HonCode

Go Back   HER2 Support Group Forums > her2group
Register Gallery FAQ Members List Calendar Today's Posts

Reply
 
Thread Tools Display Modes
Old 08-15-2007, 10:03 PM   #1
weezie1053
Senior Member
 
weezie1053's Avatar
 
Join Date: Nov 2006
Location: Bedford, Virginia
Posts: 134
Question Itching?? Side Affect to What?

Okay, I am almost too embarrassed to raise this question, but here goes. I I have been on Lyrica for the neuropathy for about 3 weeks. About 10 days ago, I started itching like a monkey infested with fleas. I have no visible rash. I itch mostly on my stomach. I asked my Onc about it, and he told me to stop taking Lyrica. The Lyrica was really relieving my neuropathy so I stayed on it another week. I even tried the Benandyrl. My Podiatrist, who prescribed the Lyrica, said he has only had two patients that had any side affect to the Lyrica. This weekend, I stopped because the itching is overwhelming. The Onc said Herceptin does not cause itching. I have looked up the symptons on Mayoclinic.com, and I do not have any jaundice--just itching. I'm a textbook for side affects so I thought I'd throw this one out there. Coincidentally, I have my first appointment with a dermatologist next Friday when I have my Herceptin and see my Onc. Although I have been off the Lyrica several days, I still itch so I am wondering if it is coming from something else.

Louise
__________________
  • Diagnosis 06/06 - Stage II-A BC; BC was 2.5 cm, grade 2; ER/PR negative & HER-2/neu positive;
  • Mastectomy w/ reconstruction (implant) in 09/06;lymph nodes - negative;
  • AC/Cytoxin combo - 4 treatments (dose dense);
  • Taxol/Herceptin combo- 12 weekly treatments;
  • Completed chemo - 2/07; completed restruction 02/07; reduction of left breast.
  • BRCA 1 and 2 negative - 6/15/07;DX high risk for distant recurrence
  • MRI, 08/02/07 - NED
  • 1 year Anniversary - 09/07; completed Herceptin 11/07.
  • Mammo 02/14/08 - NED; MRI - 08/2008 - NED
  • 2 year Anniversary - 09/08
  • Mammo 02/09 - NED; MRI - 08/09 - NED
  • 3rd year Anniversary - 09/09
  • 5th Annivery - 09/2011 - NED
weezie1053 is offline   Reply With Quote
Old 08-15-2007, 10:26 PM   #2
VaMoonRise
Deceased
 
Join Date: Mar 2006
Location: Virginia
Posts: 113
Hi Louise,

I am so sorry that you are itching like mad. I have no idea what could be causing it but I can relate. I have liver mets and brain mets. I recently went through WBR and my liver function is very high right now, I am Jaundiced. I just started on Xeloda and stopped Herceptin and I am being weaned off of a steroid. My skin feels like it is being stretched and itches like crazy at times, I too have no rash, much like a pregnant woman would feel as her skin stretches to make way for the baby. My feet and hands have started to itch too, not sure if the feet & hands are due to the Xeloda or not but I think the rest of my body that itches is due to being dehydrated. I am constantly drinking water, I never am without a bottle in my hand but I know that I am not drinking as much as I was since coming off of the steroid. Are you getting enough to drink? Just a thought. When was the last time you had any scans done or a tumor marker test?

I have found that putting a lot of lotion on does help to relieve my itching some.
Let me know what the Onc & dermatologist have to say. Hopefully they can figure out what is causing it and have a plan to give you some relief from it. I will keep you in my prayers that they do.

