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Re: Still riding my unicorn
Hello beautiful ladies,
Yes the trial are tablets like tykeb and it targets same epitope as tykerb but block them in a different ways, apparently 6 times stronger.
I so wish I could have it with herceptin (and a pi3k inhibitor) as I can imagine it would work even better..but I am a lab rat..
its in phase 1b at the moment only in UK (london) and Japan (where the company is from) I think they wanted a foothold in Europe wich is why they opened a trial centre here. I was the last breast cancer allowed to be enrolled in that phase 1 as they are also trialling it on other her2 or egfr positive cancer such as oesophagal cancer(some have very limited other treatment). Another lady with BC got a 29% reduction news last week at the trial centre.
Side effect are a bit more than tykerb i would say and I had a couple of rough weeks, but nothing compared to chemo. I have to say my skin went quite dry (I naturally have a good soft skin). That said the side effect have subsided in the past week.
I have also to say that I am worried as I can feel something in my throat again and I do not feel as energetic as I did few weeks ago: tight back & breathing less well.. so i am worried that things are growing again. I am thinking that they had reduced more before but are now growing again. So i find it hard to be celebrating fully but I will keep you posted, the next few weeks should let me know if things are kept at bay and hopefully I will feel as I did in January shortly again, I hope I hope go unicorn, go
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35 y/o
June 06: BC stage I
Grade 3; ER/PR neg
Her-2+++; lumpectomies
Aug 06: Stage IV
liver mets: 6 tumours
July 06 to Jan 07: 2*FEC+6*Taxotere; 3*TACE; LITT
March 07- Sept 07: Vaccination trial (phase 2, peptide based) at the UW (Seattle).
Herceptin since 2006
NED til Oct 09
Recurrence Oct 2009: to internal mammary gland since October 2009 missed on Oct and March 2010 scan.. palpable nodes in May 2010 when I realised..
Nov 2011:7 mets to lungs progressing fast failed hercp/tykerb/xeloda combo..
superior vena cava blocked: stent but face remains puffy
April 2012: Teresa Trial, randomised to TDM1
Nov 2012 progressing on TDM1
Dec 2012 blockage of my airways by tumours, obliteration of these blocking tumours breathing better but hoping for more- at mo too many tumours to count in the lungs and nodes.
Dec 2012 Starting new trial S-222611 phase 1b dual egfr her2+ inhibitor.
'Under no circumstances should you lose hope..' Dalai Lama
Last edited by fullofbeans; 02-10-2013 at 04:45 PM..
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Hybrid Mode
