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Old 05-02-2014, 11:02 AM   #101
R.B.
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Re: Iodine deficiency ! - falling intakes - goitregens - competition bromine and fluo

A while ago I posted this link to a paper looking at the accumulation of iodine in various tissues in pigs.

http://www.vri.cz/docs/vetmed/46-6-153.pdf

A the moment I am wading my way through the 1000 pages plus of this not inexpensive text book on iodine http://books.google.com/books?id=7v7...iodine&f=false

I am again struck that the majority position still seems to be that most of the iodine in the body is found in the thyroid, despite the claims of some that this is not the case. I have not found any papers that definitively clarify this point.

From my reading I would suggest the relative proportions of iodide in the thyroid and wider tissue depends on the iodine intake status.

The linked paper Fig 3 and 4 clearly show that the amount of iodine in wider body tissue increases dramatically as intake increases; for example from a few micorgrams to in excess of 2mg per Kg in dorsal fat. For a 90kg pig, given the amounts of iodine found in other tissues based on the figures in the graph, the amount of iodine in a 90kg pig would mount up.

The amount in the thyroid at the highest intake is about 6 milligrams total, based on their figures.

The data in the above would suggest that at least in pigs where iodine intake is on the higher side, significantly more iodine will be found in the wider body tissues than the thyroid, which is what Venturi claims in the paper on the first page. The wider role of iodine in the body, and the examination of optimal requirements of tissues in addition to those of the thyroid may well result in the redefinition of the western guidelines on the optimal uptake of iodine.

The role of iodine / iodide / iodine in all its forms in many of the body's tissues including in female reproductive tissues remains to varying degrees to be clarified, and does not get much research funding because you cannot patent iodine, and iodine is very cheap in comparative terms. . .

Last edited by R.B.; 11-08-2014 at 12:15 PM..
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Old 07-05-2014, 02:08 AM   #102
R.B.
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Re: Iodine deficiency ! - falling intakes - goitregens - competition bromine and fluo

In the UK the Government recently asked the body responsible for setting national nutritional standards called SACN to look at iodine intake. In their consequent position statement (linked below) SACN declined to look at maternal iodine intake due to a lack of 'robust' evidence. There is a huge amount of non randomized control evidence (RCTs) as to the importance of iodine in development, and RCTs to look at the neurological impact of iodine deficits in pregnancy can never happen due to ethical implications. The refusal of SACN to look at the issue begs the question who is responsible. I put the issues below in questions to a director of NICE and Health for England (HFE) (UK health regulatory agencies) and made this delegate submission at a recent forum held by an excellent organization called the Westminster Forums. http://www.westminsterforumprojects.co.uk/ (the size of allowed submissions is limited). Importantly there is growing evidence that nutrient deficiency in the first trimester may lead to irreversible sub-optimal brain formation, for example incomplete neuron migration. There is also some evidence that fundamental factors such as abstract thought, empathy, musicality and higher human function generally may be compromised, which factors help define our humanity. Motor and more basic function is less sensitive to degradation. In a resource pressured world higher human function arguably including empathy and abstract thought is of fundamental importantance to the avoidance of conflict.


SUBMISSION

Optimal neurological development including IQ is crucial to individuals, society, and nations. Cell development in common with all cellular function, indeed life itself, is nutrient dependent. Is Health for England (HFE) ultimately responsible for national dietary and consequent nutrient intake; if not who is?

SACN reports to HFE but appears to restrict considerations to specific nutrient issues where science is ‘robust’; who then is responsible for assessment of health risks relating to significant population insufficiencies, where ‘evidence’ of risk is ‘weak’ e.g. no RCTs, but the overview fairly compelling? Further who is tasked to design and implement corrective strategies for existing identified nutritional insufficiencies.

