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Old 06-22-2008, 04:36 AM   #1
R.B.
Senior Member
 
Join Date: Mar 2006
Posts: 1,843
The Role of Omega 3 and 6 in breast cancer

Please see the Greek Diet Thread.

I have set a new title in case Omega 3 and 6 might catch the interest and the Greek Diet did not for new visitors to the site who are not aware the Greek Diet thread is primarily about omegas 3 and 6 in diet.

http://her2support.org/vbulletin/showthread.php?t=24410

Blood. 2008 Apr 1;111(7):3514-21. Epub 2008 Jan 23.Click here to read Links
Modulation of angiogenesis by omega-3 polyunsaturated fatty acids is mediated by cyclooxygenases.
Szymczak M, Murray M, Petrovic N.

Pharmacogenomics and Drug Development Group, Faculty of Pharmacy, University of Sydney, Camperdown, Australia.

"Both epidemiologic and experimental findings suggest that omega-3 polyunsaturated fatty acids (omega-3 PUFAs), which are almost absent from typical Western diets, exert protective effects against cancer progression, although the precise mechanism of this suppression remains unknown. One of the potential targets for omega-3 PUFAs in cancer suppression is angiogenesis, a process of new blood vessel formation within rapidly growing tumors. Here, we demonstrate that omega-6 PUFAs stimulate and omega-3 PUFAs inhibit major proangiogenic processes in human endothelial cells, including the induction of angiopoietin-2 (Ang2) and matrix metalloprotease-9, endothelial invasion, and tube formation, that are usually activated by the major omega-6 PUFA arachidonic acid"
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