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Old 03-03-2018, 08:30 PM   #1
Pamelamary
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Join Date: Apr 2012
Location: Melbourne, Australia
Posts: 494
Whoops!

So recently celebratory, but I have just found out that I have fractured a bone in my foot. Too many years of Denosumab and Zometa? So now I am the lucky owner of a stylish black moon boot and am hobbling around as best as I can. Takes away the independence somewhat. Due to travel to Sri Lanka in 6 weeks, but it is unlikely I will be healed by then - maybe catching a lot of tuk-tuks.
Regards.... Pam.
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Diagnosed 2004: Lumpectomy - 2 tumours, both grade 1 infiltrating duct carcinoma, about 12mm. ER+,
C-erbB-2 status 3+.
Clear margins, no nodal involvement.
Radiotherapy, i year Tamoxifen, 4 years Arimidex.
Rediagnosed 2012: Multiple bone metastases.
3/12: began on Marianne trial - T-DM1 + Pertuzamab/Placebo.
5/12:Unexpected development of numerous bilateral liver mets. Came off trial.
Started Docetaxol/ Herceptin + Zometa.
8/12:Bones stable +major regression in liver (!)
9/12:Can't take any more Docetaxol! Start on Herceptin and Tamoxifen. Cross fingers!
Changed to Denosumab.
11/12: Scan shows stable - yay!
11/13: Still stable :-) !!!
1/16: All stable, but lowered calcium, so switched to Zometa 3 monthly.
2/19: Happily still stable on Herceptin, Letrozole and 3 monthly Zometa.
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