For example SACN’s ‘Position Statement’ on iodine intake during pregnancy stated “The Subgroup advised that without further evidence it would not be possible to carry out a robust review of the UK DRV ”; although it is widely accepted very low iodine causes cretinism, and significant if ‘non-robust’ evidence suggests mild to moderate iodine deficiency may, starting in the first trimester, incrementally increase risks of irreversible sub-optimal brain formation, lower IQ 5-10 points, impair abstract thought, and lower other life-chance related developmental outcomes. (Maternal thyroxin supplies early foetus needs. Hypothyroxinemia is commonly associated with low iodine.) Accumulating evidence indicates growing iodine insufficiencies in adolescent females and pregnant women . Low income arguably increases deficiency risks. Further, DHA , and vitamin D deficiencies inter alia, likely also incrementally irreversibly compromise brain structure and function; examples of insufficiency and its effects include:

• DHA – 500 mg daily after week 22 reduced low birth weight babies by 35%, and very early pre-term deliveries by 50% (par 2.32) 7
• Iodine – 85% of adolescent females in a Belfast sample (par 5.1.1) 7 and 61% of pregnant women were classed as iodine deficient (par 5.1.5.2) 7
• Vitamin D – 75-96% of pregnant women were vitamin D insufficient 12

Iodine and vitamin D insufficiencies present particular challenges; realistically population based intake normalisation is only achievable through fortification or supplementation:

• Vitamin D food sources are limited compared to sun exposure production, which in modern day life is limited. The problem is particularly acute in the dark skinned.
• Iodine is only found in significant amounts in marine and particularly estuarine foods including seaweeds. Dairy foods are the next best source, but primarily because of cattle supplementation rather than pasture content . Other food sources of iodine are limited. Use of iodised salt, and idophors as food-industry disinfectants are falling. Iodine is lost during food preparation and storage, complicating intake assessments. Significant amounts are lost during intensive exercise. Iodine is stored in fat, so likely a greater issue in the obese. Thyroid iodide uptake is inhibited by a wide range of increasingly common foods including brassicas, perchlorates, and competing halides (bromine and chlorine), which group can partially be mitigated by higher iodine intake. Other rising factors that decrease thyroid function include high fluoride, nitrates, PCBs, chlorination, lithium, smoking, and likely polyunsaturated fat imbalances and excesses.

DHA is also mainly found in marine food, but livestock DHA could be increased somewhat by appropriate intervention. Inattention to dietary needs of livestock leads to large falls in DHA content.

In summary evidence grows of UK population wide insufficiencies in fertile and pregnant females of inter alia Omega 3 DHA, vitamin D, and iodine. Realistically addressing increasing pre and post-natal neurodevelopmental national nutrient insufficiency risks of particular relevance to the disadvantaged, including crucially iodine, vitamin D, and DHA, in fertile and pregnant females, can only be achieved by food supplementation; this will require bringing together health agricultural and food sectors in a quest for optimal solutions; the question is by whom?


