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Old 12-02-2010, 09:47 AM   #1
WolverineFan
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Location: Owasso, OK
Posts: 185
Is it safe to just stop taking Tamoxifin one day and start with Femara?

Hello Everyone,

I was on Femara, but after starting my period two months ago, I switched to Tamoxifin. I had a full hysterectomy on Monday, with the goal of getting me back on Femara. My question is this....can I just stop taking the Tamoxifin and begin taking the Femara or do I need to wean myself off in any way. I called my onc's office to ask this question, and spoke with her nurse, who didn't seem too sure with her answer, which didn't give me any warm fuzzies. So, I called my pharmacist and she said she wasn't sure either and that she thinks my doctor needs to chime in, but I haven't been able to get through to her. So, I thought I would ask all the wonderful people on this board because I am sure some of you know the answer to this.

Thank you so very much!
__________________
Hayley
Oklahoma

3/35/2009 - Diagnosed, age 39
5/7/09 - Mastectomy and reconstruction started. Two tumors found. Tumors were side by side. DCIS tumor was 2.8 cm, ER-, PR-, grade 2. Invasive tumor was 1.1 cm, poorly differentiated, grade 3, ER+90%, PR+95%, HER2+3. Thankfully, no node involvement.
5/29/09 - Second surgery resulting from difficulty healing from mastectomy.
6/2/09 - Began Herceptin treatments
6/23/09 - Began Taxotere and Carboplatin treatments along with Herception every 3 weeks.
10/06/09 - Completed Taxotere and Carboplatin - Yeah!!!
10/27/2009 - Herceptin maintenance and began Femara
12/10/2009 - 2nd stage reconstruction surgery
2/2010 - Body rejected saline implant
3/18/2010 - Second stage reconstruction using silicone implant
5/4/10 - Completed Herceptin - YEE-HAA!
May '10 - Body rejects silicone implant...taking a break.
11/29/10 - Hysterectomy
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Old 12-02-2010, 11:16 AM   #2
Becky
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Re: Is it safe to just stop taking Tamoxifin one day and start with Femara?

This also happened to me (but I only had an oophorectomy - but the uterus doesn't contribute to estrogen production). I could stop Tamoxifen and start right on Arimidex. That's what I did.
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Kind regards

Becky

Found lump via BSE
Diagnosed 8/04 at age 45
1.9cm tumor, ER+PR-, Her2 3+(rt side)
2 micromets to sentinel node
Stage 2A
left 3mm DCIS - low grade ER+PR+Her2 neg
lumpectomies 9/7/04
4DD AC followed by 4 DD taxol
Used Leukine instead of Neulasta
35 rads on right side only
4/05 started Tamoxifen
Started Herceptin 4 months after last Taxol due to
trial results and 2005 ASCO meeting & recommendations
Oophorectomy 8/05
Started Arimidex 9/05
Finished Herceptin (16 months) 9/06
Arimidex Only
Prolia every 6 months for osteopenia

NED 18 years!

Said Christopher Robin to Pooh: "You must remember this: You're braver than you believe and stronger than you seem and smarter than you think"
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Old 12-02-2010, 12:16 PM   #3
WolverineFan
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Re: Is it safe to just stop taking Tamoxifin one day and start with Femara?

Thanks so much, Becky. I thought it would be okay to do so, but just wanted to check. Hope all is well with you!
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Hayley
Oklahoma

3/35/2009 - Diagnosed, age 39
5/7/09 - Mastectomy and reconstruction started. Two tumors found. Tumors were side by side. DCIS tumor was 2.8 cm, ER-, PR-, grade 2. Invasive tumor was 1.1 cm, poorly differentiated, grade 3, ER+90%, PR+95%, HER2+3. Thankfully, no node involvement.
5/29/09 - Second surgery resulting from difficulty healing from mastectomy.
6/2/09 - Began Herceptin treatments
6/23/09 - Began Taxotere and Carboplatin treatments along with Herception every 3 weeks.
10/06/09 - Completed Taxotere and Carboplatin - Yeah!!!
10/27/2009 - Herceptin maintenance and began Femara
12/10/2009 - 2nd stage reconstruction surgery
2/2010 - Body rejected saline implant
3/18/2010 - Second stage reconstruction using silicone implant
5/4/10 - Completed Herceptin - YEE-HAA!
May '10 - Body rejects silicone implant...taking a break.
11/29/10 - Hysterectomy
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Old 12-02-2010, 12:52 PM   #4
caya
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Re: Is it safe to just stop taking Tamoxifin one day and start with Femara?

I think my onc. wanted me to wait one week between stopping Tamox. and starting Femara. Can't really remember exactly .. chemo brain strikes again!!

all the best
caya
__________________
ER90%+/PR 50%+/HER 2+
1.7 cm and 1.0 cm.
Stage 1, grade 2, Node Negative (16 nodes tested)
MRM Dec.18/06
3 x FEC, 3 x Taxotere
Herceptin - every 3 weeks for a year, finished May 8/08

Tamoxifen - 2 1/2 years
Femara - Jan. 1, 2010 - July 18, 2012
BRCA1/BRCA2 Negative
Dignosed 10/16/06, age 48 , premenopausal
Mild lymphedema diagnosed June 2009 - breast surgeon and lymph. therapist think it's completely reversible - hope so.
Reclast infusion January 2012
Oopherectomy October 2013
15 Years NED!!
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Old 12-02-2010, 05:52 PM   #5
Laurel
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Location: Hershey, PA. Live The Sweet Life!
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Re: Is it safe to just stop taking Tamoxifin one day and start with Femara?

I went from Tamoxifen right to Femara (if memory serves). I have no idea if it was a good move or not.....too late to fret about it now. Please let us know what your onc. says. Thanks!
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Smile On!
Laurel


Dx'd w/multifocal DCIS/IDS 3/08
7mm invasive component
Partial mast. 5/08
Stage 1b, ER 80%, PR 90%, HER-2 6.9 on FISH
0/5 nodes
4 AC, 4 TH finished 9/08
Herceptin every 3 weeks. Finished 7/09
Tamoxifen 10/08. Switched to Femara 8/09
Bilat SPM w/reconstruction 10/08
Clinical Trial w/Clondronate 12/08
Stopped Clondronate--too hard on my gizzard!
Switched back to Tamoxifen due to tendon pain from Femara

15 Years NED
I think I just might hang around awhile....

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