Love, Hugs & Good Vibes for Itching Relief,
Nicola
__________________



March 18, 2004, Age 36
Diagnosed: High Grade DCIS, Microcalcifications, Solid and Comedo type, Nuclear grade 3 with 1mm margins, ER+, PR+, Stage "0"
3-8-04 Left breast lumpectomy.
4-1-04 thru 6-24-04 Adjuvant XRT.
11-29-05 Gallbladder attack.
12-01-05 Surgery to have gallbladder removed, discovered cancer spread throughout liver in both lobes, HER2+ amplified by FISH and interestingly enough negative for ER and PR.
12-9-05 Clinical trial consisting of Tykerb, Taxol and Herceptin along with Zometa once a month. On clinical trial for 15 months before liver mets started progressing. Started on Navelbine 3-9-07. Navelbine failed, switched to Gemzar July 07. MRI of the brain on July 7, 07. Results revealed multiple brain tumors. Taken off of Gemzar immediately and began 15 rounds of WBR which I completed on July 26, 07. CT scan on 7-26-07 significant progression in the liver mets. I am now getting ready to start on Xeloda along with Herceptin and Zometa once a month.
VaMoonRise is offline   Reply With Quote
Old 08-16-2007, 11:45 AM   #3
hutchibk
Senior Member
 
hutchibk's Avatar
 
Join Date: Oct 2005
Posts: 3,519
Don't know if this helps at all, but I googled 'itching' and this is what I found...

What causes an itch? Itch accompanies many conditions. Probably the most common cause of itch is psychological, that is, due to stress, anxiety, etc. Stress also can aggravate itch from other causes. Dry skin is another frequent cause of itch. Many people also report sunburn itch following prolonged exposure to UV radiation from the sun. Other causes include metabolic and endocrine disorders (e.g., liver or kidney disease, hyperthyroidism), cancers (e.g., lymphoma), reactions to drugs, , and diseases of the blood (e.g., polycythemia vera).
Infections and infestations of the skin are another cause of itch. Common infectious causes of itch include a fungal infection of the crotch (tinea cruris) commonly known as jock itch as well as vaginal itching and/or anal itching from sexually-transmitted diseases (STDs) or other types of infections. Another type of parasitic infection resulting in itch is the so-called swimmer’s itch. Swimmer's itch, also called cercarial dermatitis, is a skin rash caused by an allergic reaction to infection with certain parasites of birds and mammals that are released from infected snails who swim in fresh and salt water. Itch may also result from skin infestation by body lice, including pubic lice. Most people who itch, however, do not have a serious underlying condition.
__________________
Brenda

NOV 2012 - 9 yr anniversary
JULY 2012 - 7 yr anniversary stage IV (of 50...)

Nov'03~ dX stage 2B
Dec'03~
Rt side mastectomy, Her2+, ER/PR+, 10 nodes out, one node positive
Jan'04~
Taxotere/Adria/Cytoxan x 6, NED, no Rads, Tamox. 1 year, Arimadex 3 mo., NED 14 mo.
Sept'05~
micro mets lungs/chest nodes/underarm node, Switched to Aromasin, T/C/H x 7, NED 6 months - Herceptin only
Aug'06~
micro mets chest nodes, & bone spot @ C3 neck, Added Taxol to Herceptin
Feb'07~ Genetic testing, BRCA 1&2 neg