1. SACN position statement on iodine and health - February 2014 – par. 122 http://www.sacn.gov.uk/pdfs/sacn_pos...and_health.pdf
2. Comprehensive Handbook of Iodine: Nutritional, Biochemical, Pathological and Therapeutic Aspects - Victor R. Preedy, Gerard N. Burrow, Ronald Ross Watson - Academic Press, 17 Mar 2009 - Medical - 1334 pages – in part on line - multiple references e.g - (FYO I purchased a copy and have read it twice from cover to cover)
http://books.google.com/books?id=7v7...gnancy&f=false
3. Effect of inadequate iodine status in UK pregnant women on cognitive outcomes in their children: results from the Avon Longitudinal Study of Parents and Children (ALSPAC) - Sarah C Bath PhD, Colin D Steer MSc, Prof Jean Golding FMedSci, Pauline Emmett PhD, Prof Margaret P Rayman DPhil, - The Lancet, Volume 382, Issue 9889, Pages 331 - 337, 27 July 2013 - http://www.thelancet.com/journals/la...436-5/abstract
4. Section IV - The Scientific Basis for the Elimination of Brain Damage due to Iodine Deficiency – F Delange and B S Hetzel - http://www.iccidd.org/cm_data/hetzel-e-section4.pdf
5. Mild iodine deficiency in pregnancy in Europe and its consequences for cognitive and psychomotor development of children: A review – Caroline Trumpff, Jean De Schepper, Jean Tafforeau, Herman Van Oyen,
Johan Vanderfaeillie, Stefanie Vandevijvere – J Trace Elem Med Biol (2013) - http://www.iccidd.org/cm_data/2013_T...evelopment.pdf
6. Chapter 20 - The Iodine Deficiency Disorders - Creswell J. Eastman, M.D Michael Zimmermann, M.D – Thyroid Disease Manager - http://www.thyroidmanager.org/chapte...ncy-disorders/
7. Benefits of Docosahexaenoic Acid, Folic Acid, Vitamin D and Iodine on Foetal and Infant Brain Development and Function Following Maternal Supplementation during Pregnancy and Lactation. - Nancy L. Morse - Nutrients. Jul 2012; 4(7): 799–840 - http://www.ncbi.nlm.nih.gov/pmc/articles/PMC3407995/
8. Recommendations; UK 150mcg; WHO 250mcg; American Paediatrics 220 - 290mcg, Japan 3000mcg.
9. Dietary (n-3) Fatty Acids and Brain Development – Sheila M. Innis - J. Nutr. April 2007 vol. 137 no. 4 855-859
http://jn.nutrition.org/content/137/4/855.full
10. Omega-3 Fatty Acid Deficiency in Infants before Birth Identified Using a Randomized Trial of Maternal DHA
Supplementation in Pregnancy - Kelly A. Mulder, D. Janette King, Sheila M. Innis - LoS ONE 9(1): e83764. doi:10.1371/journal.pone.0083764 - http://www.plosone.org/article/fetch...esentation=PDF
11. DHA Deficiency and Prefrontal Cortex Neuropathology in Recurrent Affective Disorders – Robert K McNamara - J Nutr. Apr 2010; 140(4): 864–868. - http://www.ncbi.nlm.nih.gov/pmc/articles/PMC2838627/
12. Vitamin D deficiency and insufficiency in pregnant women: a longitudinal study - Valerie A. Holmes, Maria S. Barnes, H. Denis Alexander, Peter McFaul and Julie M. W. Wallace - British Journal of Nutrition / Volume 102 / Issue 06 / September 2009, pp 876-881 http://journals.cambridge.org/action...07114509297236
13. Vitamin D deficiency in pregnancy - still a public health issue. - McAree T1, Jacobs B, Manickavasagar T, Sivalokanathan S, Brennan L, Bassett P, Rainbow S, Blair M.- Matern Child Nutr. 2013 Jan;9(1):23-30. doi: 10.1111/mcn.12014.- http://www.ncbi.nlm.nih.gov/pubmed/23230904
14. Vitamin D3 and brain development - D Eyles, J Brown, A Mackay-Sim, J McGrath, F Feron http://www.direct-ms.org/pdf/VitDGen...evelopment.pdf
15. Developmental vitamin D deficiency causes abnormal brain development. - Eyles DW, Feron F, Cui X, Kesby JP, Harms LH, Ko P, McGrath JJ, Burne TH. - Psychoneuroendocrinology. 2009 Dec; 34 Suppl 1:S247-57. doi: 10.1016/j.psyneuen.2009.04.015. - http://www.ncbi.nlm.nih.gov/pubmed/19500914
16. The geochemistry of iodine and its application to environmental strategies for reducing the risks from iodine deficiency disorders http://nora.nerc.ac.uk/10724/1/CR03057N.pdf
17. To refine and confirm the level of selenium and iodine supplementation for breeding ewes http://www.eblex.org.uk/wp/wp-conten...ort-190214.pdf
18. POLICY STATEMENT Iodine Deficiency, Pollutant Chemicals, and the Thyroid: New Information on an Old Problem – COUNCIL ON ENVIRONMENTAL HEALTH – American Academy of Pediatrics - DOI: 10.1542/peds.2014-0900 ; originally published online May 26, 2014; Pediatrics http://pediatrics.aappublications.or....full.pdf+html
19. http://her2support.org/vbulletin/showthread.php?t=53928 I am R.B.
20. Modern organic and broiler chickens sold for human consumption provide more energy from fat than protein. Wang Y, Lehane C, Ghebremeskel K, Crawford MA. - Public Health Nutr. 2010 Mar;13(3):400-8. doi: 10.1017/S1368980009991157. - http://www.ncbi.nlm.nih.gov/pubmed/19728900

