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Old 09-14-2015, 08:12 AM   #1
europa
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Yellowing of the eyes

Hi friends,

A dear friend of mine has stage 4 and they have been giving her the something called the smart bomb. It came out last year. She is very private so asking her what exactly is in the smart bomb.
But yesterday when I saw her, her eyes were noticeably yellow. So two questions

1. Can anything other than an issue with her liver, like mets to liver, cause jaundice.
2. If it's in her liver, she is Her2+, what treatment combos could be a good option.

thank you friends.

P
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DX 10/2011
PET Scan + MRI 10/2011
Lumpectomy 11/11/11
Stage 2B +++ ER+(10%), PR+(5%), HER2+++(1 positive node, 1 micromets to second node)
AC started 12/2011 ended 1/2012
Taxol + Herceptin weekly for 12 weeks ended 4/2012
30 zaps of radiation done 6/2012
Tamoxifen 6/2012
every 3 weeks of Herceptin for another year.
Metformin Trial 8/12
10/12 MRI- CLEAR
01/13 BRAIN MRI- CLEAR!
01/13 Neck MRI- CLEAR!
FINISHED HERCEPTIN 1/9/2013...Woot Woot
Starting Walter Reed Vaccine Trial 2/13
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02/2015 through 11/2015 emergency D&Cs for Tamoxifen induced uterine polyps which caused uncontrollable hemorrhaging
12/2015 blood clot to left leg caused by Tamoxifen. No longer taking it. On Xarelto, a blood thinner
12/2015 Ablation to prevent hemorrhaging from potential issues with Tamoxifen residue in my system
1/2016 continuing journey without hormonal therapy. Reevaluating the option of a hysterectomy and oopherectomy.
4/1/2018 2mm stroke. Yes, stroke! No cause ever found but they believe it was a migraine that went bonkers and created a tiny clot. No deficits. I was back to normal with 24hrs. Now on baby aspirin for life.
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01/07/2019 Mastectomy and expanders put in
3/22/2019 Vtach, almost died. Cause unknown.
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7/21/2020 Off of all drugs but a baby aspirin because of the stroke in 2018.


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Old 09-14-2015, 10:53 AM   #2
Becky
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Re: Yellowing of the eyes

For her2, a smart no.b is tdm-1 (Kalyda) It can cause liver problems and isn't necessarily a sign that there are mets in the liver of she didn't already have them.
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Kind regards

Becky

Found lump via BSE
Diagnosed 8/04 at age 45
1.9cm tumor, ER+PR-, Her2 3+(rt side)
2 micromets to sentinel node
Stage 2A
left 3mm DCIS - low grade ER+PR+Her2 neg
lumpectomies 9/7/04
4DD AC followed by 4 DD taxol
Used Leukine instead of Neulasta
35 rads on right side only
4/05 started Tamoxifen
Started Herceptin 4 months after last Taxol due to
trial results and 2005 ASCO meeting & recommendations
Oophorectomy 8/05
Started Arimidex 9/05
Finished Herceptin (16 months) 9/06
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NED 18 years!

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