #2
Janelle
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Join Date: Nov 2007
Location: Brentwood, CA
Posts: 76
I have heard of this trial (I think it is a phase 3 trial the E75 vaccine). I also think you may get randomized to the non-vaccine arm. Just an FYI....
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Janelle
Diagnosed October 2006 at age 37 wtih grade 3 IDC and high grade DCIS
Stage 1c triple positive, no node involvement but
vascular invasion
multifocal disease
Lumpectomy November, 2006
A/C every 3 weeks (started Jan., 2007 and finished March 2007); followed weekly Taxol (finished June 2007) concurrent with Herceptin (finished March 2008);
Bilateral Mast with immediate recon in Sept 2007; finished recon Dec. 2007
Started 5 years of tamoxifen Nov. 2007; started peptide vaccine clinical trial at MD Anderson October 2008 and finished active part of trial in April 2009 (monthly injections of AE37 peptitde (HLA type specific) with GM-CSF or GM-CSF alone depending on if I was in experimental or control group); started Zometa infusions June 25, 2009- 4mg every 6 months for 3 years (taking it "off-label" to try to prevent mets)
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Old 06-28-2008, 10:54 AM   #3
Julie2
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Join Date: Sep 2005
Posts: 556
Dhealy,

Do you have any link to this trial? Is this Leukocyte Infusion Therapy (LIFT)trial?

Thanks,
Julie
__________________
Diagnosed in Sept 2004 while pregnant with the second child. Stage 3b, tumor 4.5cm, 4 auxillary and supraclav node positive. Her2+++ FISH 9.4 and er-,pr-.
Had dose dense neoadjuvant AC,Taxol then mastectomy,radiation+xeloda+Herceptin.
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Old 06-28-2008, 01:41 PM   #4
dhealey
Senior Member
 
Join Date: Jun 2007
Location: moved to Lancaster, Pa in June, 2010
Posts: 576
Julie , I don't have any links to this trial. I found out about it through the doctor I work for and our local news did a story on it. I called the number they gave out and am awaiting a call back. I do meet the critira for the trial though. Apparently they are looking for 100 participants. You must be her2 positive, high risk, and finished treatment 6 months ago. I will post more as I get more info. Apparently they will give you 6 injections of the vaccine over a 18 month period.
__________________
Debbie in North Carolina
Diag 10/2006-high grade invasive ductal carcinoma- mastectomy L breast
2.5 cm tumor ER/PR pos-Her2+++
4 rounds A/C, 4 rounds Taxol
Herceptin every 3 weeks until Jan. 2008
6/18/07 prophylatic mastectomy R breast
8/2007 started aromasin/stopped arimidex (side effects)
12/07 stopped aromasin due to side effects (now what?)
Finished herceptin 1/8/08
started tamoxifen for 2 years then will switch to femera
allergic to tamoxifen started femera 4/2008
June 20, 2008 portacath removed
Learnig to live life to the fullest!
Stopped Femera due to side effects
July 28, 2008 start trial for breast cancer vaccine
dhealey is offline   Reply With Quote
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