Last edited by R.B.; 07-05-2014 at 08:50 AM..
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Old 07-07-2014, 03:52 AM   #103
dauntricastewart
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Re: Iodine deficiency ! - falling intakes - goitregens - competition bromine and fluo

The Deficiency of Iodine in Asia is not so much prominent, but in the West the percentage of Deficiency of Iodine is higher which is major factor causing diseases related Breast.
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Old 07-13-2014, 03:17 AM   #104
R.B.
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Re: Iodine deficiency ! - falling intakes - goitregens - competition bromine and fluo

More sources of flouride from Flouride Alert - I have copied and pasted some of the content below, but it is worth visiting the site - there is more mind numbing information on this page in relation to developmental issues - flouride can both be used to kill bugs on foods and fumigate warehouses to kill bugs in them - apparently in the US it is not obligatory to move food when fumigating warehouses which where relevant could result in very high fluoride loads in food twice a year! - so you really do not know what little extras you might be getting this Thanksgiving or Christmas

http://fluoridealert.org/issues/sources/f-pesticides/

Pesticides

Due to its high toxicity, fluoride has long been used as a pesticide. In the United States, there are currently two fluoride-based pesticides that are allowed to be sprayed on food. These are: cryolite and sulfuryl fluoride.

2) According to data from the USDA (2005), the average fluoride levels in grape products are as follows:

White grape juice = 2.13 ppm
White wine = 2.02 ppm
Red wine = 1.05 ppm
Raisins = 2.34 ppm

3) Many juice drinks that are not labeled as “grape juice” use grape juice as a filler ingredient. The use of cryolite thus contaminates many juices with fluoride.

4) Cryolite is also allowed to be added to the following products (although it is unclear how many producers actually do so, and what the resulting fluoride levels are):

Apricot, Broccoli, Brussels Sprout, Cabbage, Cauliflower, Citrus fruit, Collards, Eggplant, Kale, Kiwifruit, Kohlrabi, Lettuce, Melon, Nectarine, Peach, Pepper, Plum, Pumpkin, Squash (summer & winter), Tomato, and a number of Berries (Blackberry, Blueberry (huckleberry) Boysenberry, Cranberry, Dewberry, Loganberry, Raspberry, Strawberry, Youngberry).



Direct Fumigation of Food

6) The EPA also allows food processors to use sulfuryl fluoride as a direct fumigant of certain foods. This means that food processors can purposely spray sulfuryl fluoride directly onto certain foods.

7) Unlike structural fumigation (which takes place once or twice a year), direct fumigation is a routinely performed procedure. Thus, foods that can be directly fumigated with sulfuryl fluoride will consistently have elevated fluoride levels.

8) According to EPA’s estimates, some of the foods that will be most commonly fumigated are cocoa powder, dried beans, walnuts and dried fruits.

9) EPA estimates that, if the current regulations are not rescinded, 100% of cocoa powder, 100% of dried beans, 99% of walnuts, 69% of dried fruits, 10% of walnuts, 10% of tree nuts, and 3% of rice will be fumigated.

10) When fumigated the average fluoride levels in fumigated food is:

Brown rice = 12.5 ppm
Cocoa powder = 8.4 ppm
Almonds = 5.3 ppm
Tree nuts = 5.3 ppm
Dried beans = 4.5 ppm
White rice = 4.5 ppm
Walnuts = 2.4 ppm
Dried fruits = 1 ppm

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Old 07-13-2014, 03:31 AM   #105
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Re: Iodine deficiency ! - falling intakes - goitregens - competition bromine and fluo

And something I had not checked before - does fluoride cross the placenta - yes - http://www.ncbi.nlm.nih.gov/pubmed/2182701 - which has scary potential implications.

