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Old 02-28-2008, 08:58 PM   #1
Kim in DC
Senior Member
 
Join Date: Nov 2004
Posts: 190
Started Omnitarg(placebo)Taxotere, Herceptin trial

Yesterday was my official start in the trial they are calling "Cleopatra". It is a phase III trial, recruiting 800 patients. It must be your first treatment for metastatic breast cancer.

I either received Taxotere, Herceptin and Omnitarg or Taxotere, Herceptin and a Placebo. Treatments are every 3 weeks. They evaluate you after 3 cycles. If I am receiving Omnitarg, I will be receiving 2 out of the 3 drugs of what I like to call the "triple threat" combo that Dr. Osborn was talking about.

I will see what the scans say and then decided if I want to try to get into the DM1 trial. I told my onc about how well you girls were doing and she is very excited. She will be eligible to participate in May or June.

Kim
__________________
8/98 dx right breast
5/2003 tram flap right breast
8/2004 dx new primary left breast with inflammatory bc
er/pr-, her2neu+++
8/19 taxotere and herceptin
1/15/2005 Navelbine/Herceptin
4/2005 radiation and Herceptin
5/15/2005 Herceptin alone
2/12/2008 skin biopsy positive
2/14/2008 met to sternum, possibly right breast
2/27/08 Start omitarg, herceptin, taxotere trial
3/17/08 Kicked off trial because I started too close to my last herceptin
3/19 start tykerb xeloda
Right breast confirmed met
5/15/08 skin mets gone, no hypermetabolic activity in breast, sternum healing
8/24/08 scans still look good. sternum still active with scarring. No evidence of progression
10/08 Progression in sternum
12/08 Start TDM1 trial
1/09 Scans show stable
12/09 1 year on TDM1 still stable
10/10 progression in chest and liver
11/10 false positive of liver mets; tykerb and herceptin
4/11 Tykerb/Herceptin/Xgeva
4/11 Rads to Sternum
5/12/12 NED Herceptin/Zometa
3/16/19 still NED Herceptin/Zometa very 6months
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Old 03-01-2008, 09:47 PM   #2
kareneg
Senior Member
 
Join Date: Nov 2005
Location: Lincoln, Rhode Island
Posts: 371
Smile

Dear Kim,

This sounds so exciting I pray everything goes well. Please keep us posted on your trial. Will you know if they give you the Omnitarg? Again let us know how you make out and thanks for being apart of this trial it give everyone hope.
__________________
Love and Hope
Karen

IDC
DX 1998 STAGE I ER+/ PR+
AC CHEMO TILL FEB 1999
Tamxofin till 2001
2001 exstensive liver mets and mets to lungs
Started weekly taxol
Jan 2002 found out I was strongly HER2POS+++ started herceptin continued with taxol and herceptin till June 2002 then from June 2002 till Jan 2005 just herceptin and Arimidex
2005 Navelbine herceptin had RFA Then back on taxol with herceptin
April 2006 progression again went on clinical trial with tykrerb/herceptin progressed on the started Xeloda/ herceptin
Feb 2007 started Doxil
August 2007 Taxotere,Carboplatin and Herceptin exstensive mets to liver and pancreas
October 2007 Had to stop Carboplatin due to sever allergic reaction
Jan 2008
Stopped Taxotere due to progression now on Gemzar and Herceptin
March 2008 Starting Carboplatin, Abraxane, and Herceptin.
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