Apr'07~
MRI - two 9mm brain mets & 5 punctates, new left chest met, & small increase of bone spot C3 neck, Stopped Aromasin
May'07~
Started Tykerb/Xeloda, no WBR for now
June'07~
MRI - stable brain mets, no new mets, 9mm spots less enhanced, CA15.3 down 45.5 to 9.3 in 10 wks, Ty/Xel working magic!
Aug'07~
MRI - brain mets shrunk half, NO NEW BRAIN METS!!, TMs stable @ 9.2
Oct'07~
PET/CT & MRI show NED
Apr'08~
scans still show NED in the head, small bone spot on right iliac crest (rear pelvic bone)
Sept'08~
MRI shows activity in brain mets, completed 5 fractions/5 consecutive days of IMRT to zap the pesky buggers
Oct'08~
dropped Xeloda, switched to tri-weekly Herceptin in combo with Tykerb, extend to tri-monthly Zometa infusion
Dec'08~
Brain MRI- 4 spots reduced to punctate size, large spot shrunk by 3mm, CT of torso clear/pelvis spot stable
June'09~
new 3-4mm left cerrebellar spot zapped with IMRT targeted rads
Sept'09~
new 6mm & 1 cm spots in pituitary/optic chiasm area. Rx= 25 days of 3D conformal fractionated targeted IMRT to the tumors.
Oct'09~
25 days of low dose 3D conformal fractionated targeted IMRT to the bone mets spot on rt. iliac crest that have been watching for 2 years. Added daily Aromasin back into treatment regimen.
Apr'10~ Brain MRI clear! But, see new small spot on adrenal gland. Change from Aromasin back to Tamoxifen.
June'10~ Tumor markers (CA15.3) dropped from 37 to 23 after one month on Tamoxifen. Continue to monitor adrenal gland spot. Remain on Tykerb/Herceptin/Tamoxifen.
Nov'10~ Radiate positive mediastinal node that was pressing on recurrent laryngeal nerve, causing paralyzed larynx and a funny voice.
Jan'11~ MRI shows possible activity or perhaps just scar tissue/necrotic increase on 3 previously treated brain spots and a pituitary spot. 5 days of IMRT on 4 spots.
Feb'11~ Enrolled in T-DM1 EAP in Denver, first treatment March 25, 2011.
Mar'11~ Finally started T-DM1 EAP in Denver at Rocky Mountain Cancer Center/Rose on Mar. 25... hallelujah.

"I would rather be anecdotally alive than statistically dead."
hutchibk is offline   Reply With Quote
Old 08-26-2007, 06:16 PM   #4
weezie1053
Senior Member
 
weezie1053's Avatar
 
Join Date: Nov 2006
Location: Bedford, Virginia
Posts: 134
Met with my Oncologist on Friday in conjunction with my Herceptin treatment. They checked my "bilirubin, and it was low which I was told is a good thing. Nobody can figure out why I itch other than to blame it on "stress." I have no visible rash. My mid-section itches above the bikinia line and below the breasts. The Onc told me to take Benadryl or Zurtek. It could be stress as I work full-time, and all that I work with think because I am back to work I can function at the same pace as a year ago.

Nicola, thank you for guiding me through the bloodwork testing. At least I know what it isn't.

It's a good thing I work with women so if I have a itch, I can scratch!

Louise
__________________
  • Diagnosis 06/06 - Stage II-A BC; BC was 2.5 cm, grade 2; ER/PR negative & HER-2/neu positive;
  • Mastectomy w/ reconstruction (implant) in 09/06;lymph nodes - negative;
  • AC/Cytoxin combo - 4 treatments (dose dense);
  • Taxol/Herceptin combo- 12 weekly treatments;
  • Completed chemo - 2/07; completed restruction 02/07; reduction of left breast.
  • BRCA 1 and 2 negative - 6/15/07;DX high risk for distant recurrence
  • MRI, 08/02/07 - NED
  • 1 year Anniversary - 09/07; completed Herceptin 11/07.
  • Mammo 02/14/08 - NED; MRI - 08/2008 - NED
  • 2 year Anniversary - 09/08
  • Mammo 02/09 - NED; MRI - 08/09 - NED
  • 3rd year Anniversary - 09/09
  • 5th Annivery - 09/2011 - NED
weezie1053 is offline   Reply With Quote
Reply


Posting Rules
You may not post new threads
You may not post replies
You may not post attachments
You may not edit your posts

BB code is On
Smilies are On
[IMG] code is On
HTML code is Off

Forum Jump


All times are GMT -7. The time now is 05:13 AM.


Powered by vBulletin® Version 3.8.7
Copyright ©2000 - 2024, vBulletin Solutions, Inc.
Copyright HER2 Support Group 2007 - 2021
free webpage hit counter