The implications would be greater in those who are at risk of iodine deficiency and insufficiency in pregnancy.

Might it affect fetal brain development either directly or by inhibition of thyroid function and so iodine metabolism - Fluoride Alert saved me the trouble of looking for data - based on fetal autopsies high fluoride intake is associated with serious developmental abnormalities .

Some abstracts from the link below which is well worth a visit - truly an I want to scream moment - if mitochondria do not work everything is affected.

This data was of course related to high flouride intake, but as already discussed the uptake of flouride is altered by many factors including the form in which it is ingested, wider mineral uptake and availability, so the questions as to whether those who have intakes from water, food, drugs, excessive toothpaste, low mineral and iodine intake and other risks that may be additive are at higher risk of non optimal fetal development is as yet unanswered.




http://fluoridealert.org/studies/brain05/



The human placenta does not prevent the passage of fluoride from a pregnant mother’s bloodstream to the fetus. As a result, a fetus can be harmed by fluoride ingested pregnancy. Based on research from China, the fetal brain is one of the organs susceptible to fluoride poisoning.

As highlighted by the excerpts below, three Chinese studies have investigated fluoride’s effect on the fetal brain and each has found evidence of significant neurological damage, including neuronal degeneration and reduced levels of neurotransmitters such as norepinephrine. As noted by Yu (1996), “when norepinephrine levels drop the ability to maintain an appropriate state of activation in the central nervous system is weakened.” Studies of fluoride-treated animals have reported similar effects, including lower levels of norepinephrine. (Kaur 2009; Li 1994).

The following study involves the same fetal tissue that was examined in the Yu (1996) and Dong (1993) studies. Rather than investigating fluoride’s effect on the brain, however, this study examined fluoride’s effect on the ultrastructure of cells in several tissues in the body, including from the thyroid gland. As can be seen in the following description, the fetuses from the fluoride-exposed women were experiencing a systemic toxic effect.

Conclusions: Fluoride damage to cell structures was multifaceted. Cell membranes, mitochondria, rough endoplasmic reticulum, and nuclear membranes could all be damaged at the time of fluorosis.”


another study said

These changes indicate that fluoride can retard the growth and division of cells in the cerebral cortex. Fewer mitochondria, microtubules, and vesicles within the synapses could lead to fewer connections between neurons and abnormal synaptic function, influencing the intellectual development after birth. These questions await further research.
SOURCE: Han H, et al. (1989). Effects of fluorine on the human fetus. Chinese Journal of Control of Endemic Diseases 4:136-138. [See study]

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Old 07-13-2014, 04:36 AM   #106
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Re: Iodine deficiency ! - falling intakes - goitregens - competition bromine and fluo

Does the placenta reduce the passage of fluoride to the baby? It might this paper asked that question and observed lower fluoride concentrations of the fetus side of the placenta to the maternal side.

Could western diet alter placental function, permeability etc; I would be surprised if it did not.

So as ever things are rarely simple.


http://njirm.pbworks.com/f/3Role+of+...t+flurosis.pdf
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Old 07-26-2014, 01:15 PM   #107
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Re: Iodine deficiency ! - falling intakes - goitregens - competition bromine and fluo

Nitrates in water and thyroid function. There are several papers suggesting that nitrate pollution of well water may affect thyroid function. This is the biggest effect I have seen. I do not have access to the full paper but the potential implications are depressing.

http://www.ncbi.nlm.nih.gov/pubmed/17447577

Arch Environ Occup Health. 2005 Nov-Dec;60(6):317-9.
Iodine status of children living in areas with high nitrate levels in water.
Gatseva PD1, Argirova MD.
Author information
Abstract

