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Old 05-26-2009, 09:01 AM   #1
donalddonald
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promising drug regimen for slowing growth of breast cancer
Is this news new? How about Tykerb combo with vinorelbine and capecitabine?

...............The trial mixed two chemotherapy drugs, called capecitabine and vinorelbine, and a drug called Herceptin, used to treat patients whose breast cancer is the aggressive HER2-positive form.............

http://www.jacksonville.com/news/met...slowing_growth
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My wife:
03/06 First diagnosed at age 33
04/06 resected ER/PR- Her2 +3
05/06 AC + TH followed Herceptin full 1 year
03/08 Right lung mets
04/08 resected
05/08 Xeloda + Tykerb (500 mg)
10/08 Brain mets
1 big (4 cm) and 3 small (1 CM)
02/09 Brain radiation
03/09 left lung spots found
04/09 Vinorelbine + Tykerb (1250 mg)
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Old 05-26-2009, 12:17 PM   #2
Sheila
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Location: Morris, IL
Posts: 3,507
DonaldDonald
Thanks for this...i had just read something about this treatment combo, and since I have had Xeloda, and am now on Navelbine, i will ask if they can add the Xeloda back in with the herceptin...the trippe decker so to speak...
'
I have heard Dr Edith Perez speak many times at San Antonio and she is amazing.
Thanks For this info!!!!
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Sheila
Diagnosed at age 49.99999 2/21/2002 via Mammography (Calcifications)
Core Biopsy 2/22/02
L. Mastectomy 2/25/2002
Stage 1, 0.7cm IDC, Node Neg from 19 nodes Her2+++ ER PR Neg
6/2003 Reconstruction W/ Tissue Expander, Silicone Implant
9/2003 Stage IV with Mets to Supraclavicular nodes
9/2003 Began Herceptin every 3 weeks
3/2006 Xeloda 2500mg/Herceptin for recurrence to neck nodes
3/2007 Added back the Xeloda with Herceptin for continued mets to nodes
5/2007 Taken Off Xeloda, no longer working
6/14/07 Taxol/Herceptin/Avastin
3/26 - 5/28/08 Taxol Holiday Whopeeeeeeeee
5/29 2008 Back on Taxol w Herceptin q 2 weeks
4/2009 Progression on Taxol & Paralyzed L Vocal Cord from Nodes Pressing on Nerve
5/2009 Begin Rx with Navelbine/Herceptin
11/09 Progression on Navelbine
Fought for and started Tykerb/Herceptin...nodes are melting!!!!!
2/2010 Back to Avastin/Herceptin
5/2010 Switched to Metronomic Chemo with Herceptin...Cytoxan and Methotrexate
Pericardial Window Surgery to Drain Pericardial Effusion
7/2010 Back to walking a mile a day...YEAH!!!!
9/2010 Nodes are back with a vengence in neck
Qualified for TDM-1 EAP
10/6/10 Begin my miracle drug, TDM-1
Mixed response, shrinking internal nodes, progression skin mets after 3 treatments
12/6/10 Started Halaven (Eribulen) /Herceptin excellent results in 2 treatments
2/2011 I CELEBRATE my 9 YEAR MARK!!!!!!!!!!!!!
7/5/11 begin Gemzar /Herceptin for node progression
2/8/2012 Gemzar stopped, Continue Herceptin
2/20/2012 Begin Tomo Radiation to Neck Nodes
2/21/2012 I CELEBRATE 10 YEARS
5/12/2012 BeganTaxotere/ Herceptin is my next miracle for new node progression
6/28/12 Stopped Taxotere due to pregression, Started Perjeta/Herceptin
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