Several researchers have suggested a possible relationship between nitrate intake and the development of goiter in children. The present cross-sectional study included schoolchildren between the ages of 11 and 14 years from 2 villages in Bulgaria with high and low nitrate levels in drinking water. The comparison between the median urinary iodine levels of the total number of exposed (179.0 microg/l) and nonexposed (202.50 microg/l) children showed statistically significant differences. The relative risk for the children exposed to high nitrate levels in drinking water, expressed as the odds ratio, was 8.145 (95% confidence interval = 1.67-39.67). The authors considered this to be very significant. They found a statistically significant difference for the prevalence of goiter among the exposed and nonexposed children. The results of the study confirmed the role of high nitrate levels in drinking water as a health risk factor for thyroid dysfunction.

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Old 08-24-2014, 02:57 AM   #108
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Re: Iodine deficiency ! - falling intakes - goitregens - competition bromine and fluo

Sea vegetables are great for this. (If someone already mentioned this, I'm sorry. I looked back and didn't see it mentioned). There are so many varieties available that have different flavors - but if you want to start with something on the milder side, try arame. You can sprinkle it on salads, for starters. Also, you can make snack chips out of nori.
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Old 10-03-2014, 06:04 AM   #109
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Re: Iodine deficiency ! - falling intakes - goitregens - competition bromine and fluo

If anybody is in the UK and interested I am speaking at a Royal Society of Medicine food section conference on hidden nutritional deficiencies in my new role as recently appointed Chair of the McCarrison Society, which is a venerable society with its own widely recognized Journal 'Nutrition and Health'.

The Society has a long illustrious history, but is in need of a bit of revamping including a new web site.

I will be looking in whistle-stop fashion at deficiencies in nutrients particularly Iodine, Vitamin D, minerals, and imbalances in Omega 3 and 6 set within the context of the shoreline diet which arguably provided the conditions for out existence.

I am hoping to make the McCarrison Society a forum to bring together the Food Agricultural and Health sectors to the same table, which they never are, to try and bring focus on deficiencies such as Vitamin D, Iodine and secure the implementation of strategies to address them.

This is the link to the conference.


http://www.rsm.ac.uk/events/fhf01

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Old 10-03-2014, 10:40 AM   #110
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Thumbs up Re: Iodine deficiency ! - falling intakes - goitregens - competition bromine and fluo

RB,

Thank you for all the time and effort you make to keep us up to date on the information available, and for your expertise in coordinating the possibility for interaction and discussion at such a level as this conference.

I do hope someone from this site will attend. Thanks for providing early notice here to make that possible.

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Old 10-20-2014, 11:32 AM   #111
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Re: Iodine deficiency ! - falling intakes - goitregens - competition bromine and fluo

GREAT to see the forum back Very many thanks to all those involved in putting this invaluable resource back on the road.

FREE STUDENT PLACES (UK accredited conference at the Royal Society of Medicine - food section)

There are a small number of free student (medical nutrition related) places at the above, but the offer closes tomorrow apparently. If interested please Pmail me

Availability depends on demand but I will be delighted to pass the application on.

The spaces have now gone - sorry about the previous typos - did not see them at the time

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Old 01-01-2016, 02:42 PM   #112
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Re: Iodine deficiency ! - falling intakes - goitregens - competition bromine and fluo

How time flies!

Just found this looking for something else.

This is an excellent paper on iodine selenium and breast cancer, which emphasizes the interconnected nature of selenium and iodine and need for adequate amounts of both.

It also considers the relevance of fibrocystic breast disease, and the relevance of iodine thereto.

It also links in thyroid function.

It also recognizes that iodine is transported by other mechanisms than thyroxine including attachment to fats.

It was written in 2000 and emphasizes the need for more research which is still required in 2016.

It is available in full for free as a PDF.


Hypothesis: Iodine, selenium and the development of breast cancer

http://www.iodineresearch.com/files/...ast_cancer.pdf

An abstract

"High-grade fibrocystic disease (i.e., ductal or lobular
hyperplasia, but especially atypical hyperplasia) is gen-
erally believed to be a precursor to ductal carcinoma
in situ (DCIS) and subsequent invasive/metastatic car-
cinoma. Other symptoms of benign breast disease,
including cyclical mastalgia [12] and apocrine cysts
[13], have also been associated with an increased breast
cancer risk. In the USA it has been estimated that 50±
90% of women experience Fibrocystic disease during
their lifetime [14, 15]; a rate so high that some have
suggested that this condition should no longer be
classiĆed as a disease [14, 15]. However, downgrading
the disease status simply due to prevalence estimations is
questionable when this condition, in populations at low
risk for breast cancer, is so much less common [16].
Gravelle et al. [17] found that healthy British women
had signiĆcantly less low-risk (low-density) and a
greater proportion of high-risk (high-density) breast
parenchymal patterns than Japanese women. Further-
more, immigration studies suggest that these breast
parenchymal patterns may be inŘuenced by nongenetic
factors. For example, Sasamo et al . [18] found that the
prevalence of breast epithelial hyperplasia was similar
between Japanese women (18.4%) and Japanese issei
Hawaiians (immigrant generation) (14.5%), but signif-
icantly lower than nisei Hawaiians (second generation)
(51.4%)."
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Old 07-04-2016, 10:00 AM   #113
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Re: Iodine deficiency ! - falling intakes - goitregens - competition bromine and fluo

An old but thought provoking paper suggesting possibly that thyroid dysbiosis is a risk in breast cancer. The author makes the point that the number are small etc, but it is nonetheless thought provoking including the observation that apparently breast cancer was rare in those that were hyperthyroid.

Hypothyroidism is linked with a greater risk of breast cancer.

http://www.ncbi.nlm.nih.gov/pmc/arti...03628-0022.pdf
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Old 03-01-2017, 06:35 AM   #114
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Re: Iodine deficiency ! - falling intakes - goitregens - competition bromine and fluo

well, does anybody know that iodine allergy exists? I didn't..till I found I have it.
The iodine does not induce an allergic reaction, but getting inside the body or on the skin, a microelement enters into a special reaction, which produces a foreign protein to the organism, and the existence of this element causes the development of allergic symptoms.
http://stopallergyguide.com/iodine-allergy/ and now I don't know how to compensate for the iodine deficiency.
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Old 03-06-2017, 03:55 AM   #115
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Re: Iodine deficiency ! - falling intakes - goitregens - competition bromine and fluo

This link http://www.dermnetnz.org/topics/iodine/
states,


"Iodine allergy

The term ‘iodine allergy’ is commonly used, but is actually a misnomer. Iodine is a trace element present throughout the body, and is essential for the production of thyroid hormones. It is not possible to have a true allergy to elemental iodine.

‘Iodine allergy’ usually refers to an allergic-type reaction to iodinated radiological contrast media or, less commonly, an allergic contact reaction to povidone-iodine (Betadine™) antiseptics."


which would make more sense to me than the link in the post above namely http://stopallergyguide.com/iodine-allergy/ It looks as if people are conflating reaction to medications, sea food etc, with the elemental iodine/iodide; they are not the same thing.



If anybody comes across a reaction to iodine so Lugols or similar can they please post the information.

Of course it is important to seek medical advice when looking at iodine intakes and always be sensible and mindful in all aspect of diet and supplementation.

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Old 06-21-2017, 10:08 AM   #116
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Re: Iodine deficiency ! - falling intakes - goitregens - competition bromine and fluo

An informative review on iodine and cancer.

"There is substantial evidence that iodine deficiency is a modifiable risk factor in cancers of the stomach and breast."

- See more at: http://www.naturalmedicinejournal.co....nSs0Wc0v.dpuf

"Abstract

Iodine is an essential element in human physiology. Its role in thyroid function is well known and heavily weighted in the literature. Its putative role as an anticarcinogenic agent is just beginning to be widely appreciated. The molecular effects of iodine as well as ongoing epidemiological evidence points to its probable role in prevention of cancers through its antioxidant, antiinflammatory, prodifferentiating, and proapoptotic effects. This is particularly evident with stomach and breast cancers but may be relevant for many other cancers that have yet to be substantially studied."

"Epidemiological evidence also suggests that thyroid disorders, particularly goiter, may be associated with breast cancer incidence and/or mortality.5–8 Other cancers associated with goitrogenic state include prostate cancer, endometrial, ovarian, colorectal, and thyroid cancer. It is not clear whether these associations are due to an underlying hypothyroid state, the presence of occult autoimmune processes, or iodine deficiency itself."
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Old 08-30-2017, 02:39 PM   #117
R.B.
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Re: Iodine deficiency ! - falling intakes - goitregens - competition bromine and fluo

Found whilst looking for something else - in this instance iodine in Japanese breast milk - as is often the case.

As often the case with issues where there is no significant financial incentive because you cannot patent something, on this occasion iodine, and it is cheap, more research is required.

The paper is not too 'technical'. I abstract bits below to give a flavor of the review.

Free Full paper
http://jeffreydachmd.com/wp-content/...ntrol-2000.pdf

"In this paper we have focused on deficient iodine and
selenium intake as risk factors for breast cancer;
however, these elements have also been implicated in
the development of other hormone-dependent diseases,
such as ovarian [5, 97], uterine [5, 97, 98] and prostatic
carcinoma [99, 100]. In view of the complementary
nature of these two nutrients, a re-evaluation of optimal
iodine and selenium intake may be required. In-depth
studies, examining a combined role for these elements in
the prevention and treatment of cancer and other
degenerative diseases, would be a step in the right
direction"

"In estradiol-treated rats, iodine deficency has been
shown to lead to pathological changes similar to those
seen in benign breast disease ± cystic changes, per-
iductal fibrosis and lobular hyperplasia [19, 20].
Conversely, dietary iodine reintroduction has been
shown to reverse these pathological changes [20].
Thus, iodine deficiency appears to enhance mammary-
tissue sensitivity to estrogen.
"

"As with prevention, a role for iodine in the treatment
of breast cancer awaits further study. Traditional
eastern Asian medicine has long used iodine-rich sea-
weeds as a cancer treatment to ``soften'' tumors and
``reduce'' nodulation
[30, 31]. Recent work with animal
systems seems to support an antitumor e€ect for iodine"

Last edited by R.B.; 08-30-2017 at 02:43 PM..
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Old 09-07-2017, 04:12 AM   #118
R.B.
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Re: Iodine deficiency ! - falling intakes - goitregens - competition bromine and fluo

A perspective from medically qualified 'nutritonalist' (more qualifications than I have) that is put in plain terms. I have not checked his CV, and would take a more nuanced perspective on the RDA. Also the ideal dose he proposes is open to question, but Japanese intakes are higher than those in the west. As above the fluoride debate is heated and complex. Excess oxidative stress is a magor issue and certainly it happens in different time scales that reflect cellular function and 'purpose', but from a quick skim I have reservations about the direction of what is proposed, and my comments and posting of this post, is very much restricted to the iodine page, as I do not have the time to read all the site, comment on it etc.

Sadly space for debate is needed as much about iodine remains to be researched and quantified.

The web page is none the less a succinct and useful summary of issues to consider and research, ideally at the same time as talking to your doctor.



IODINE, A CRITICAL NUTRIENT

http://www.drlwilson.com/ARTICLES/IODINE.htm

by Dr. Lawrence Wilson

"One of the most important and overlooked minerals today is iodine. Iodine is needed in the thyroid gland to produce thyroid hormones. However, iodine is also required for every tissue of the body!

It is called the endocrine mineral because it is important not only for the thyroid gland, but also for the adrenal glands, ovaries, breasts, prostate gland, and the entire hormone system of the body. "

Last edited by R.B.; 09-07-2017 at 04:28 AM..
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Old 10-10-2017, 08:14 AM   #119
Romancelfot
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Re: Iodine deficiency ! - falling intakes - goitregens - competition bromine and fluo

Is Iodine closely related with hyperthyriodism?
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